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Medical Sciences Forum, Volume 12, Issue 1

ECA 2022 2022 - 44 articles

The 2nd International Electronic Conference on Antibiotics—Drugs for Superbugs: Antibiotic Discovery, Modes of Action and Mechanisms of Resistance

Online | 15–30 June 2022

Volume Editors:
Manuel Simões, University of Porto, Portugal
Marc Maresca, Aix-Marseille University, France

Cover Story: This volume presents a collection of contributions that were made to the virtual event, “The 2nd International Electronic Conference on Antibiotics—Drugs for Superbugs: Antibiotic Discovery, Modes of Action and Mechanisms of Resistance”, on 15–30 June 2022. Today, we know that bacteria will resist and persist against all kinds of antibiotics. This is easy to understand if we consider that bacteria, during the course of their evolution, have faced situations even more difficult than antibiotic exposure. Additionally, this becomes worse when bacteria act as a community, i.e., as a biofilm. The aim of this conference (ECA 2022) was to provide an opportunity to representatives of academia, industry, and health services to discuss and advance our current knowledge on how to control microorganisms.
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Articles (44)

  • Abstract
  • Open Access
911 Views
2 Pages

In Vitro Activity of Cefiderocol and Comparators against Multi-Drug Resistant Acinetobacter baumannii Isolates

  • Areti Tychala,
  • Efthymia Protonotariou,
  • Paraskevi Mantzana,
  • Georgios Meletis,
  • Ioanna Gkeka and
  • Lemonia Skoura

Acinetobacter baumannii is an aerobic Gram-negative bacterium which causes facultative hospital infections and, in settings such as Greece, exhibits high resistance rates against most antimicrobial agents [...]

  • Proceeding Paper
  • Open Access
1,479 Views
7 Pages

Antibiotic Prescriptions in Pediatric Patients Hospitalized with Pneumonia at a University Hospital

  • Rafael Rodrigues Leite,
  • Felipe Lemos Esteves do Amaral,
  • Sara Maria Gomes Bié,
  • Maria Fernanda Bandeira da Silva,
  • Sandriny Maria de Almeida Oliveira,
  • José Dilbery Oliveira da Silva and
  • Sávio Benvindo Ferreira

Community-acquired pneumonia (CAP) is the leading cause of hospitalization in the Brazilian Unified Health System, with a mortality rate of 18% in children under 5 years of age. Therefore, there is a need for an effective treatment, including antibio...

  • Abstract
  • Open Access
1,267 Views
2 Pages

Serratia marcescens is a bacterial species associated with different types of infections, including hospital-acquired infections [...]

  • Proceeding Paper
  • Open Access
2,069 Views
8 Pages

In Silico Analysis and PCR Characterization of non-Tn4401 Transposable Elements in Pseudomonas aeruginosa

  • Julián Ruiz-Castellanos,
  • Ricaurte Alejandro Márquez-Ortiz,
  • Deisy Abril,
  • Daniela Forero Hurtado,
  • Ginna Tíjaro,
  • Zayda Corredor-Rozo,
  • Javier Escobar-Pérez and
  • Natasha Vanegas

The multi-resistance presented by P. aeruginosa has greatly increased due to the presence of genes for carbapenemases such as blaKPC. The dissemination of this gene has been associated with the Tn4401, the main mobile genetic element that carries bla...

  • Abstract
  • Open Access
1,116 Views
1 Page

Solid-Phase Microextraction as an Antibiotic Resistance Detector in Staphylococcus aureus Strains

  • Justyna Paleczny,
  • Malwina Brożyna,
  • Marzenna Bartoszewicz and
  • Adam Feliks Junka

Bloodstream infections, which result from introducing contaminated implants or prostheses to a patient’s body, are commonly caused by Staphylococcus aureus strains. The occurrence of staphylococcal-related bloodstream infection correlates with...

  • Abstract
  • Open Access
1,258 Views
2 Pages

Is There a Relationship between Biofilm Forming-Capacity and Antibiotic Resistance in Staphylococcus spp.? In Vitro Results

  • Matthew Gavino Donadu,
  • Marco Ferrari,
  • Vittorio Mazzarello,
  • Stefania Zanetti,
  • Ivan Kushkevych,
  • Simon K.-M. R. Rittmann,
  • Anette Stájer,
  • Boglárka Ónodi,
  • Zoltán Baráth and
  • Edit Urbán
  • + 1 author

Staphylococcus species are considered important members of the normal skin microbiota, in addition to being common pathogens in human and animal infections. In addition to S. aureus, other members of the genus are now widely-recognized as pathogens,...

  • Proceeding Paper
  • Open Access
1 Citations
1,411 Views
7 Pages

Combinations and Risks of Drug Interactions in Patients Admitted to a University Hospital in a Northeastern Brazilian State

  • Sara Maria Gomes Bié,
  • Felipe Lemos Esteves do Amaral,
  • Rafael Rodrigues Leite,
  • Sandriny Maria de Almeida Oliveira,
  • Maria Fernanda Bandeira da Silva,
  • Natália Bitu Pinto and
  • Sávio Benvindo Ferreira

A drug is defined as a substance capable of influencing biological functions through chemical reactions, either by agonism or antagonism, to achieve the desired therapeutic effect. During this process, several pharmacokinetic and pharmacodynamic even...

  • Abstract
  • Open Access
1 Citations
1,127 Views
2 Pages

Patients receiving hematopoietic stem-cell transplantation (HSCT) are prone to develop invasive infections due to disease and transplantation-related immunosuppression [...]

  • Abstract
  • Open Access
1,219 Views
2 Pages

Etiological Spectrum and Antimicrobial Resistance of Most Frequently Isolated Pathogens, Associated with Urinary Tract Infections in Ambulatory Patients

  • Viktoriya Snegarova,
  • Neli Ermenlieva,
  • Denis Nyazi,
  • Marina Miroshnikova,
  • Stoyan Stoyanov and
  • Temenuga Stoeva

Introduction: Urinary tract infections (UTIs) are one of the most common infections both in the community and in the hospital setting. Aim: The aim of this study is to investigate the etiological spectrum and antimicrobial resistance of the most freq...

  • Abstract
  • Open Access
1,694 Views
2 Pages

Experience with HB&L Uroquattro Instrument for Rapid Diagnosis of Urinary Tract Infections in Ambulatory Patients

  • Viktoriya Snegarova,
  • Neli Ermenlieva,
  • Marina Miroshnikova,
  • Stoyan Stoyanov and
  • Temenuga Stoeva

Urinary tract infections (UTIs) are one of the most common community and hospital-acquired infections. Rapid diagnosis and adequate etiological therapy are factors with direct impacts on the morbidity and mortality associated with these infections. T...

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Med. Sci. Forum - ISSN 2673-9992