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Gels, Volume 11, Issue 12

December 2025 - 86 articles

Cover Story: Gelatin-based hydrogels are promising for pharmaceutical and biomedical applications. However, their thermo-sensitivity often restricts practical use. Low-molecular-weight gelatin (LMWG) was obtained through controlled degradation of gelatin with hydroxylamine, and hydrogels were prepared by crosslinking with genipin. LMWG exhibited superior processability, remaining liquid at room temperature, and LMWG-genipin hydrogels showed higher swelling capacity, increased porosity, and improved flexibility without loss of mechanical integrity. Rheological analysis confirmed differences in thermo-sensitivity, and cytocompatibility assays demonstrated low toxicity and proliferation of cells on the materials. The combination of molecular weight modulation and crosslinking by genipin provides an effective strategy to develop gelatin-based hydrogels. View this paper
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Articles (86)

  • Article
  • Open Access
226 Views
14 Pages

Study on the Structure, Thermal Properties and Antibacterial Properties of Phosphorus-Modified PVA/TiO2 Composite Films

  • Alina-Mirela Ipate,
  • Diana Serbezeanu,
  • Ioana-Antonia Iftimie,
  • Gabriela Lisa,
  • Cristina-Mihaela Rîmbu and
  • Tăchiță Vlad-Bubulac

18 December 2025

Phosphorus-modified poly(vinyl alcohol) (PVA) has recently gained increasing attention as a functional polymeric matrix suitable for gel-based systems, owing to its biocompatibility, film-forming ability, and capacity to develop semi-interpenetrating...

  • Article
  • Open Access
202 Views
23 Pages

Synergistic Effect of Aminated Sodium Alginate Composite Material on Selective Adsorption of Sb: Experimental and Density Functional Theory Study

  • Lan Yang,
  • Pingshu Wang,
  • Xin Sun,
  • Kai Li,
  • Meijie Ren,
  • Fansong Liu,
  • Fawei Tang,
  • Ping Ning and
  • Yimin Huang

18 December 2025

Pollution by Sb, which is widely used in industry and agriculture, poses serious threats to ecosystems. This study demonstrates, for the first time, that sodium alginate (ALG) modified by polyethyleneimine (PEI) has good adsorption capacity for Sb(II...

  • Article
  • Open Access
317 Views
15 Pages

A Novel Phenolic Resin Aerogel Modified by SiO2-ZrO2 for Efficient Thermal Protection and Insulation

  • Yifan Zhan,
  • Chunhui Zhang,
  • Liangjun Li,
  • Mengle Huang,
  • Sian Chen,
  • Yonggang Jiang,
  • Junzong Feng,
  • Yijie Hu and
  • Jian Feng

18 December 2025

Phenolic aerogel holds great promise for applications in thermal protection against ablation, and constructing inorganic–organic hybrid networks is an effective strategy to enhance its oxidation and ablation resistance. This study introduces a...

  • Article
  • Open Access
195 Views
15 Pages

From Vegetable Waste to By-Product: Rheological Analysis of a Potential High-Protein Vegetable Burger

  • Olga Mileti,
  • Francesco Filice,
  • Francesca R. Lupi,
  • Domenico Gabriele and
  • Noemi Baldino

18 December 2025

(1) Foods with attractive shapes have been receiving increasing interest from researchers, particularly for foods for children. The ability to particularize foods by imparting attractive aspects to nutritious and less attractive food ingredients, suc...

  • Article
  • Open Access
341 Views
21 Pages

Engineering Inhalable Carboxymethyl Chitosan-Swellable Microgels for Pulmonary Delivery of Charged Hydrophilic Molecules

  • David Encinas-Basurto,
  • Kiley McCombs,
  • Ernest L. Vallorz,
  • Maria F. Acosta,
  • Rick G. Schnellmann and
  • Heidi M. Mansour

17 December 2025

Swellable microparticles are a promising strategy for pulmonary drug delivery. They provide good aerosol performance in the dry state and enlarge after deposition in the lungs. In this study, we aimed to develop and characterize spray-dried micropart...

  • Article
  • Open Access
264 Views
17 Pages

17 December 2025

This study aimed to evaluate the effect of experimental bleaching gels containing chitosan and theobromine and compare their performance in terms of tooth surface roughness, microhardness, and colour change with the bleaching gels BioWhiten ProHome a...

  • Review
  • Open Access
514 Views
25 Pages

17 December 2025

Eutectogels, obtained from the combination of deep eutectic systems (DESs) or natural deep eutectic systems (NADESs) with polymers, represent a new class of sustainable soft materials. Combining the tunable properties of DESs, such as low volatility,...

  • Article
  • Open Access
422 Views
21 Pages

Camellia Saponin-Enhanced Sodium Alginate Hydrogels for Sustainable Fruit Preservation

  • Lisong Hu,
  • Hongdan Rao,
  • Borong Zhu,
  • Menghao Du,
  • Keqin Xu and
  • Haili Gao

16 December 2025

It is well known that food waste, especially perishable fruits, is one of the pressing issues worldwide, and as much as 50% of harvested fruits are wasted in developing countries as a result of poor preservation methods. Other traditional options suc...

  • Article
  • Open Access
247 Views
20 Pages

The Influence of Synthesis Parameters on the Properties of Dextran-Based Hydrogels for Colon-Targeted Antitumor Drug Delivery Part I: Room Temperature Synthesis of Dextran/Inulin Hydrogels for Colon-Targeted Antitumor Drug Delivery

  • Tamara Erceg,
  • Miloš Radosavljević,
  • Milorad Miljić,
  • Aleksandra Cvetanović Kljakić,
  • Sebastian Baloš,
  • Katarina Mišković Špoljarić,
  • Ivan Ćorić,
  • Ljubica Glavaš-Obrovac and
  • Aleksandra Torbica

16 December 2025

This research successfully developed novel hydrogels composed of methacrylated dextran and inulin for targeted drug delivery in colorectal cancer therapy. The formulation exploits the natural degradation of both biopolymers by the large intestine&rsq...

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Gels - ISSN 2310-2861