2026 February - 80 articles
Sub-Saharan Africa, a region marked by enormous social and health inequalities, has the largest population infected with HIV and Mycobacterium tuberculosis, which are considered the main risk factors for fungal infections. At the same time, sub-Sahar...
Monilinia laxa and Colletotrichum fioriniae are major fungal pathogens causing brown rot and anthracnose in stone fruits and shell fruits, leading to significant economic losses. Chemical fungicides are widely applied but can result in resistance dev...
The ascomycete fungus Clonostachys rosea is a promising biocontrol agent against root-knot nematodes. To develop a more effective and stable biocontrol strategy, we rationally constructed a co-culture system by partnering C. rosea with the plant grow...
Fusarium verticillioides is a significant agricultural pathogen and an emerging causative agent of invasive fusariosis in clinical settings. Fusarium species frequently exhibit resistance to available antifungal agents, yet the molecular mechanisms u...
Candidozyma auris is an emerging multidrug-resistant fungal pathogen associated with severe invasive infections and high mortality, particularly in healthcare environments. Its rapid global expansion and resistance to multiple antifungal classes pose...
“Unusual sporotrichosis”, a concept proposed in this review, refers to severe, extracutaneous, or anatomically atypical manifestations of sporotrichosis occurring in immunocompetent hosts and represents an underrecognized clinical subset...
Bats play a crucial role in the ecosystem. However, North American bat populations have experienced a dramatic decline since 2006 due to white-nose syndrome, a disease caused by Pseudogymnoascus destructans (Pd). This fungus can invade and damage the...
Amylocorticiales forms a well-supported clade within Agaricomycetes, Basidiomycota, and most of the species have resupinate basidiomes and cause brown rot on wood. It is one of the smallest orders of the basidiomycetes, with the species diversity and...
Vulvovaginal candidiasis (VVC) represents a widespread gynaecological challenge, affecting approximately 75% of women at some point during their reproductive years, with a significant subset progressing to recurrent forms (RVVC). Classical azoles and...
Tetranychus urticae is a globally important economic pest mite. Isaria cateniannulata can infect the mite through its conidial penetration of the cuticle, ultimately leading to host mortality; however, the immune mechanisms involving enzyme activity...
Genetically encoded biosensors represent cutting-edge biosensors due to their capabilities in real-time monitoring and precise control in living cells. However, the development of eukaryotic genetically encoded biosensors for new analytes is constrai...
Frequent strain degeneration during subcultivation, characterized by impaired sporulation and fruiting body formation, represents a major constraint in fungal agricultural production. Our study systematically investigated two naturally degenerated Le...
Rice blast, caused by Magnaporthe oryzae, severely threatens global rice production. Although the receptor-like cytoplasmic kinase OsRLCK118 positively regulates rice immunity, its downstream signaling mechanism remains unknown. To systematically ide...
Fungi regularly occur on spacecrafts, posing a serious risk to humans and equipment. In this study, we characterized how the model organism Aspergillus nidulans responds to low-intensity, short-duration proton irradiation designed to simulate a solar...
Morchella is a highly valued edible and medicinal fungus with significant nutritional and economic value. In recent years, with the development of artificial cultivation techniques, the planting area of Morchella has been expanding continuously, whil...
Boletaceae, a family of profound ecological influence and economic value, has been the subject of prolific taxonomic research over the past decade, with new taxa continually being discovered. In this study, Similiboletinus tomentopileatus gen. et sp....
Aspergillus flavus Link, 1809 is a pathogenic fungus widely present in the environment. It can infect plants and also acts as an opportunistic pathogen affecting humans and other animals. The aflatoxins (AFs), it produces, can cause cancers such as l...
Inonotus hispidus is an important medicinal and edible fungus within the “Sanghuang” category, featuring a broad host range and rapid fruiting body growth. However, its wild resources are currently threatened by overharvesting. Simultaneo...
The World Health Organization WHO considers fungal infections as a significant global risk that necessitates the development of new therapies. The arsenal of antifungals is limited, and the eukaryotic organization of fungi makes it difficult to find...
Elsinoe fawcettii is a devastating citrus pathogen worldwide, yet high-quality genomic resources are lacking, limiting insights into its adaptive mechanisms. Seventeen strains collected from 13 host species across 5 Chinese provinces were confirmed a...
To address the “fungus-forest conflict” in the edible mushroom industry and the challenge of resource utilization for bamboo substrate waste, this study focused on white Auricularia cornea, and cultivation systems were established with ba...
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The early diagnosis of invasive candidiasis remains challenging in immunocompromised and other high-risk patients, prompting interest in artificial intelligence models for assisting clinical decision-making. We conducted a PROSPERO-registered systema...
Molecular mechanisms determining pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi are poorly understood. Prior identification of the pathogenicity locus pat1 prompted a chromosome walking approach to elucidate gene function in this...
Exogenous genes are generally expressed by integration into the chromosomes of Pichia pastoris. However, systematic studies on the chromosomal position effect are lacking, and locations that are conducive to the high expression of foreign genes are r...
The IMMY cryptococcal antigen (CrAg) lateral flow assay (LFA) is a reliable diagnostic tool for Cryptococcus detection, but false-positive results may arise from procedural or reagent-related errors, underscoring careful operation of the assay to ens...
Sclerotium formation represents a critical transition phase in the life cycle of morel, shifting from vegetative growth to dormant structures. The capacity for sclerotium formation directly influences the yield and stability of artificial cultivation...
Ophiocordyceps xuefengensis is an important medicinal fungus with considerable pharmaceutical and economic value. However, its industrial and scientific utilization has been severely limited by the lack of an efficient genetic transformation system,...
Blueberry rust disease is caused by the fungal pathogen Pucciniastrum minimum (syn. Thekopsora minima). Despite its importance as a plant pathogen, there are relatively few published studies on P. minimum. This study investigated and refined methodol...
Candidozyma auris is an emerging multidrug-resistant yeast that readily contaminates healthcare environments, persisting on dry surfaces and enabling transmission and difficult-to-control outbreaks. A systematic review of environmental hygiene interv...
Cadmium (Cd) contamination in agricultural soils severely impairs plant growth, disrupts microbial communities, and threatens food safety due to its high toxicity and mobility. Conventional remediation methods are often expensive and environmentally...
The species Candidozyma auris (formerly known as Candida auris) can be subdivided into four major and two minor clades. It is considered an emerging multidrug-resistant pathogen that causes invasive outbreaks around the world. Therefore, the accurate...
Invasive fungal infections are frequent complications in patients with hematologic malignancies due to immunosuppression and intensive treatments. In Colombia, limited diagnostic availability, heterogeneous prescribing practices, and emerging antifun...
The presence of lithobionts has historically been associated with biodeterioration, posing significant challenges to the conservation of culturally and historically significant stone heritage. This perception stems from abundant evidence of their rol...
Monascus spp. are renowned for producing valuable Monascus azaphilone pigments (MonAzPs), yet their biosynthesis is intrinsically linked to the co-production of the mycotoxin citrinin, posing a significant safety challenge and limiting industrial app...
Pomegranate dieback is a disease whose etiology remains only partially understood. In this study, surveys were carried out in orchards located in the Apulia, Basilicata, and Veneto regions from 2016 to 2020 with the objective to identify pathogens in...
Oudemansiella raphanipes is a prized edible mushroom renowned for its “three-high, one-low” nutritional profile (high protein, fiber, vitamins; low fat). However, the stage-specific molecular dynamics governing its development and their p...
Excessive fertilizer use drives soil degradation and resource waste. This study investigates how arbuscular mycorrhizal fungi (AMF) formulations (powder vs. granular) optimize maize (Zea mays L.) yield, soil microbiome, and economic benefits under 50...
The majority of terrestrial plants can interact with arbuscular mycorrhizal fungi (AMF) to form symbiotic relationships. AMF colonization not only enhances the host plant’s uptake of mineral nutrients but also improves its tolerance to biotic a...
Fusarium wilt of banana, caused by Fusarium oxysporum f. sp. cubense (Foc), is a destructive vascular disease that seriously threatens global banana production. To investigate the contribution of histidine metabolism to Foc growth and pathogenicity,...
Disseminated cutaneous coccidioidomycosis (DCC) is an uncommon manifestation of Coccidioides infection resulting from hematogenous spread to the skin. While recurrence after treatment discontinuation has been reported in 17 to 50 percent of cases, as...
The fungal pathogen Metschnikowia bicuspidata causes “milky disease” in the Chinese mitten crab (Eriocheir sinensis), which poses substantial challenges to sustainable aquaculture development considering the current lack of effective trea...
Cordycepin is a key active component of Cordyceps militaris, but the molecular mechanism underlying temperature-regulated biosynthesis remains unclear. In this study, Cordyceps militaris strain KN-1 was used as experimental material, with low-tempera...
Species of the ascomycetous genus Cladobotryum (Hypocreales, Hypocreaceae) are ecologically and economically important mycoparasites that cause cobweb disease in cultivated and wild mushrooms. Despite their significance as fungal pathogens and produc...
Although RNA sequencing (RNA-seq) enables rapid transcriptome profiling, functional annotation of fungal transcriptomes remains challenging. Existing tools prioritize broad taxonomic coverage, and reference genomes are scarce for non-model species. T...
Protein phosphorylation modification plays a role in cells’ response to oxidative stress, a key factor leading to postharvest browning of Flammulina filiformis. However, the molecular mechanism by which protein phosphorylation contributes to po...
Soil alkalinization constitutes a significant abiotic stress factor that severely constrains global agricultural productivity. The application of alkali-tolerant endophytes represents a promising strategy for enhancing crop resilience. This study foc...
FLOCponics systems combine biofloc-based aquaculture with nutrient recycling and are considered sustainable for intensive aquaculture. However, fungal community dynamics in these systems and their links to water quality remain poorly understood. In t...
Sphingolipids are a class of amphipathic lipids characterized by a sphingoid base backbone, which can be classified into glycosphingolipids and sphingomyelins. They exhibit structural complexity and functional diversity, being widely distributed in e...
Recent advances in high-throughput sequencing technologies have significantly enhanced the accuracy of phylogenetic inference, enabling comprehensive genome-wide analyses. Fusarium fungi, which include numerous agriculturally and medically important...
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