Bioengineering, Volume 12, Issue 6

Motivated by illuminating the underlying mechanisms of preeclampsia, we develop a changepoint detection-based general and versatile methodology that can be applied to any experimental model, effectively addressing the challenges of high uncertainty p...

Accurate segmentation of cellular structures in whole slide images (WSIs) is essential for quantitative analysis in computational pathology. However, the complexity and scale of WSIs present significant challenges for conventional segmentation method...

Transcranial direct current stimulation (tDCS) is a safe, well-tolerated method of non-invasively eliciting cortical neuromodulation. It has gained recent interest, especially for its positive clinical outcomes in neurodegenerative diseases such as m...

Implantable telemetry biosensors have become powerful tools for continuous physiological monitoring with minimal animal perturbation. However, commercially available implants are relatively oversized for small animals such as mice and have limited tr...

The traditional bilateral pedicle screw system has been used for the treatment of various lumbar spine conditions including advanced degenerative disc disease. However, there is an ongoing need to develop more effective and less invasive techniques....

Significant challenges persist in diagnosing non-ischemic cardiomyopathies (NICMs) owing to early morphological overlap and subtle functional changes. While cardiac magnetic resonance (CMR) offers gold-standard structural assessment, current morpholo...

Unobtrusive in-vehicle measurement and the monitoring of physiological signals have recently attracted researchers in industry and academia as an innovative approach that can provide valuable information about drivers’ health and status. The ma...

This study aimed to develop a novel modular pedicle screw system incorporating an elliptical sleeve to conform the pedicle’s elliptical cross-section and enhance fixation strength with mechanical stability. The biomechanical evaluation was cond...

Unilateral vocal fold paralysis (UVFP) can lead to significant dysphonia. Medialization thyroplasty type 1 (TT1) is a common surgical intervention aiming at improving vocal quality by optimally positioning the paralyzed fold to generate the necessary...

(1) Background: Patients with mild cervical spondylotic myelopathy (CSM) who delay surgery risk progression. While PET evaluates spinal cord function, its cost and radiation limit its use. (2) Methods: In this prospective study, patients with mild ce...