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Biomolecules, Volume 12, Issue 6
June 2022 - 122 articles
Cover Story: Our review summarizes recent advances in nitric oxide (NO) signaling of glomerular podocytes. Podocytes are specialized epithelial cells that wrap around the glomerular capillaries and are integral to glomerular structure and function. NO is an intracellular and extracellular ubiquitous messenger molecule involved in various signaling pathways. NO bioavailability, a factor indicating the production and utilization of this molecule, is controlled by cell-specific nitric oxide synthases (NOSs) and oxidative inactivation. Changes in NO bioavailability influence the development of podocyte pathology. Understanding and further investigating NO signaling in glomerular cells could facilitate the design of novel strategies to prevent or manage health conditions that cause glomerular and kidney damage. View this paper
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Biomolecules - ISSN 2218-273XCreative Common CC BY license