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Biology, Volume 9, Issue 7

July 2020 - 39 articles

Cover Story: Mesenchymal stem cells (MSCs) have been considered a promising cell population for cell-based therapy and tissue regeneration. Recently, dental pulp stem cells (DPSCs) and stem cells from human exfoliated deciduous teeth (SHEDs) have been isolated, and have attracted substantial attention in terms of their clinical application because of their MSC-like qualities including robust self-renewal ability, multilineage differentiation potential, and immunomodulatory effects. In addition, various growth factors, extracellular vesicles, and epigenetic regulators which can facilitate the therapeutic potential of these cells have been identified, although their signaling interactions are still under investigation. Further clarification of the biological attributes of DPSCs and SHEDs and the development of safe and effective therapeutic approaches are needed to translate them into a clinical setting. View this paper.
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Articles (39)

  • Editorial
  • Open Access
7 Citations
2,635 Views
3 Pages

The Unknown Process Osseointegration

  • Nansi López-Valverde,
  • Javier Flores-Fraile and
  • Antonio López-Valverde

16 July 2020

Although it was already described more than fifty years ago, there is yet no in-depth knowledge regarding the process of osseointegration as far as its mechanism of action is concerned. It could be one of the body’s ways of reacting to a foreig...

  • Article
  • Open Access
4 Citations
3,424 Views
20 Pages

Impact of Cytokines and Phosphoproteins in Response to Chronic Joint Infection

  • Nicole Prince,
  • Julia A. Penatzer,
  • Matthew J. Dietz and
  • Jonathan W. Boyd

16 July 2020

The early cellular response to infection has been investigated extensively, generating valuable information regarding the mediators of acute infection response. Various cytokines have been highlighted for their critical roles, and the actions of thes...

  • Article
  • Open Access
21 Citations
5,389 Views
12 Pages

16 July 2020

Microalgae have a wide industrial potential because of their high metabolic diversity and plasticity. Selection of optimal cultivation methods is important to optimize multi-purpose microalgal biotechnologies. In this research, Chlorella sorokiniana...

  • Article
  • Open Access
31 Citations
4,541 Views
17 Pages

Peptide Profiling and Biological Activities of 12-Month Ripened Parmigiano Reggiano Cheese

  • Lisa Solieri,
  • Andrea Baldaccini,
  • Serena Martini,
  • Aldo Bianchi,
  • Valentina Pizzamiglio and
  • Davide Tagliazucchi

16 July 2020

Proteolysis degree, biological activities, and water-soluble peptide patterns were evaluated in 12 month-ripened Parmigiano Reggiano (PR) cheeses collected in different dairy farms and showing different salt and fat content. Samples classified in hig...

  • Article
  • Open Access
34 Citations
5,755 Views
22 Pages

Vegetation- and Environmental Changes on Non-Reclaimed Spoil Heaps in Southern Poland

  • Oimahmad Rahmonov,
  • Robert Krzysztofik,
  • Dorota Środek and
  • Justyna Smolarek-Lach

15 July 2020

The study focused on the changes in vegetation and soils on an undeveloped area of coal mine spoil heaps. The process of vegetation changes was evaluated on the basis of historical cartographic materials and fieldwork. Changes of vegetation in nearly...

  • Article
  • Open Access
21 Citations
3,466 Views
21 Pages

Potential Involvement of lncRNAs in the Modulation of the Transcriptome Response to Nodavirus Challenge in European Sea Bass (Dicentrarchus labrax L.)

  • Patricia Pereiro,
  • Raquel Lama,
  • Rebeca Moreira,
  • Valentina Valenzuela-Muñoz,
  • Cristian Gallardo-Escárate,
  • Beatriz Novoa and
  • Antonio Figueras

15 July 2020

Long noncoding RNAs (lncRNAs) are being increasingly recognised as key modulators of various biological mechanisms, including the immune response. Although investigations in teleosts are still lagging behind those conducted in mammals, current resear...

  • Article
  • Open Access
36 Citations
3,671 Views
11 Pages

15 July 2020

Skeletal muscle dysfunction and reduced physical capacity are characteristic features of chronic obstructive pulmonary disease (COPD). However, the search for a reliable biomarker to assess muscle health in CODP remains elusive. We analyzed the cours...

  • Article
  • Open Access
19 Citations
5,182 Views
12 Pages

Cytotoxic, Antioxidant, and Enzyme Inhibitory Properties of the Traditional Medicinal Plant Matthiola incana (L.) R. Br.

  • Maria Fernanda Taviano,
  • Natalizia Miceli,
  • Rosaria Acquaviva,
  • Giuseppe Antonio Malfa,
  • Salvatore Ragusa,
  • Deborah Giordano,
  • Guillermo Cásedas,
  • Francisco Les and
  • Víctor López

13 July 2020

Matthiola incana (L.) R. Br. (Brassicaceae) is widely cultivated for ornamental purposes and utilized as a medicinal plant. In the present work, the hydroalcoholic extract from the aerial parts of this species has been evaluated in different bioassay...

  • Review
  • Open Access
13 Citations
7,627 Views
11 Pages

12 July 2020

After the discovery in 1967 of plant glyoxysomes, aconitase, one the five enzymes involved in the glyoxylate cycle, was thought to be present in the organelles, and although this was found not to be the case around 25 years ago, it is still suggested...

  • Article
  • Open Access
18 Citations
5,438 Views
26 Pages

Development of an LDL Receptor-Targeted Peptide Susceptible to Facilitate the Brain Access of Diagnostic or Therapeutic Agents

  • Séverine André,
  • Lionel Larbanoix,
  • Sébastien Verteneuil,
  • Dimitri Stanicki,
  • Denis Nonclercq,
  • Luce Vander Elst,
  • Sophie Laurent,
  • Robert N. Muller and
  • Carmen Burtea

11 July 2020

Blood-brain barrier (BBB) crossing and brain penetration are really challenging for the delivery of therapeutic agents and imaging probes. The development of new crossing strategies is needed, and a wide range of approaches (invasive or not) have bee...

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Biology - ISSN 2079-7737