You are currently viewing a new version of our website. To view the old version click .

Biosensors, Volume 12, Issue 5

May 2022 - 102 articles

Cover Story: Our research incorporates the DNA–gold affinity interaction into an electrochemical nucleic-acid-based direct adsorption platform for the voltammetric detection of HOTAIR long noncoding RNA. Our platform utilizes highly specific and sensitive nanomaterials coupled with screen-printed gold electrodes. The assay features three main steps: (i) magnetic bead capture of HOTAIR targets, (ii) magnetic purification and isolation of targets, and (iii) direct adsorption and detection via interfacial affinity interaction. We demonstrate detection as low as 1 pM for samples containing designated proportions of synthetic HOTAIR spiked in buffer as well as healthy plasma samples. Our method shows huge potential in diagnostics due to its disposable, simple, inexpensive, easy-to-store, and portable design. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (102)

  • Brief Report
  • Open Access
17 Citations
3,955 Views
8 Pages

18 May 2022

Abnormal muscle tone and muscle weakness are related to gait asymmetry in stroke survivors. However, the internal muscle morphological changes that occur during walking remain unclear. To address this issue, this study investigated the muscle activit...

  • Review
  • Open Access
59 Citations
8,624 Views
24 Pages

AIE-Active Photosensitizers: Manipulation of Reactive Oxygen Species Generation and Applications in Photodynamic Therapy

  • Hao Yu,
  • Binjie Chen,
  • Huiming Huang,
  • Zhentao He,
  • Jiangman Sun,
  • Guan Wang,
  • Xinggui Gu and
  • Ben Zhong Tang

18 May 2022

Photodynamic therapy (PDT) is a non-invasive approach for tumor elimination that is attracting more and more attention due to the advantages of minimal side effects and high precision. In typical PDT, reactive oxygen species (ROS) generated from phot...

  • Article
  • Open Access
11 Citations
4,023 Views
13 Pages

An Aptamer-Functionalised Schottky-Field Effect Transistor for the Detection of Proteins

  • Thomas Farrow,
  • Siriny Laumier,
  • Ian Sandall and
  • Harm van Zalinge

18 May 2022

The outbreak of the coronavirus disease 2019 (COVID-19) in December 2019 has highlighted the need for a flexible sensing system that can quickly and accurately determine the presence of biomarkers associated with the disease. This sensing system also...

  • Article
  • Open Access
12 Citations
4,405 Views
18 Pages

Kinetics of Isothermal Dumbbell Exponential Amplification: Effects of Mix Composition on LAMP and Its Derivatives

  • Maud Savonnet,
  • Mathilde Aubret,
  • Patricia Laurent,
  • Yoann Roupioz,
  • Myriam Cubizolles and
  • Arnaud Buhot

18 May 2022

Loop-mediated isothermal amplification (LAMP) is an exponential amplification method of DNA strands that is more and more used for its high performances. Thanks to its high sensitivity and selectivity, LAMP found numerous applications from the detect...

  • Article
  • Open Access
26 Citations
4,724 Views
14 Pages

Analyzing Human Periodontal Soft Tissue Inflammation and Drug Responses In Vitro Using Epithelium-Capillary Interface On-a-Chip

  • Laidi Jin,
  • Ni Kou,
  • Fan An,
  • Zehang Gao,
  • Tian Tian,
  • Jianan Hui,
  • Chen Chen,
  • Guowu Ma,
  • Hongju Mao and
  • Huiying Liu

18 May 2022

The gingival epithelium–capillary interface is a unique feature of periodontal soft tissue, preserving periodontal tissue homeostasis and preventing microorganism and toxic substances from entering the subepithelial tissue. However, the functio...

  • Article
  • Open Access
12 Citations
4,080 Views
10 Pages

Double Competitive Immunodetection of Small Analyte: Realization for Highly Sensitive Lateral Flow Immunoassay of Chloramphenicol

  • Dmitriy V. Sotnikov,
  • Lyubov V. Barshevskaya,
  • Anastasia V. Bartosh,
  • Anatoly V. Zherdev and
  • Boris B. Dzantiev

17 May 2022

A new scheme of reagents interaction for lateral flow immunoassay (LFIA) is proposed, which combines the features of competitive and sandwich assay and provides highly sensitive detection of low-molecular-weight analytes. Namely, the antigen in the s...

  • Review
  • Open Access
21 Citations
5,383 Views
33 Pages

17 May 2022

Hepatocellular carcinoma (HCC) is the sixth most commonly malignant tumor and the third leading cause of cancer-related death in the world, and the early diagnosis and treatment of patients with HCC is core in improving its prognosis. The early diagn...

  • Article
  • Open Access
13 Citations
5,477 Views
19 Pages

Solving Color Reproducibility between Digital Devices: A Robust Approach of Smartphones Color Management for Chemical (Bio)Sensors

  • Pablo Cebrián,
  • Leticia Pérez-Sienes,
  • Isabel Sanz-Vicente,
  • Ángel López-Molinero,
  • Susana de Marcos and
  • Javier Galbán

17 May 2022

In the past twelve years, digital image colorimetry (DIC) on smartphones has acquired great importance as an alternative to the most common analytical techniques. This analysis method is based on fast, low-cost, and easily-accessible technology, whic...

  • Article
  • Open Access
18 Citations
5,913 Views
12 Pages

Bead Number Effect in a Magnetic-Beads-Based Digital Microfluidic Immunoassay

  • Wensyang Hsu,
  • Yu-Teng Shih,
  • Meng-Shiue Lee,
  • Hong-Yuan Huang and
  • Wan-Ning Wu

16 May 2022

In a biomedical diagnosis with a limited sample volume and low concentration, droplet-based microfluidics, also called digital microfluidics, becomes a very attractive approach. Previously, our group developed a magnetic-beads-based digital microflui...

of 11

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Biosensors - ISSN 2079-6374