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Biosensors, Volume 12, Issue 4

April 2022 - 73 articles

Cover Story: To manage and control the spread of the infection, a widely available and highly usable sensor for a sensitive and specific assay of the virus plays a fundamental role. In this study, we developed an optical sensor based on an imprinted photonic crystal film (IPCF) for the quick, simple, and cost-effective detection of SARS-CoV-2 spike protein in artificial saliva. Our IPCF sensor enabled label-free and highly sensitive detection with a smartphone-equipped optical setup. Specific and quantitative detection of the spike protein was successfully achieved, with a low detection limit of 429 fg/mL. In addition, it costs less than USD 1 for one IPCF to be used for diagnosis. Thus, the developed IPCF has the potential to provide a widely available and highly usable sensor. View this paper
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Articles (73)

  • Article
  • Open Access
36 Citations
6,148 Views
11 Pages

18 April 2022

Exosomes (30–100 nm in diameter) are a group of cell-derived membrane vesicles, packaged as valuable cargo with lipid, proteins, and genetic materials from their parent cells. With the increasing interest in exosomes for diagnostic and therapeu...

  • Article
  • Open Access
10 Citations
5,613 Views
12 Pages

Application of Self-Assembly Nanoparticles Based on DVDMS for Fenton-Like Ion Delivery and Enhanced Sonodynamic Therapy

  • Jinqiang Liu,
  • Shiying Fu,
  • Jiaxuan Xie,
  • Jianzhong Zhang,
  • Jintao Pan,
  • Chengchao Chu,
  • Gang Liu and
  • Shenghong Ju

18 April 2022

Upon harnessing low-intensity ultrasound to activate sonosensitizers, sonodynamic therapy (SDT) induces cancer cell death through the reactive oxygen species (ROS) mediated pathway. Compared with photodynamic therapy (PDT), SDT possesses numerous adv...

  • Review
  • Open Access
23 Citations
6,403 Views
21 Pages

17 April 2022

Two-dimensional quantum dots (2D-QDs) derived from two-dimensional sheets have received increasing interest owing to their unique properties, such as large specific surface areas, abundant active sites, good aqueous dispersibility, excellent electric...

  • Review
  • Open Access
26 Citations
8,130 Views
30 Pages

A Review on Flexible Electrochemical Biosensors to Monitor Alcohol in Sweat

  • Nuna G. Costa,
  • Joana C. Antunes,
  • Antonio J. Paleo and
  • Ana M. Rocha

16 April 2022

The continued focus on improving the quality of human life has encouraged the development of increasingly efficient, durable, and cost-effective products in healthcare. Over the last decade, there has been substantial development in the field of tech...

  • Review
  • Open Access
22 Citations
6,033 Views
27 Pages

16 April 2022

Thrombin plays a central role in hemostasis and its imbalances in coagulation can lead to various pathologies. It is of clinical significance to develop a fast and accurate method for the quantitative detection of thrombin. Electrochemical aptasensor...

  • Review
  • Open Access
55 Citations
7,894 Views
21 Pages

Nanozymes with Multiple Activities: Prospects in Analytical Sensing

  • Xiangheng Niu,
  • Bangxiang Liu,
  • Panwang Hu,
  • Hengjia Zhu and
  • Mengzhu Wang

16 April 2022

Given the superiorities in catalytic stability, production cost and performance tunability over natural bio-enzymes, artificial nanomaterials featuring enzyme-like characteristics (nanozymes) have drawn extensive attention from the academic community...

  • Article
  • Open Access
17 Citations
5,228 Views
16 Pages

15 April 2022

This paper proposes a rapid, label-free, and non-invasive approach for identifying murine cancer cells (B16F10 melanoma cancer cells) from non-cancer cells (C2C12 muscle cells) using machine-learning-assisted Raman spectroscopic imaging. Through quic...

  • Article
  • Open Access
10 Citations
3,143 Views
10 Pages

15 April 2022

A simple, selective, and quantitative platform for point-of-care diagnostic of COVID-19 is urgently needed as a complement in areas where resources are currently relatively scarce. To meet the needs of early diagnosis and intervention, a proof-of-con...

  • Communication
  • Open Access
28 Citations
5,407 Views
11 Pages

15 April 2022

In emergency medicine, the lactate level is commonly used as an indicator of the severity and response to the treatment of hypoperfusion-related diseases. Clinical lactate measurements generally require 3 h for clinical determination. To improve the...

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Biosensors - ISSN 2079-6374