Advances in Amplification Methods for Biosensors

Dear Colleagues,

Today, there is a rapidly growing demand for sensitive and selective biosensors in various domains, including environment monitoring such as (waste)water control, detection of pollution for personal/public safety, agricultural/food safety and quality control, veterinary and medical diagnostics, etc. For these applications, the main challenge remains to detect a minute amount of analytes in complex samples. Thus, recent biosensors based on the biomolecular recognition between analyte targets and relevant probes (antibodies, aptamers, molecular imprinted polymers (MIP), etc.) require the use of amplification methods to produce a measurable signal. The COVID-19 pandemic is a perfect demonstration with the need of (nucleic acids) amplification methods for the detection of SARS-CoV2 virus (RT-PCR, RT-LAMP, ELISA, etc.).

Therefore, this Special Issue of Biosensors will highlight recent advances in the design and development of novel amplification methods to improve the performance of biosensors. All the potential analyte targets will be considered ranging from molecules (ions, pesticides, hormones, antibiotics, endocrine disruptors, miRNA, proteins, biomarkers, etc.) to larger objects (viruses, spores, fungus, bacteria, cancer cells, etc.). Biosensors based on optical, electrochemical, chemiluminescence, fluorescence, resonant or mechanical transduction methods are encouraged. Finally, the amplification methods are not restricted: nucleic acid amplification (PCR, LAMP, RCA, NASBA, HCR, etc.) or logic gate circuits, enzymatic amplification (enzymes, DNAzymes, CRISPR, etc.), nanostructure-based amplification (nanoparticles, nanotubes, nanovesicles, MEMS/NEMS, nanosensors, etc.), as well as combined strategies implying several amplifications.

Dr. Arnaud Buhot
Guest Editor

If you want to learn more information or need any advice, you can contact the Special Issue Editor Jessica Zhou via directly.

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.