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Journal of Functional Biomaterials, Volume 9, Issue 1

March 2018 - 25 articles

Cover Story: Beyond being the repository of genetic information, DNA is playing an increasingly important role as a building block for molecular electronics. Its inherent structural and molecular recognition properties render it a leading candidate for molecular electronics applications. The structural stability, diversity, and programmability of DNA provide overwhelming freedom for the design and fabrication of molecular-scale devices. In the past two decades, DNA has therefore attracted enormous attention in the field of molecular electronics. This review gives a brief survey of the recent experimental progress in DNA-based single-molecule electronics with special focus on single-molecule conductance and I–V characteristics of individual DNA molecules. View this paper.
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Articles (25)

  • Review
  • Open Access
441 Citations
25,026 Views
26 Pages

Bioactive Glasses: Where Are We and Where Are We Going?

  • Francesco Baino,
  • Sepideh Hamzehlou and
  • Saeid Kargozar

Bioactive glasses caused a revolution in healthcare and paved the way for modern biomaterial-driven regenerative medicine. The first 45S5 glass composition, invented by Larry Hench fifty years ago, was able to bond to living bone and to stimulate ost...

  • Feature Paper
  • Review
  • Open Access
262 Citations
17,725 Views
33 Pages

Bioactive Glasses: From Parent 45S5 Composition to Scaffold-Assisted Tissue-Healing Therapies

  • Elisa Fiume,
  • Jacopo Barberi,
  • Enrica Verné and
  • Francesco Baino

Nowadays, bioactive glasses (BGs) are mainly used to improve and support the healing process of osseous defects deriving from traumatic events, tumor removal, congenital pathologies, implant revisions, or infections. In the past, several approaches h...

  • Feature Paper
  • Article
  • Open Access
33 Citations
11,376 Views
10 Pages

First Results of a New Vacuum Plasma Sprayed (VPS) Titanium-Coated Carbon/PEEK Composite Cage for Lumbar Interbody Fusion

  • Sven Hoppe,
  • Christoph E. Albers,
  • Tarek Elfiky,
  • Moritz C. Deml,
  • Helena Milavec,
  • Sebastian F. Bigdon and
  • Lorin M. Benneker

The aim of this study was to assess the performance of a new vacuum plasma sprayed (VPS) titanium-coated carbon/polyetheretherketone (PEEK) cage under first use clinical conditions. Forty-two patients who underwent a one or two segment transforaminal...

  • Feature Paper
  • Review
  • Open Access
463 Citations
31,012 Views
14 Pages

Three-dimensional printing has significant potential as a fabrication method in creating scaffolds for tissue engineering. The applications of 3D printing in the field of regenerative medicine and tissue engineering are limited by the variety of biom...

  • Feature Paper
  • Review
  • Open Access
85 Citations
12,492 Views
32 Pages

A Critical Review on Metallic Glasses as Structural Materials for Cardiovascular Stent Applications

  • Mehdi Jafary-Zadeh,
  • Gideon Praveen Kumar,
  • Paulo Sergio Branicio,
  • Mohsen Seifi,
  • John J. Lewandowski and
  • Fangsen Cui

Functional and mechanical properties of novel biomaterials must be carefully evaluated to guarantee long-term biocompatibility and structural integrity of implantable medical devices. Owing to the combination of metallic bonding and amorphous structu...

  • Feature Paper
  • Article
  • Open Access
7 Citations
8,208 Views
19 Pages

Antimicrobial Monomers for Polymeric Dental Restoratives: Cytotoxicity and Physicochemical Properties

  • Diane R. Bienek,
  • Stanislav A. Frukhtbeyn,
  • Anthony A. Giuseppetti,
  • Ugochukwu C. Okeke and
  • Drago Skrtic

A trend for the next generation of polymeric dental restoratives is to incorporate multifunctional capabilities to regulate microbial growth and remineralize tooth surfaces. Polymerizable 2-(methacryloyloxy)-N-(2-(methacryloyloxy)ethyl)-N,N-dimethyle...

  • Article
  • Open Access
13 Citations
8,600 Views
10 Pages

Electron Beam Immobilization of Novel Antimicrobial, Short Peptide Motifs Leads to Membrane Surfaces with Promising Antibacterial Properties

  • André Reinhardt,
  • Isabell Thomas,
  • Julie Schmauck,
  • Ralf Giernoth,
  • Agnes Schulze and
  • Ines Neundorf

In this study, the efficacy of electron beam irradiation versus chemical coupling for yielding polyethersulfone (PES) membranes with antibacterial properties was investigated. For the surface coating, a recently discovered lead compound, IL-KKA, comp...

  • Feature Paper
  • Review
  • Open Access
41 Citations
9,777 Views
15 Pages

Modulation of Osteoclast Interactions with Orthopaedic Biomaterials

  • Chris Steffi,
  • Zhilong Shi,
  • Chee Hoe Kong and
  • Wilson Wang

Biomaterial integration in bone depends on bone remodelling at the bone-implant interface. Optimal balance of bone resorption by osteoclasts and bone deposition by osteoblasts is crucial for successful implantation, especially in orthopaedic surgery....

  • Feature Paper
  • Review
  • Open Access
407 Citations
31,027 Views
16 Pages

Novel Biomaterials Used in Medical 3D Printing Techniques

  • Karthik Tappa and
  • Udayabhanu Jammalamadaka

The success of an implant depends on the type of biomaterial used for its fabrication. An ideal implant material should be biocompatible, inert, mechanically durable, and easily moldable. The ability to build patient specific implants incorporated wi...

  • Feature Paper
  • Review
  • Open Access
25 Citations
10,257 Views
15 Pages

Magnetic resonance imaging (MRI) is the most powerful tool for deep penetration and high-quality 3D imaging of tissues with anatomical details. However, the sensitivity of the MRI technique is not as good as that of the radioactive or optical imaging...

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J. Funct. Biomater. - ISSN 2079-4983