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Journal of Clinical Medicine, Volume 14, Issue 3

February-1 2025 - 379 articles

Cover Story: This study compares the clinical outcomes of zygomatic and subperiosteal implants, focusing on implant survival, soft tissue management, and postoperative complications over a five-year follow-up. Methods: A retrospective cohort study analyzed 150 patients divided into two groups based on the type of implant they had received. Zygomatic implants were assessed for immediate functional loading, procedural efficiency, and complications. Subperiosteal implants were evaluated for their customized design, keratinized mucosa integration, and adaptation to severe anatomical limitations. Conclusions: Zygomatic implants excel in immediate functional loading and allow for reduced procedural time but require advanced surgical expertise to mitigate the anatomical risks. Subperiosteal implants offer a safer, customizable solution, particularly in anatomically complex cases. View this paper
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Articles (379)

  • Review
  • Open Access
1 Citations
1,943 Views
14 Pages

6 February 2025

Background/Objectives: Dysregulation of Mood, Energy, and Social Rhythms Syndrome (DYMERS) characterizes the poor regulation of biological (sleep/waking), social, and behavioral rhythms that affected the level of burnout in healthcare professionals d...

  • Article
  • Open Access
1,877 Views
13 Pages

Imaging Findings of Human Papillomavirus-Positive and Human Papillomavirus-Negative Oropharyngeal Squamous Cell Carcinoma Associated with Recurrence

  • Taketo Suto,
  • Masaya Kawaguchi,
  • Hiroki Kato,
  • Hirofumi Shibata,
  • Takenori Ogawa,
  • Tomohiro Ando,
  • Yoshifumi Noda,
  • Fuminori Hyodo and
  • Masayuki Matsuo

6 February 2025

Objectives: This study aimed to compare the imaging findings associated with the recurrence of HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma (OPSCC). Methods: In total, 68 patients (51 men; mean age, 64.4 years; age range, 41&nd...

  • Article
  • Open Access
2 Citations
2,088 Views
16 Pages

A Longitudinal Cohort Assessing the Carotid Intima-Media Thickness Progression and Cardiovascular Risk Factors in a Rural Black South African Community

  • Given R. Mashaba,
  • Wendy N. Phoswa,
  • Sogolo L. Lebelo,
  • Solomon S. R. Choma,
  • Eric Maimela and
  • Kabelo Mokgalaboni

6 February 2025

Background: Diabetes mellitus [DM) is a fast-increasing non-communicable disease in South Africa, with a prevalence of 11.3%. The present study aimed to longitudinally investigate the association of carotid intima-media thickness [CIMT) progression a...

  • Article
  • Open Access
2 Citations
2,759 Views
14 Pages

Immune Checkpoint Inhibitor in Hepatocellular Carcinoma: Response Rates, Adverse Events, and Predictors of Response

  • Shekhar Swaroop,
  • Sagnik Biswas,
  • Shubham Mehta,
  • Arnav Aggarwal,
  • Umang Arora,
  • Samagra Agarwal,
  • Amitkumar Chavan,
  • Baibaswata Nayak and
  • Shalimar

6 February 2025

Background/Objectives: Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy. Barcelona Clinic Liver Cancer (BCLC) guidelines recommend antiangiogenic agents with immune checkpoint inhibitors as first-line therapy for advanced...

  • Article
  • Open Access
1,181 Views
12 Pages

Analysis of Early Post-Radiation Surgical Management of Metastatic Spinal Tumors

  • Sang Yun Seok,
  • Jae Hwan Cho,
  • Hyung Rae Lee,
  • Jae Woo Park,
  • Jin Hoon Park,
  • Dong-Ho Lee,
  • Chang Ju Hwang and
  • Sehan Park

6 February 2025

Background/Objectives: Radiotherapy is one of the various treatment options for patients with metastatic spinal tumors (MST). However, it is difficult to say that this is definitely an optimal treatment for MST, and there are several patients who nee...

  • Article
  • Open Access
2,935 Views
13 Pages

Early Sacral Neuromodulation: A Promising Opportunity or an Overload for Patients with a Recent Spinal Cord Injury? A Cross-Sectional Study

  • Sophina Bauer,
  • Lukas Grassner,
  • Doris Maier,
  • Ludwig Aigner,
  • Lukas Lusuardi,
  • Julia Peters,
  • Orpheus Mach,
  • Karin Roider,
  • Evelyn Beyerer and
  • Michael Kleindorfer
  • + 3 authors

6 February 2025

Background: A solid rationale exists for early sacral neuromodulation in the form of causal therapy that improves neurogenic lower urinary tract dysfunction after complete spinal cord injury. However, the short and early time frame for minimally inva...

  • Review
  • Open Access
1,671 Views
13 Pages

Chemotherapy with Alkylating Agents and Dental Anomalies in Children: A Systematic Review

  • Patrizia Gallenzi,
  • Angela Malatesta,
  • Edoardo Staderini and
  • Federica Guglielmi

6 February 2025

The aim of the systematic review is to analyze the type and the prevalence of dental side effects among cancer survivors treated with alkylating agents (AAs) during pediatric age. Moreover, the study aimed to investigate the association between the d...

  • Article
  • Open Access
4 Citations
3,456 Views
18 Pages

6 February 2025

Background/Objectives: Autogenous palatal free gingival graft (FGG) harvesting presents challenges for patients due to the increased risk of postoperative morbidity related to a second intraoral surgical wound that heals with secondary intention. Thi...

  • Review
  • Open Access
4 Citations
5,653 Views
32 Pages

6 February 2025

Metabolic syndrome, a cluster of metabolic disorders comprising dyslipidemia, insulin resistance, elevated blood pressure, and abdominal obesity, is a silent epidemic that may lead to outcomes such as cardiovascular disease, diabetes, and cancer. Due...

  • Article
  • Open Access
1,629 Views
20 Pages

The Effect of the I-Arch on the Buccal Alveolar Crest in Comparison with the Traditional Archwire Sequence: A Randomized Controlled Clinical Trial

  • Salam Mouhamad Omar Nakawah,
  • Mohamed Hasan Youssef,
  • Ornella Rossi,
  • Giovanna Perrotti and
  • Tiziano Testori

6 February 2025

Background/Objectives: The nature, diameter, and cross-section of orthodontic archwires affect tooth movement and the surrounding alveolar bone. Researchers have explored different features of archwires to optimize treatment outcomes. In this context...

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J. Clin. Med. - ISSN 2077-0383