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Journal of Clinical Medicine, Volume 14, Issue 2

2025 January-2 - 361 articles

Cover Story: The human hand, a vital sensory and motor organ, plays a key role in movement, independence, and social interaction. Its loss profoundly impacts quality of life, often compounded by phantom limb pain (PLP) and neuroma pain (NP). Despite advances in myoelectric prosthetics, sensory feedback systems remain inadequate, limiting their acceptance and functionality. Targeted sensory reinnervation (TSR) emerges as a promising surgical innovation, redirecting sensory nerves from the hand to the residual limb, enabling spatially accurate sensory maps and reducing pain. This study introduces a novel upper-limb TSR technique, demonstrating its potential to restore tactile perception, enhance prosthetic integration, and improve patient outcomes. View this paper
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Articles (361)

  • Article
  • Open Access
1 Citations
2,900 Views
12 Pages

Safety and Outcomes of Percutaneous Dilatational Tracheostomy in Patients with Hematologic Malignancies: A Retrospective Cohort Study

  • Asaf Miller,
  • Roee Noy,
  • Omri Simchon,
  • Natalia Gvozdev and ,
  • Yotam Shkedy and
  • Danny Epstein
  • + 1 author+ 0 author

20 January 2025

Background/Objectives: Patients with hematologic malignancy (HM) often experience high rates of thrombocytopenia, thrombocytopathy, anemia, leukopenia, and coagulopathy, which can significantly increase the risk of procedural and postoperative compli...

(This article belongs to the Section Hematology)
  • Article
  • Open Access
7 Citations
2,857 Views
16 Pages

Screening for Subclinical Atherosclerosis in Patients with Familial Hypercholesterolemia: Insights and Implications

  • Muhammed Furkan Deniz,
  • Baris Guven,
  • Abdullah Omer Ebeoglu,
  • Omer Burak Gul and ,
  • Ali Nayir,
  • Pelinsu Ozkan,
  • Zubeyir Bulat,
  • Ibrahim Turk,
  • Ozlem Demirelce and
  • Umit Yasar Sinan
  • + 10 authors+ 5 authors

20 January 2025

Background/Objectives: Familial hypercholesterolemia (FH) is a monogenic dyslipidemia that leads to early cardiovascular events. Subclinical atherosclerosis refers to the formation of atheromatous plaques in arterial beds before any clinical events....

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
6 Citations
2,548 Views
14 Pages

High Geriatric Nutritional Risk Index Risk as a Predictor of Postoperative Complications and Early Mortality in Older Adult Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancies

  • Ming-Hung Wang,
  • Chien-Yu Chen,
  • Yu-Hung Lin,
  • Yueh-Wei Liu and ,
  • Yu-Yin Liu,
  • Wei-Feng Li,
  • Chang-Ting Lin,
  • Szu-Wei Huang,
  • Cheng-Hsi Yeh and
  • Shih-Min Yin
  • + 5 authors+ 0 author

20 January 2025

Introduction: Pancreaticoduodenectomy (PD) is a major surgery associated with significant morbidity and mortality, especially in older adult patients. Malnutrition is a common complication in these patients and is linked to poorer outcomes. This stud...

(This article belongs to the Section General Surgery)
  • Brief Report
  • Open Access
1 Citations
2,966 Views
7 Pages

Dialysis Patients’ Evaluation of Lung Edema at Home Using a Mobile Phone Tele-Ultrasound Application: A Pilot Study

  • Itamar Ben Shitrit,
  • Aviya Kedmi,
  • Khaled El Haj,
  • Amit Kosto and ,
  • Ofri Karni,
  • Sharon Einav,
  • Tomer Poleg,
  • Ariel Avraham Hasidim,
  • Noa Bineth and
  • Lior Fuchs
  • + 8 authors+ 3 authors

20 January 2025

Background: Home rehabilitation improves patient satisfaction and reduces the need for specialist consultations. Hemodialysis is a costly post-ICU service that requires frequent monitoring. Previous studies have demonstrated the feasibility and accur...

(This article belongs to the Section Respiratory Medicine)
  • Review
  • Open Access
20 Citations
12,021 Views
22 Pages

State of the Art of Primary PCI: Present and Future

  • Andrea Mignatti,
  • Julio Echarte-Morales,
  • Matteo Sturla and
  • Azeem Latib

20 January 2025

Primary percutaneous coronary intervention (PCI) has revolutionized the management of ST-elevation myocardial infarction (STEMI), markedly improving patient outcomes. Despite technological advancements, pharmacological innovations, and refined interv...

(This article belongs to the Special Issue Recent Advances in the Diagnosis and Treatment of Myocardial Infarction)
  • Article
  • Open Access
7 Citations
5,571 Views
26 Pages

Effects of Spinal Cord Stimulation in Patients with Small Fiber and Associated Comorbidities from Neuropathy After Multiple Etiologies

  • Ángeles Canós-Verdecho,
  • Ara Bermejo,
  • Beatriz Castel,
  • Rosa Izquierdo and ,
  • Ruth Robledo,
  • Elisa Gallach,
  • Teresa Sevilla,
  • Pilar Argente,
  • Ismael Huertas and
  • María Morales-Suarez-Varela
  • + 6 authors+ 1 author

20 January 2025

Objectives: The aim of this study was to evaluate the effects of spinal cord stimulation (SCS) on pain, neuropathic symptoms, and other health-related metrics in patients with chronic painful peripheral neuropathy (PN) from multiple etiologies. Metho...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
4 Citations
2,142 Views
14 Pages

Joint Analysis of Cardiovascular Control and Shear Wave Elastography to Determine Carotid Plaque Vulnerability

  • Vlasta Bari,
  • Beatrice Cairo,
  • Francesca Gelpi,
  • Fabiana Fancoli and ,
  • Nicoletta Curcio,
  • Giulia Matrone,
  • Paolo Righini,
  • Giovanni Nano,
  • Alberto Porta and
  • Daniela Mazzaccaro
  • + 5 authors+ 0 author

20 January 2025

Background/Objectives: Carotid artery stenosis (CAS) is one of the main causes of stroke, and the vulnerability of plaque has been proved to be a determinant. A joint analysis of shear wave elastography, a radiofrequency echo-based wall tracking tech...

(This article belongs to the Section Vascular Medicine)
  • Article
  • Open Access
5 Citations
2,978 Views
10 Pages

Utilization Trends of Glucose-Lowering Medications Among Adult Kidney Transplant Recipients with Type 2 Diabetes in the United States

  • Panupong Hansrivijit,
  • Helen Tesfaye,
  • Deborah J. Wexler,
  • Reza Abdi and ,
  • Elisabetta Patorno and
  • Julie M. Paik
  • + 1 author+ 0 author

20 January 2025

Background: To date, there are limited studies describing the use of glucose-lowering medications (GLMs) in adult kidney transplant recipients (KTRs), and the uptake of sodium glucose cotransporter-2 inhibitors (SGLT2is) and glucagon-like peptide-1 r...

(This article belongs to the Section Nephrology & Urology)
  • Case Report
  • Open Access
2,187 Views
11 Pages

Are We Ready for Pseudotumors in Total Ankle Arthroplasty? A Case Report

  • Federico Sgubbi,
  • Antonio Mazzotti,
  • Alberto Arceri,
  • Simone Ottavio Zielli and ,
  • Elena Artioli,
  • Laura Langone,
  • Marco Gambarotti and
  • Cesare Faldini
  • + 3 authors+ 0 author

20 January 2025

Background: Pseudotumors are defined as exuberant non-neoplastic inflammatory masses. This condition can be associated with hip and knee arthroplasty but has not been reported in Total Ankle Arthroplasty (TAA). This paper reports a pseudotumor that f...

(This article belongs to the Special Issue Foot and Ankle Surgery: Clinical Challenges and New Insights)
  • Article
  • Open Access
7 Citations
4,174 Views
16 Pages

Prediction Model for POstoperative atriaL fibrillAtion in caRdIac Surgery: The POLARIS Score

  • Fabrizio Rosati,
  • Massimo Baudo,
  • Cesare Tomasi,
  • Giacomo Scotti and ,
  • Sergio Pirola,
  • Giorgio Mastroiacovo,
  • Gianluca Polvani,
  • Gianluigi Bisleri,
  • Stefano Benussi and
  • Claudio Muneretto
  • + 6 authors+ 1 author

20 January 2025

Background: New-onset postoperative atrial fibrillation (POAF) is the most common complication after cardiac surgery, occurring approximately in one-third of the patients. This study considered all-comer patients who underwent cardiac surgery to buil...

(This article belongs to the Section Cardiovascular Medicine)
  • Article
  • Open Access
7 Citations
3,251 Views
15 Pages

Evaluation of Conventional and Combined Doppler Parameters in Preeclampsia: Diagnostic and Prognostic Insights

  • Gulsan Karabay,
  • Burak Bayraktar,
  • Zeynep Seyhanli,
  • Ahmet Arif Filiz and ,
  • Betul Tokgoz Cakir,
  • Gizem Aktemur,
  • Nazan Vanli Tonyali,
  • Recep Taha Agaoglu,
  • Gulcan Kocaoglu and
  • Kadriye Yakut Yucel
  • + 6 authors+ 1 author

20 January 2025

Background: The aim of this study was to examine the relationship between conventional and novel Doppler parameters, including cerebroplacental ratio (CPR), cerebral–placental–uterine ratio (CPUR), umbilical-to-cerebral ratio (UCR), and a...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
1 Citations
1,791 Views
13 Pages

Baseline Vitamin D Levels on Quality of Life and Pain Perception Among Patients with Chronic Pain with Long-Term Prescription Opioid Use: A Prospective Study

  • Gabija Laubner Sakalauskienė,
  • Indrė Stražnickaitė,
  • Sigutė Miškinytė,
  • Linas Zdanavičius and ,
  • Jūratė Šipylaitė and
  • Robertas Badaras
  • + 1 author+ 0 author

20 January 2025

Objectives: To investigate the correlation between baseline serum concentrations of 25-hydroxyvitamin D (25-OHD) and quality of life (QoL), as well as pain perception in patients with chronic pain with long-term prescription opioid usage before opioi...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
1 Citations
2,277 Views
11 Pages

Evolution of the Quality of Care in Patients with Decompensated Heart Failure in a Venezuelan Hospital

  • Yaneth Torres,
  • Daniel Benitez,
  • Zenaida Morillo,
  • Juan Salazar and ,
  • Julio Contreras-Velasquez and
  • Valmore Bermudez
  • + 1 author+ 0 author

20 January 2025

Background/Objectives: Several parameters have been proposed for the objective measurement of the quality of care (QoC) and breaches of care in patients with heart failure (HF). Therefore, the objective of this study was to evaluate the measures of Q...

(This article belongs to the Special Issue Acute and Chronic Heart Failure: Clinical Updates and Perspectives)
  • Review
  • Open Access
20 Citations
14,475 Views
19 Pages

Comprehensive Review of Lipid Management in Chronic Kidney Disease and Hemodialysis Patients: Conventional Approaches, and Challenges for Cardiovascular Risk Reduction

  • Erica Abidor,
  • Michel Achkar,
  • Ibrahim Al Saidi,
  • Tanvi Lather and ,
  • Jennifer Jdaidani,
  • Alaukika Agarwal and
  • Suzanne El-Sayegh
  • + 2 authors+ 0 author

20 January 2025

Background/Objectives: Lipid disorders are very prevalent in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD), leading to heightened cardiovascular risk. This review examines the effectiveness of lipid-lowering agents in...

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
2,181 Views
8 Pages

Endoscopic Resection of Large Non-Pedunculated Colonic Polyps Without Submucosal Injection Is Safe and Effective with Adequate Technique

  • Melis Gokce Celdir,
  • Gilles Jadd Hoilat,
  • Alp Serhat Kahveci,
  • Rami El Abiad and
  • Henning Gerke

20 January 2025

Background/Objectives: Endoscopic resection with lift polypectomy using submucosal injection (SI) for large non-pedunculated colorectal polyps is recommended to facilitate complete mucosal resection and decrease the risk of perforation; however, ther...

(This article belongs to the Special Issue Recent Advances in the Diagnosis and Treatment of Gastrointestinal Diseases)
  • Article
  • Open Access
4 Citations
7,516 Views
21 Pages

20 January 2025

Background/Objectives: Despite standard preoperative fasting guidelines, residual gastric content can persist in some patients, increasing the risk of aspiration pneumonitis. Multiple patient-specific factors may predict gastric content retention, bu...

(This article belongs to the Section Anesthesiology)
  • Brief Report
  • Open Access
1,567 Views
7 Pages

Impact of Earthquakes During COVID-19 Lockdown on the Pediatric Injury Pattern in the Zagreb Urban Area

  • Dino Bobovec,
  • Tomislav Žigman,
  • Josip Lovaković,
  • Goran Augustin and ,
  • Anko Antabak and
  • Ivan Dobrić
  • + 1 author+ 0 author

20 January 2025

Background/Objectives: Previous works on the epidemiology of pediatric trauma during the COVID-19 lockdown observed a decrease in pediatric surgical emergency consultations and fracture referrals. None of those works describes a unique situation in w...

(This article belongs to the Section Clinical Pediatrics)
  • Article
  • Open Access
2,109 Views
14 Pages

Retrospective Analysis of R-COMP Therapy in Patients with Diffuse Large B-Cell Lymphoma (DLBCL): Assessing the Impact of Sample Selection Bias

  • Chiara Romano,
  • Francesco Branda,
  • Nicola Petrosillo,
  • Annalisa Arcari and ,
  • Francesco Merli,
  • Michele Spina,
  • Giancarlo Ceccarelli,
  • Massimo Ciccozzi,
  • Fabio Scarpa and
  • Luigi Rigacci
  • + 5 authors+ 0 author

20 January 2025

Background: Retrospective studies are often criticized for their susceptibility to case selection bias compared to prospective studies, which include all patients consecutively and are thus less prone to such limitations. However, the larger sample s...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
8 Citations
4,485 Views
12 Pages

Predictive Value of the DETECT Algorithm for Pulmonary Arterial Hypertension in Systemic Sclerosis: Findings from an Italian Observational Study

  • Stefano Stano,
  • Claudia Iannone,
  • Carlo D’Agostino,
  • Maria Rosa Pellico and ,
  • Livio Urso,
  • Nicoletta Del Papa,
  • Roberto Caporali and
  • Fabio Cacciapaglia
  • + 3 authors+ 0 author

20 January 2025

Background/Objectives: Pulmonary arterial hypertension (PAH) is a complication of systemic sclerosis (SSc), and several screening algorithms have been proposed for the early detection of PAH in SSc. This study aimed to evaluate the predicting values...

(This article belongs to the Section Immunology & Rheumatology)
  • Article
  • Open Access
3 Citations
3,564 Views
12 Pages

Dispatcher-Assisted CPR in Italy: A Nationwide Survey of Current Practices and Future Challenges in Emergency Medical Communication Centers

  • Guglielmo Imbriaco,
  • Giacomo Sebastiano Canova,
  • Lorenzo Righi,
  • Sara Tararan and ,
  • Giorgia Di Mario and
  • Nicola Ramacciati
  • + 1 author+ 0 author

19 January 2025

Background/Objectives: Dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) is widely recognized as a critical intervention that significantly reduces no-flow time, improving survival rates in out-of-hospital cardiac arrests (OHCAs). This study...

(This article belongs to the Section Emergency Medicine)
  • Article
  • Open Access
5 Citations
1,791 Views
11 Pages

Imaging Retrospective Study Regarding the Variability of the Osseous Landmarks for IAN Block

  • Andrei Urîtu,
  • Ciprian Roi,
  • Alexandra Roi,
  • Alexandru Cătălin Motofelea and ,
  • Ioana Badea,
  • Doina Chioran and
  • Mircea Riviș
  • + 2 authors+ 0 author

19 January 2025

Background/Objectives: The aim of this study is to identify the most accurate and consistent landmarks for determining the precise location of the mandibular foramen (MF) and the mandibular ramus, suggesting appropriate adjustments to anesthesia tech...

(This article belongs to the Special Issue Oral and Maxillofacial Surgery: Current Updates and Perspectives)
  • Feature Paper
  • Article
  • Open Access
2,609 Views
16 Pages

Plasma Endothelin-1 Levels: Non-Predictors of Alzheimer’s Disease Reveal Age Correlation in African American Women

  • Irene A. Zagol-Ikapitte,
  • Mohammad A. Tabatabai,
  • Derek M. Wilus and
  • Donald J. Alcendor

19 January 2025

Background/Objectives: Alzheimer’s disease (AD) and related dementias (ADRD) disproportionately impact racial and ethnic minorities. Contributing biological factors that explain this disparity have been elusive. Moreover, non-invasive biomarker...

(This article belongs to the Section Brain Injury)
  • Article
  • Open Access
1 Citations
1,820 Views
12 Pages

Comparison of COVID-19 and Non-COVID-19 Tracheostomised Patients: Complications, Survival, and Mortality Risk Factors

  • Marta Mesalles-Ruiz,
  • Maitane Alonso,
  • Marc Cruellas,
  • Martí Plana and ,
  • Anna Penella,
  • Alejandro Portillo,
  • Víctor Daniel Gumucio,
  • Xavier González-Compta,
  • Manel Mañós and
  • Julio Nogués
  • + 5 authors+ 0 author

19 January 2025

Objectives: To compare the outcomes of tracheostomised COVID-19 patients with non-COVID-19 tracheostomised patients to identify factors influencing severity and mortality. Methods: A retrospective, single-centre cohort study was conducted on COVID-19...

(This article belongs to the Topic Acute Respiratory Distress Syndrome (ARDS): Personalized Therapies and Beyond, 2nd Edition)
  • Article
  • Open Access
3 Citations
3,518 Views
11 Pages

Three-Dimensional Posture Analysis-Based Modifications After Manual Therapy: A Preliminary Study

  • Fabio Scoppa,
  • Andrea Graffitti,
  • Alessio Pirino,
  • Jacopo Piermaria and ,
  • Federica Tamburella and
  • Marco Tramontano
  • + 1 author+ 0 author

19 January 2025

Background/Objectives: Manual therapies like Osteopathic Manipulative Treatment (OMT) and Gentle Touch Intervention (GTI) are widely employed for improving posture and spinal alignment, but their effects as measured using advanced technologies remain...

(This article belongs to the Special Issue Manual Therapy for the Prevention and Management of Musculoskeletal and Related Disorders across the Life Course)
  • Article
  • Open Access
1,822 Views
9 Pages

19 January 2025

Background: To compare tracheal temperature (TET) with nasopharyngeal temperature (TNP) in patients undergoing cardiac surgery using cardiopulmonary bypass (CPB). Methods: TET was measured using a thermistor in the cuff of an endotracheal tube and TN...

(This article belongs to the Section Anesthesiology)
  • Review
  • Open Access
9 Citations
17,329 Views
17 Pages

Neurogenic Orthostatic Hypotension in Parkinson Disease—A Narrative Review of Diagnosis and Management

  • Cristina Grosu,
  • Otilia Noea,
  • Alexandra Maștaleru,
  • Emilian Bogdan Ignat and
  • Maria Magdalena Leon

19 January 2025

Background: Neurogenic orthostatic hypotension (NOH) is a significant non-motor manifestation of Parkinson’s disease (PD), that substantially affects patient disability and has a powerful impact on the quality of life of PD patients, while also...

(This article belongs to the Special Issue Symptoms and Treatment of Parkinson’s Disease)
  • Article
  • Open Access
3,363 Views
14 Pages

Assessing the Impact of the Prone Position on Acute Kidney Injury

  • Eden Ezra,
  • Itai Hazan,
  • Dana Braiman,
  • Rachel Gaufberg and ,
  • Jonathan Taylor,
  • Adva Alyagon,
  • Amit Shira Babievb and
  • Lior Fuchs
  • + 3 authors+ 0 author

19 January 2025

Background: Prone positioning is a standard intervention in managing patients with severe acute respiratory distress syndrome (ARDS) and is known to improve oxygenation. However, its effects on other organs, particularly the kidneys, are less well un...

(This article belongs to the Section Intensive Care)
  • Article
  • Open Access
4 Citations
2,274 Views
19 Pages

Clinical Outcomes of Catheter Ablation for Atrial Fibrillation in Patients with Acute Decompensated Heart Failure

  • Yoshifumi Ikeda,
  • Ritsushi Kato,
  • Hitoshi Mori,
  • Kenta Tsutsui and ,
  • Kazuhisa Matsumoto,
  • Masataka Narita,
  • Wataru Sasaki,
  • Daisuke Kudo,
  • Naomichi Tanaka and
  • Kazuo Matsumoto
  • + 5 authors+ 0 author

19 January 2025

Background: The prognosis of acute decompensated heart failure (ADHF) and heart failure (HF) with atrial fibrillation (AF) has been dismal. This study was performed to investigate the clinical outcomes of catheter ablation (CA) performed in patients...

(This article belongs to the Special Issue Atrial Fibrillation and Its Complications: Preventive Strategies and Relative Evidence)
  • Article
  • Open Access
6 Citations
2,033 Views
11 Pages

Dental Rehabilitation After Microvascular Reconstruction of Segmental Jaw Defects: A Ten-Year Follow-Up

  • Katharina Zeman-Kuhnert,
  • Alexander J. Gaggl,
  • Gian B. Bottini,
  • Benjamin Walch and ,
  • Christoph Steiner,
  • Georg Zimmermann and
  • Christian Brandtner
  • + 2 authors+ 0 author

19 January 2025

Background/Objectives: Defects in maxillary and mandibular continuity are common in maxillofacial practice. They can occur after trauma, osteonecrosis, congenital jaw deformities, or surgical resection of benign or malignant tumours. Reconstruction w...

(This article belongs to the Special Issue Clinical Progress in Microsurgical Reconstruction)
  • Review
  • Open Access
10 Citations
4,513 Views
16 Pages

19 January 2025

A healthy lifestyle plays a key role for maintaining the cardiovascular health (CVH) status and prevent cardiovascular disease occurrence. In fact, a healthy lifestyle was included in the AHA Cardiovascular Health score (Life’s Simple 7 [LS7]),...

(This article belongs to the Special Issue Hypertension and Cardiovascular Disease: Clinical Updates and Perspectives)
  • Article
  • Open Access
2 Citations
2,840 Views
22 Pages

A Real-Life Study in Sequential Therapy for Severe Menopausal Osteoporosis

  • Oana-Claudia Sima,
  • Mihai Costachescu,
  • Mihaela Stanciu,
  • Claudiu Nistor and ,
  • Mara Carsote,
  • Denisa Tanasescu,
  • Florina Ligia Popa and
  • Ana Valea
  • + 3 authors+ 0 author

19 January 2025

Background: Teriparatide (TPT) acts against severe primary (postmenopausal) osteoporosis (MOP), and it requires continuation with another anti-resorptive drug to conserve or enhance the effects on fracture risk reduction. Objective: To analyse the se...

(This article belongs to the Special Issue Advances in Clinical Rheumatology)
  • Article
  • Open Access
1 Citations
2,855 Views
15 Pages

Unmet Needs in the Management of Chronic Kidney Disease-Associated Pruritus and the Characteristics of the Ideal Treatment: A Spanish Cross-Sectional Survey from a Multidisciplinary Perspective

  • Patricia De Sequera,
  • José M. Martínez-Sesmero,
  • Isabel Romo,
  • Ana Calvo and ,
  • Susana Aceituno,
  • Olga Ruiz-Andrés and
  • Juan C. Julián-Mauro
  • + 2 authors+ 0 author

19 January 2025

Objectives: Chronic kidney disease-associated pruritus (CKD-aP) is underdiagnosed and not fully understood by healthcare professionals, which leads to poor patient management and impacts patients’ quality of life (QoL). The aim of this study wa...

(This article belongs to the Section Nephrology & Urology)
  • Review
  • Open Access
33 Citations
11,208 Views
28 Pages

Revolutionizing Cardiology: The Role of Artificial Intelligence in Echocardiography

  • Bhanu Maturi,
  • Subash Dulal,
  • Suresh Babu Sayana,
  • Atif Ibrahim and ,
  • Manasa Ramakrishna,
  • Viswanath Chinta,
  • Ashwini Sharma and
  • Harish Ravipati
  • + 3 authors+ 0 author

19 January 2025

Background: Artificial intelligence (AI) in echocardiography represents a transformative advancement in cardiology, addressing longstanding challenges in cardiac diagnostics. Echocardiography has traditionally been limited by operator-dependent varia...

(This article belongs to the Section Cardiovascular Medicine)
  • Article
  • Open Access
4 Citations
2,969 Views
13 Pages

Diagnostic Cut-Off Values Based on Lipid Layer Pattern for Dry Eye Disease Subtypes Assessment

  • Belen Sabucedo-Villamarin,
  • Jacobo Garcia-Queiruga,
  • Hugo Pena-Verdeal,
  • Carlos Garcia-Resua and ,
  • Eva Yebra-Pimentel and
  • Maria J. Giraldez
  • + 1 author+ 0 author

19 January 2025

Background: The aim of the present study was to establish a cut-off value of the Lipid Layer Pattern (LLP) between participants with different subtypes of Dry Eye Disease (DED) including Deficient Dry Eye (ADDE), Evaporative Dry Eye (EDE), and Mixed...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
1,489 Views
12 Pages

19 January 2025

Background/objective: Low back pain (LBP) is the leading cause of disability worldwide, resulting in enormous socio-economic and personal consequences. Sensory profiles during the acute back pain stage will predict central sensitization symptoms in t...

(This article belongs to the Special Issue Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment)
  • Article
  • Open Access
11 Citations
8,456 Views
12 Pages

Tinea Capitis Induced by Barber Shaving: Isolation of Trichophyton tonsurans

  • Giampaolo Addari,
  • Marialuisa Corbeddu,
  • Cristina Mugheddu,
  • Mariangela Chessa and ,
  • Grazia Vivanet,
  • Caterina Ferreli and
  • Laura Atzori
  • + 2 authors+ 0 author

19 January 2025

Background/Objective: Tinea capitis is a common scalp fungal infection with significant implications for public health, particularly in regions where proper hygiene and access to healthcare are limited. Emerging evidence suggests that this disea...

(This article belongs to the Special Issue New Insights into Infectious Skin and Mucosal Diseases)
  • Case Report
  • Open Access
2,228 Views
9 Pages

Multilocular Thymic Cyst with High F18 Fluorodeoxyglucose Uptake and Rheumatoid Arthritis: A Case Report

  • Francesco Ferrante,
  • Camilla Poggi,
  • Anastasia Centofanti,
  • Rita Vaz Sousa and ,
  • Valerio Sebastianelli,
  • Antonio Pio Evangelista,
  • Francesco Mattoccia,
  • Beatrice Zacchini,
  • Tiziano De Giacomo and
  • Massimiliano Bassi
  • + 7 authors+ 2 authors

18 January 2025

Background: multilocular thymic cysts are uncommon acquired cysts in the anterior mediastinum caused by incomplete thymic involution. They may be associated with autoimmune diseases, such as rheumatoid arthritis and systemic sclerosis. Methods: a 61-...

(This article belongs to the Special Issue Multidisciplinarity in Thoraco-Pulmonary Diseases: Every Generation Needs a New Revolution. Insights from the XXII SIET National Meeting)
  • Article
  • Open Access
3 Citations
3,173 Views
14 Pages

Healthcare Professionals’ Perspectives on Sepsis Care Pathways—Qualitative Pilot Expert Interviews

  • Lea Draeger,
  • Carolin Fleischmann-Struzek,
  • Jutta Bleidorn,
  • Lena Kannengiesser and ,
  • Konrad Schmidt,
  • Christian Apfelbacher and
  • Claudia Matthaeus-Kraemer
  • + 2 authors+ 0 author

18 January 2025

Background/Objectives: Despite recent decades’ rapid advances in the management of patients with sepsis and septic shock, global sepsis mortality and post-acute sepsis morbidity rates remain high. Our aim was, therefore, to provide a first over...

(This article belongs to the Section Emergency Medicine)
  • Article
  • Open Access
6 Citations
5,933 Views
13 Pages

Diabetes Mellitus as a Risk Factor for Complicated Urinary Tract Infections in Kidney Transplant Recipients

  • Severins Krohmals,
  • Christophe de Terwangne,
  • Arnaud Devresse,
  • Eric Goffin and ,
  • Tom Darius,
  • Antoine Buemi,
  • Michel Mourad,
  • Hector Rodriguez-Villalobos and
  • Nada Kanaan
  • + 4 authors+ 0 author

18 January 2025

Background: Urinary tract infections (UTIs) are a common complication after kidney transplantation. The aim of this study was to evaluate the impact of pre-existing diabetes mellitus and post-transplant diabetes mellitus (PTDM) on the occurrence of p...

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
3 Citations
3,175 Views
26 Pages

18 January 2025

Background: The work main purposes were to identify the sources of problems and demands causing parental burnout and to specify the resources/support factors during the COVID-19 pandemic. The study was based on the Balance Theory of Risk and Support/...

(This article belongs to the Special Issue The Impact of the COVID-19 Emergency on the Quality of Life of the General Population, Part II)
  • Review
  • Open Access
2 Citations
5,247 Views
23 Pages

Advancing Insights into Pediatric Macular Diseases: A Comprehensive Review

  • Lucia Ambrosio,
  • Tatiana Perepelkina,
  • Abdelrahman M. Elhusseiny,
  • Anne B. Fulton and
  • Jose Efren Gonzalez Monroy

18 January 2025

Pediatric macular disorders are a diverse group of inherited retinal diseases characterized by central vision loss due to dysfunction and degeneration of the macula, the region of the retina responsible for high-acuity vision. Common disorders in thi...

(This article belongs to the Section Clinical Pediatrics)
  • Article
  • Open Access
2,741 Views
13 Pages

A Technique to Augment Arthroscopic Bankart Repair With or Without a Metal Block: A Comparison

  • Paul Vedrenne,
  • Mohamad K. Moussa,
  • Kévin Picard,
  • Thomas Bauer and
  • Alexandre Hardy

18 January 2025

Introduction: Arthroscopic Bankart repair (ABR) is associated with an increased failure rate over time. The Recenter implant, a metal block, is designed to reinforce capsulolabral repair. The aim of this study was to evaluate whether the addition of...

(This article belongs to the Special Issue Current Trends and Innovations in Arthroscopic Shoulder Surgery)
  • Article
  • Open Access
4 Citations
5,236 Views
19 Pages

Alcohol, Tobacco and Illicit Drug Use During Pregnancy in the Longitudinal BELpREG Cohort in Belgium Between 2022 and 2024

  • Sien Lenie,
  • Laure Sillis,
  • Karel Allegaert,
  • Annick Bogaerts and ,
  • Anne Smits,
  • Kristel Van Calsteren,
  • Jan Y. Verbakel,
  • Veerle Foulon and
  • Michael Ceulemans
  • + 4 authors+ 0 author

18 January 2025

Background/Objectives: Substance use during pregnancy is associated with adverse outcomes for both mother and child. This study aimed to determine the prevalence and determinants of alcohol, tobacco and illicit drug use before and during pregnancy in...

(This article belongs to the Special Issue Clinical Risks and Perinatal Outcomes in Pregnancy and Childbirth)
  • Article
  • Open Access
2 Citations
3,598 Views
19 Pages

18 January 2025

Background/Objectives: Sarcopenia, characterized by reduced muscle mass and strength, is associated with osteoarthritis (OA), particularly in middle-aged women, and may worsen postoperatively. Resistance exercise (RE) can resolve sarcopenia; however,...

(This article belongs to the Special Issue New Insights into Exercise Intervention for Aging and Geriatric Diseases: 2nd Edition)
  • Article
  • Open Access
4 Citations
2,382 Views
18 Pages

Prioritizing Patient Selection in Clinical Trials: A Machine Learning Algorithm for Dynamic Prediction of In-Hospital Mortality for ICU Admitted Patients Using Repeated Measurement Data

  • Emma Pedarzani,
  • Alberto Fogangolo,
  • Ileana Baldi,
  • Paola Berchialla and ,
  • Ilaria Panzini,
  • Mohd Rashid Khan,
  • Giorgia Valpiani,
  • Savino Spadaro,
  • Dario Gregori and
  • Danila Azzolina
  • + 5 authors+ 0 author

18 January 2025

Background: A machine learning prognostic mortality scoring system was developed to address challenges in patient selection for clinical trials within the Intensive Care Unit (ICU) environment. The algorithm incorporates Red blood cell Distribution W...

(This article belongs to the Section Intensive Care)
  • Systematic Review
  • Open Access
2 Citations
3,996 Views
13 Pages

The Role of Impella in Cardiogenic Shock Complicated by an Acute Myocardial Infarction: A Meta-Analysis

  • Kiarash Sassani,
  • Christian Waechter,
  • Styliani Syntila,
  • Julian Kreutz and ,
  • Birgit Markus,
  • Nikolaos Patsalis,
  • Davide Di Vece,
  • Bernhard Schieffer,
  • Christian Templin and
  • Georgios Chatzis
  • + 5 authors+ 0 author

18 January 2025

Background: Emerging evidence suggests the role of mechanical circulatory support (MCS) devices in the therapy of refractory cardiogenic shock (CS). However, largerandomized trials addressing the role of Impella in the therapy of infarct-associated C...

(This article belongs to the Section Cardiology)
  • Review
  • Open Access
1 Citations
3,808 Views
16 Pages

Challenges in Diagnosing Adolescent Goiter: A Case Report with Brief Literature Insights in Juvenile Desmoid-Type Fibromatosis of the Thyroid Gland

  • Giorgiana-Flavia Brad,
  • Iulius Jugănaru,
  • Delia-Maria Nicoară,
  • Alexandra-Cristina Scutca and ,
  • Meda-Ada Bugi,
  • Raluca Asproniu,
  • Alexandru-Daniel Chelu,
  • Diana-Georgiana Basaca,
  • Mărioara Corneanu and
  • Otilia Mărginean
  • + 5 authors+ 0 author

18 January 2025

The prevalence of goiter, thyroid nodules, and thyroid cancers in the pediatric population has increased. In some rare cases, local conditions such as juvenile desmoid-type fibromatosis (JDTF) can mimic specific thyroid pathology, complicating the di...

(This article belongs to the Special Issue New Insights into Head and Neck Surgery)
  • Review
  • Open Access
3 Citations
3,574 Views
14 Pages

18 January 2025

Background: Stereotactic biopsy of posterior fossa lesions, which are often inoperable, enables a safe trajectory and provides tissue samples for accurate diagnosis, which is crucial for correct treatment since the latest World Health Organization Cl...

(This article belongs to the Section Clinical Neurology)
  • Review
  • Open Access
13 Citations
6,758 Views
16 Pages

The Cell-Specific Effects of JAK1 Inhibitors in Ulcerative Colitis

  • Suzanne H. C. Veltkamp and
  • Philip W. Voorneveld

18 January 2025

JAK1 inhibitors have become an important addition to the therapeutic options for ulcerative colitis (UC), targeting key inflammatory pathways mediated by cytokines such as the IL-6 family, interferons, IL-2 family, IL-10 family, and G-CSF. However, n...

(This article belongs to the Special Issue New Directions for Treatment and Assessment of Ulcerative Colitis)
  • Review
  • Open Access
12 Citations
4,037 Views
19 Pages

18 January 2025

Background/Objectives: Tumor-infiltrating lymphocytes (TILs) play a crucial role in the tumor microenvironment (TME), influencing the progression, prognosis, and response to treatment in oral squamous cell carcinoma (OSCC) and its precursors, oral po...

(This article belongs to the Section Oncology)

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J. Clin. Med. - ISSN 2077-0383