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Journal of Clinical Medicine, Volume 10, Issue 12

June-2 2021 - 207 articles

Cover Story: Beyond the optimal management of the traditional Atherosclerotic cardiovascular diseases (ASCVD) risk factors, infections should be considered as an important non-classical risk factor to enable early diagnosis and appropriate treatment. We summarized the currently available evidence regarding the role of inflammation in ASCVD and the association between the particular infections and pathogens on the development and progression of ASCVD. We also speculated about the potential therapeutic implications of the anti-inflammatory and anti-infective drugs on ASCVD outcomes, including drugs routinely administered in patients with ASCVD and novel strategies aiming at residual risk reduction. Considering the emerging association between infections and ASCVD, it is crucial to determine the possible advantages of infection prevention and treatment in patients with ASCVD. View this paper
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Articles (207)

  • Article
  • Open Access
5 Citations
2,611 Views
11 Pages

In Vitro Development of a New Sponge-Based Delivery System for Intracanal Antimicrobial Administration in Endodontic Treatment

  • Ruíz-Piñón Manuel,
  • Gancedo-Gancedo Tania,
  • Seoane-Prado Rafael,
  • Pérez-Estévez Antonio,
  • Blanco-Méndez José,
  • Luzardo-Álvarez Asteria,
  • Castelo-Baz Pablo,
  • Lorenzo-Pouso Alejandro,
  • Álvarez-Novoa Pablo and
  • Martín-Biedma Benjamín

21 June 2021

This study aimed to evaluate the in vitro performance of collagen-based sponges as a drug delivery system for intracanal antimicrobial administration. Four groups of loaded collagen-based sponges (A, 0.3% w/v amoxicillin trihydrate: potassium clavula...

  • Article
  • Open Access
11 Citations
2,672 Views
10 Pages

Therapeutic Efficacy of Autologous Platelet Concentrate Injection on Macular Holes with High Myopia, Large Macular Holes, or Recurrent Macular Holes: A Multicenter Randomized Controlled Trial

  • Mirinae Kim,
  • Jae-Yon Won,
  • Seung-Yong Choi,
  • Minhee Kim,
  • Ho Ra,
  • Donghyun Jee,
  • Jin-Woo Kwon,
  • Kui-Dong Kang,
  • Young-Jung Roh and
  • Young-Gun Park
  • + 4 authors

21 June 2021

We aimed to evaluate the anatomical and functional outcomes of pars-plana vitrectomy (PPV) with or without autologous platelet concentrate (APC) injection in patients with recurrent macular holes (MHs), large MHs, or MHs with high myopia. This multic...

  • Article
  • Open Access
12 Citations
2,641 Views
7 Pages

B-Type Natriuretic Peptides and High-Sensitive Troponin I as COVID-19 Survival Factors: Which One Is the Best Performer?

  • Renato de Falco,
  • Maria Vargas,
  • Daniela Palma,
  • Marcella Savoia,
  • Anna Miscioscia,
  • Biagio Pinchera,
  • Martina Vano,
  • Giuseppe Servillo,
  • Ivan Gentile and
  • Giuliana Fortunato

21 June 2021

Increased concentrations of B-type natriuretic peptide (BNP), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity troponin I (HsTnI) in COVID-19 patients have already been reported. The aim of this study is to evaluate which of...

  • Article
  • Open Access
11 Citations
2,719 Views
6 Pages

21 June 2021

Antiphospholipid syndrome (APS) is associated with thrombotic events (tAPS) and/or obstetrical morbidity (oAPS), with persisting antiphospholipid antibodies (aPL). Despite an update of aPL in 2006, several patients had typical clinical events without...

  • Article
  • Open Access
6 Citations
2,259 Views
13 Pages

21 June 2021

Early allograft dysfunction (EAD) is a postoperative complication that may cause graft failure and mortality after liver transplantation. The objective of this study was to examine whether the preoperative serum uric acid (SUA) level may predict EAD....

  • Article
  • Open Access
9 Citations
3,420 Views
8 Pages

Carboxyhemoglobinemia in Critically Ill Coronavirus Disease 2019 Patients

  • Hina Faisal,
  • Syeda T. Ali,
  • Jiaqiong Xu,
  • Tariq Nisar,
  • Mahmoud Sabawi,
  • Eric Salazar and
  • Faisal N. Masud

21 June 2021

Carboxyhemoglobinemia is a common but a serious disorder, defined as an increase in carboxyhemoglobin level. Unfortunately, there are few data on carboxyhemoglobinemia in coronavirus disease 2019 (COVID-19) patients. Therefore, our study aimed to eva...

  • Article
  • Open Access
12 Citations
3,087 Views
12 Pages

The Addition of Transarterial Chemoembolization to Palliative Chemotherapy Extends Survival in Intrahepatic Cholangiocarcinoma

  • Simon Johannes Gairing,
  • Felix Thol,
  • Lukas Müller,
  • Felix Hahn,
  • Thomas Thomaidis,
  • Carolin Czauderna,
  • Fabian Bartsch,
  • Michael Bernhard Pitton,
  • Jens Uwe Marquardt and
  • Marcus-Alexander Wörns
  • + 5 authors

21 June 2021

Incidence and mortality of intrahepatic cholangiocarcinoma (iCCA) have been increasing continuously. Recent studies suggest that the combination of palliative chemotherapy (pCTX) and transarterial chemoembolization (TACE) improves overall survival (O...

  • Review
  • Open Access
32 Citations
10,292 Views
15 Pages

Incidence of Fat Embolism Syndrome in Femur Fractures and Its Associated Risk Factors over Time—A Systematic Review

  • Maximilian Lempert,
  • Sascha Halvachizadeh,
  • Prasad Ellanti,
  • Roman Pfeifer,
  • Jakob Hax,
  • Kai O. Jensen and
  • Hans-Christoph Pape

21 June 2021

Background: Fat embolism (FE) continues to be mentioned as a substantial complication following acute femur fractures. The aim of this systematic review was to test the hypotheses that the incidence of fat embolism syndrome (FES) has decreased since...

  • Review
  • Open Access
12 Citations
5,626 Views
12 Pages

Erectile Dysfunction in Men with Chronic Obstructive Pulmonary Disease

  • Lorenzo Marinelli,
  • Fabio Lanfranco,
  • Giovanna Motta and
  • Marco Zavattaro

21 June 2021

Erectile dysfunction (ED) seems to be a widespread sexual issue in men affected by chronic obstructive pulmonary disease (COPD). Multiple causes appear to be involved such as hormonal imbalance, smoking habit, chronic inflammation, endothelial dysfun...

  • Article
  • Open Access
18 Citations
6,796 Views
8 Pages

Evaluation of SARS-CoV-2 in the Vaginal Secretions of Women with COVID-19: A Prospective Study

  • Elad Barber,
  • Michal Kovo,
  • Sophia Leytes,
  • Ron Sagiv,
  • Eran Weiner,
  • Orna Schwartz,
  • Margarita Mashavi,
  • Keren Holtzman,
  • Jacob Bar and
  • Anat Engel
  • + 1 author

21 June 2021

Objective: We aimed to investigate the likelihood of vaginal colonization with Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in pregnant and non-pregnant women with Coronavrus Disease 2019 (COVID-19). Materials and Methods: Vaginal swa...

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J. Clin. Med. - ISSN 2077-0383