Table of Contents
Antioxidants, Volume 9, Issue 3 (March 2020) – 81 articles
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Cover Story (view full-size image) Ageing increases the risks of arterial stiffness mainly through the effects of oxidative stress. [...] Read more. Ageing increases the risks of arterial stiffness mainly through the effects of oxidative stress. These effects of ageing and oxidative stress on arterial stiffness can be moderated by exercise training. Fibroblast growth factor 21 (FGF21) and adiponectin increase expression of genes involved in antioxidant pathways and decrease oxidative stress. In healthy non-obese active and sedentary individuals, distributed equally in younger and older age groups, ageing was positively associated with oxidative stress and arterial stiffness. However, these relationships were independent of exercise training and the FGF21–adiponectin axis. Contrary to the findings from previous studies, these results suggest that habitual exercise may not be effective in attenuating oxidative stress and arterial stiffness in healthy non-obese individuals. View this paper.