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Antioxidants, Volume 13, Issue 12

December 2024 - 160 articles

Cover Story: Neuroinflammation is a common feature in age-related neurodegenerative diseases like Alzheimer's and Parkinson's. This review highlights the role of mitochondrial oxidative stress in driving this inflammation. Mitochondria-generated reactive oxygen species (ROS) are key players in inflammatory signaling pathways, including inflammasomes and the cGAS-STING pathway. This response can ultimately trigger immunogenic cell death, such as pyroptosis, necroptosis, and metal-ion-induced cell death. Understanding these mechanisms can help us identify new therapeutic targets to modulate the inflammatory response and potentially slow disease progression. View this paper
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Articles (160)

  • Article
  • Open Access
1 Citations
1,046 Views
17 Pages

A New Approach in PLS/TPS Compatibilization Using Garlic Oil: Effect on Morphological and Antioxidant Properties

  • Maria Cidália R. Castro,
  • Pedro Veiga Rodrigues,
  • Vasco Cruz and
  • Ana Vera Machado

23 December 2024

The packaging industry has made efforts to reduce food waste and improve the resilience of food systems worldwide. Active food packaging, which incorporates active agents, represents a dynamic area where industry and academia have developed new strat...

  • Article
  • Open Access
6 Citations
4,429 Views
18 Pages

From Spent Black and Green Tea to Potential Health Boosters: Optimization of Polyphenol Extraction and Assessment of Their Antioxidant and Antibacterial Activities

  • Ahlam Harfoush,
  • Aseel Swaidan,
  • Salma Khazaal,
  • Elie Salem Sokhn,
  • Nabil Grimi,
  • Espérance Debs,
  • Nicolas Louka and
  • Nada El Darra

23 December 2024

Tea, one of the most popular beverages worldwide, generates a substantial amount of spent leaves, often directly discarded although they may still contain valuable compounds. This study aims to optimize the extraction of polyphenols from spent black...

  • Article
  • Open Access
2,215 Views
17 Pages

Oxidative Stress, Inflammation and Altered Glucose Metabolism Contribute to the Retinal Phenotype in the Choroideremia Zebrafish

  • Cécile Méjécase,
  • Neelima Nair,
  • Hajrah Sarkar,
  • Pablo Soro-Barrio,
  • Maria Toms,
  • Sophia Halliday,
  • Katy Linkens,
  • Natalia Jaroszynska,
  • Constance Maurer and
  • Nicholas Owen
  • + 1 author

23 December 2024

Reactive oxygen species (ROS) within the retina play a key role in maintaining function and cell survival. However, excessive ROS can lead to oxidative stress, inducing dysregulation of metabolic and inflammatory pathways. The chmru848 zebrafish mode...

  • Article
  • Open Access
5 Citations
2,060 Views
16 Pages

A Preliminary Investigation of Thermally Stable Schiff Base Metal Complexes for Hyperthermia: Synthesis and Biological Evaluation

  • Vigneswari Sankara Narayanan,
  • Soven Dhawa,
  • Amritha Sukumaran,
  • Bharathi Hassan Ganesh,
  • Jeya Rajendran,
  • Kondapa Naidu Bobba and
  • Prasanna Ramani

23 December 2024

A novel Schiff base ligand (L), bearing N2O2 donor sites, was derived from the condensation of 5-chloromethylisophthaldehyde and phenylpropanolamine (PPA). Mononuclear Co(II), Cu(II), and Zn(II) complexes were synthesized and were characterized by FT...

  • Article
  • Open Access
3 Citations
1,603 Views
22 Pages

23 December 2024

Antimicrobial blue light (aBL) has become a promising non-invasive method that uses visible light, typically within the 405–470 nm wavelength range, to efficiently inactivate a wide variety of pathogens. However, the mechanism of antimicrobial...

  • Article
  • Open Access
5 Citations
2,360 Views
23 Pages

Neuroprotective Potential of Indole-Based Compounds: A Biochemical Study on Antioxidant Properties and Amyloid Disaggregation in Neuroblastoma Cells

  • Tania Ciaglia,
  • Maria Rosaria Miranda,
  • Simone Di Micco,
  • Mariapia Vietri,
  • Gerardina Smaldone,
  • Simona Musella,
  • Veronica Di Sarno,
  • Giulia Auriemma,
  • Carla Sardo and
  • Ornella Moltedo
  • + 7 authors

23 December 2024

Based on the established neuroprotective properties of indole-based compounds and their significant potential as multi-targeted therapeutic agents, a series of synthetic indole–phenolic compounds was evaluated as multifunctional neuroprotectors...

  • Review
  • Open Access
5 Citations
3,031 Views
19 Pages

23 December 2024

In regenerative medicine, mesenchymal stem cells (MSCs) have shown their importance and potential in tissue reconstruction and immune system modification. However, such cells’ potential is often diminished by factors such as oxidative stress, i...

  • Article
  • Open Access
3 Citations
1,584 Views
23 Pages

Bioactive and Biological Potential of Black Chokeberry Leaves Under the Influence of Pressurized Liquid Extraction and Microwave-Assisted Extraction

  • Maja Repajić,
  • Ivona Elez Garofulić,
  • Ena Cegledi,
  • Erika Dobroslavić,
  • Sandra Pedisić,
  • Ksenija Durgo,
  • Ana Huđek Turković,
  • Jasna Mrvčić,
  • Karla Hanousek Čiča and
  • Verica Dragović-Uzelac

23 December 2024

To determine the optimal conditions of pressurized liquid extraction (PLE) and microwave-assisted extraction (MAE) of polyphenols from black chokeberry leaves (BCL), temperature, time and sample-to-solvent ratio (SSR) were varied to obtain maximum po...

  • Article
  • Open Access
6 Citations
6,477 Views
22 Pages

Optimization of Phenolic Content Extraction and Effects of Drying Treatments on Physicochemical Characteristics and Antioxidant Properties of Edible Mushroom Pleurotus ostreatus (Jacq.) P. Kumm (Oyster Mushroom)

  • Marcelo Villalobos-Pezos,
  • Ociel Muñoz-Fariña,
  • Kong Shun Ah-Hen,
  • María Fernanda Garrido-Figueroa,
  • Olga García-Figueroa,
  • Alexandra González-Esparza,
  • Luisbel González-Pérez de Medina and
  • José Miguel Bastías-Montes

23 December 2024

Edible mushrooms have been part of the human diet for centuries. Traditionally, they have been used for culinary and medicinal purposes due to their chemical composition and nutritional value, including their high antioxidant activity attributed to k...

  • Article
  • Open Access
1 Citations
1,522 Views
19 Pages

Melatonin Enhances the Low-Calcium Stress Tolerance by Regulating Brassinosteroids and Auxin Signals in Wax Gourd

  • Jingjing Chang,
  • Xuemei Zhu,
  • Yixuan Lian,
  • Jing Li,
  • Xiao Chen,
  • Zhao Song,
  • Lei Chen,
  • Dasen Xie and
  • Baige Zhang

22 December 2024

In plants, calcium (Ca) serves as an essential nutrient and signaling molecule. Melatonin is a biologically active and multi-functional hormone that plays an important role in improving nutrient use efficiency. However, its involvement in plant respo...

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Antioxidants - ISSN 2076-3921