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Antioxidants, Volume 14, Issue 1

January 2025 - 119 articles

Cover Story: Hydroxyl radicals are the most reactive oxidants among reactive oxygen species and a major cause of oxidative damage to biomolecules in several subcellular components. The excessive production of hydroxyl radicals is linked to diseases such as cancer and neurodegenerative disorders. Rapid and reliable detection of hydroxyl radicals near DNA and within subcellular organelles is important. However, the high reactivity and short half-lives of hydroxyl radicals result in exceptionally low concentrations, which pose significant challenges to their detection. This review highlights advances in fluorescent probes for the detection of hydroxyl radicals in distinct subcellular regions with an emphasis on the probe design, applications, and limitations, and it outlines pathways to enhance future development. View this paper
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Articles (119)

  • Article
  • Open Access
1 Citations
6,077 Views
13 Pages

Intermittent Fasting Protects Against the Progression from Acute Kidney Injury to Chronic Kidney Disease

  • Yoonjoo Jang,
  • Young Suk Kim,
  • Seo Rin Kim,
  • Dong Won Lee,
  • Soo Bong Lee and
  • Il Young Kim

20 January 2025

Acute kidney injury (AKI) is a major but often underestimated risk factor for the development of chronic kidney disease (CKD). Exploring innovative approaches to prevent this progression is critical. Intermittent fasting (IF), recognized for its meta...

  • Article
  • Open Access
1 Citations
3,115 Views
17 Pages

20 January 2025

Andrographis paniculata is mainly used to treat skin inflammations, wounds, and infections. In this study, Andrographis Herba, the aerial part of the plant, was proven to increase the viability of UVB-damaged HaCat cells and reduce reactive oxygen sp...

  • Article
  • Open Access
4 Citations
1,873 Views
18 Pages

20 January 2025

Acute alcoholic liver injury (AALI) remains a significant global health concern, primarily driven by oxidative stress. This study investigated the protective mechanisms of Weizmannia coagulans BC99 against alcohol-induced oxidative stress using a dua...

  • Review
  • Open Access
2 Citations
2,195 Views
21 Pages

Molecular Insights in the Anticancer Activity of Natural Tocotrienols: Targeting Mitochondrial Metabolism and Cellular Redox Homeostasis

  • Raffaella Chiaramonte,
  • Giulia Sauro,
  • Domenica Giannandrea,
  • Patrizia Limonta and
  • Lavinia Casati

20 January 2025

The role of mitochondria as the electric engine of cells is well established. Over the past two decades, accumulating evidence has pointed out that, despite the presence of a highly active glycolytic pathway (Warburg effect), a functional and even up...

  • Article
  • Open Access
6 Citations
1,898 Views
30 Pages

The Role of Extracts of Edible Parts and Production Wastes of Globe Artichoke (Cynara cardunculus L. var. scolymus (L.)) in Counteracting Oxidative Stress

  • Valentina Laghezza Masci,
  • Irene Mezzani,
  • Enrica Alicandri,
  • William Tomassi,
  • Anna Rita Paolacci,
  • Stefano Covino,
  • Vittorio Vinciguerra,
  • Elisabetta Catalani,
  • Davide Cervia and
  • Mario Ciaffi
  • + 2 authors

20 January 2025

In addition to the immature edible flower heads, the cultivation of globe artichoke (Cynara cardunculus L. var. scolymus (L.) Fiori) generates substantial quantities of by-products, including leaves, stems, and roots, which constitute potential sourc...

  • Review
  • Open Access
6 Citations
2,234 Views
22 Pages

20 January 2025

Oxidative stress is a state of imbalance between the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and the antioxidant defence system in the body. Oxidative stress may be associated with a variety of diseases, such a...

  • Article
  • Open Access
2 Citations
1,899 Views
24 Pages

20 January 2025

To investigate the effect of tannic acid (TA) on the growth, disease resistance, and intestinal health of Chinese soft-shelled turtles, individual turtles were fed with 0 g/kg (CG), 0.5 g/kg, 1 g/kg, 2 g/kg, and 4 g/kg TA diets for 98 days. Afterward...

  • Article
  • Open Access
2 Citations
1,685 Views
20 Pages

20 January 2025

A water-soluble polysaccharide from foxtail millet (FM-D1) was isolated and purified through gradient ethanol precipitation and column chromatography. Size-Exclusion Chromatography–Multi-Angle Light Scattering–Refractive Index (SEC-MALLS-...

  • Article
  • Open Access
3 Citations
2,280 Views
17 Pages

20 January 2025

This study explores whether molecular hydrogen (H2) administration can alleviate cognitive and immunological disturbances in a mouse model of vascular dementia (VaD). Adult male C57BL/6 mice underwent bilateral common carotid artery stenosis to induc...

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Antioxidants - ISSN 2076-3921Creative Common CC BY license