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Brain Sciences, Volume 11, Issue 9

September 2021 - 141 articles

Cover Story: The COVID-19 lockdown determined important changes in the sleep of a large percentage of the world population. We assessed the modifications of reported sleep patterns and disturbances in Italian children and adolescents with autism spectrum disorders (ASD) or attention deficit hyperactivity disorders (ADHD), compared to control children, before and during the COVID-19 lockdown in Italy. Parents of 100 ASD, 236 ADHD patients, and 340 healthy children filled out an anonymous online survey and a modified version of the Sleep Disturbance Scale for Children (SDSC), advertised via social media, to evaluate sleep patterns and disturbances of their children before and during the lockdown. View this paper
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Articles (141)

  • Review
  • Open Access
26 Citations
7,031 Views
13 Pages

Developing a Digital Solution for Remote Assessment in Multiple Sclerosis: From Concept to Software as a Medical Device

  • Anneke van der Walt,
  • Helmut Butzkueven,
  • Robert K. Shin,
  • Luciana Midaglia,
  • Luca Capezzuto,
  • Michael Lindemann,
  • Geraint Davies,
  • Lesley M. Butler,
  • Cristina Costantino and
  • Xavier Montalban

21 September 2021

There is increasing interest in the development and deployment of digital solutions to improve patient care and facilitate monitoring in medical practice, e.g., by remote observation of disease symptoms in the patients’ home environment. Digital heal...

  • Article
  • Open Access
2 Citations
2,796 Views
17 Pages

21 September 2021

Recording ultrasonic vocalizations (USVs) is a highly sensitive tool to study the dam–pup social relationships, and USV recordings have been used to study the effects of ethanol on pups. Gestational effects of ethanol on the emission of USVs in rat p...

  • Article
  • Open Access
15 Citations
3,902 Views
24 Pages

Brain Abnormalities in Individuals with a Desire for a Healthy Limb Amputation: Somatosensory, Motoric or Both? A Task-Based fMRI Verdict

  • Martina Gandola,
  • Laura Zapparoli,
  • Gianluca Saetta,
  • Carlo Reverberi,
  • Gerardo Salvato,
  • Silvia Amaryllis Claudia Squarza,
  • Paola Invernizzi,
  • Maurizio Sberna,
  • Peter Brugger and
  • Gabriella Bottini
  • + 1 author

21 September 2021

Body integrity dysphoria (BID), a long-lasting desire for the amputation of physically healthy limbs, is associated with reduced fMRI resting-state functional connectivity of somatosensory cortices. Here, we used fMRI to evaluate whether these findin...

  • Article
  • Open Access
4 Citations
2,791 Views
17 Pages

21 September 2021

Binge alcohol consumption and alcohol use disorders (AUD) are prevalent, and there is comorbidity with depression and anxiety. Potential underlying mechanisms include neurophysiological, genetic, and metabolic changes resulting from alcohol exposure....

  • Systematic Review
  • Open Access
7 Citations
3,956 Views
29 Pages

Has the Phase of the Menstrual Cycle Been Considered in Studies Investigating Pressure Pain Sensitivity in Migraine and Tension-Type Headache: A Scoping Review

  • Francisca Curiel-Montero,
  • Francisco Alburquerque-Sendín,
  • César Fernández-de-las-Peñas and
  • Daiana P. Rodrigues-de-Souza

21 September 2021

Objective: The aim of this scoping review was to identify if the phase of the menstrual cycle was considered in observational studies comparing pressure pain sensitivity between women with migraine or tension-type headache (TTH) and headache-free wom...

  • Review
  • Open Access
5 Citations
4,121 Views
12 Pages

SUNCT/SUNA in Pediatric Age: A Review of Pathophysiology and Therapeutic Options

  • Carlo Alberto Cesaroni,
  • Jacopo Pruccoli,
  • Luca Bergonzini,
  • Giuseppe Quatrosi,
  • Luigi Vetri,
  • Michele Roccella and
  • Antonia Parmeggiani

21 September 2021

The International Classification of Headache Disorders, 3rd edition (ICHD3) defines Short-lasting Unilateral Neuralgiform Headache Attacks (SUNHA) as attacks of moderate or severe, strictly unilateral head pain lasting from seconds to minutes, occurr...

  • Article
  • Open Access
6 Citations
2,413 Views
12 Pages

Serum Activin A as Brain Injury Biomarker in the First Three Days of Life. A Prospective Case—Control Longitudinal Study in Human Premature Neonates

  • Dimitra Metallinou,
  • Grigorios Karampas,
  • Eleftheria Lazarou,
  • Nikoletta Iacovidou,
  • Panagiota Pervanidou,
  • Katerina Lykeridou,
  • George Mastorakos and
  • Demetrios Rizos

20 September 2021

Disruption of normal intrauterine brain development is a significant consequence of premature birth and may lead to serious complications, such as neonatal brain injury (NBI). This prospective case-control longitudinal study aimed at determining the...

  • Article
  • Open Access
18 Citations
4,476 Views
9 Pages

Assessment of Bulbar Function in Adult Patients with 5q-SMA Type 2 and 3 under Treatment with Nusinersen

  • Svenja Brakemeier,
  • Benjamin Stolte,
  • Andreas Thimm,
  • Kathrin Kizina,
  • Andreas Totzeck,
  • Juan Munoz-Rosales,
  • Christoph Kleinschnitz and
  • Tim Hagenacker

20 September 2021

The antisense oligonucleotide nusinersen has been shown to improve trunk and limb motor function in patients with spinal muscular atrophy (SMA). Bulbar dysfunction, which is regularly present in SMA, is not captured by standard motor scores, and vali...

  • Article
  • Open Access
18 Citations
3,558 Views
12 Pages

Peripheral Nerve Impairment in a Mouse Model of Alzheimer’s Disease

  • Alessio Torcinaro,
  • Valentina Ricci,
  • Georgios Strimpakos,
  • Francesca De Santa and
  • Silvia Middei

20 September 2021

Sarcopenia, a geriatric syndrome involving loss of muscle mass and strength, is often associated with the early phases of Alzheimer’s disease (AD). Pathological hallmarks of AD including amyloid β (Aβ) aggregates which can be found in peripheral tiss...

  • Review
  • Open Access
16 Citations
7,121 Views
23 Pages

20 September 2021

The memory literature has identified interference and inhibition as two major sources of forgetting. While interference is generally considered to be a passive cause of forgetting arising from exposure to additional information that impedes subsequen...

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Brain Sci. - ISSN 2076-3425