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Microorganisms, Volume 13, Issue 9

2025 September - 258 articles

Cover Story: Microbial contamination of indoor environments is a major factor in infectious disease transmission. This study presents a novel system combining vaporized free chlorine components (mainly HOCl), with high-efficiency particulate filtration. Field tests in occupied classrooms showed an 85.5% reduction in airborne microbes within 2.25 hours. Contact assays estimated significant inactivation of E. coli, P. aeruginosa, and S. aureus (59.0–99.7%) even at a distance of 8 meters. Computational fluid dynamics indicated uniform diffusion of HOCl at concentrations within safety thresholds. These findings show that the system enables non-contact, sustained microbial control and provide evidence of its value as an infection control technology in public health and healthcare. View this paper
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Articles (258)

  • Article
  • Open Access
1,542 Views
20 Pages

Population Dynamics of Plasmodium vivax in Mexico Determined by CSP, Pvs25, and SSU 18S rRNA S-Type Polymorphism Analyses

  • Lilia González-Cerón,
  • Delfino de Jesús Gómez-Pérez,
  • Frida Santillán-Valenzuela,
  • Marbella Ovilla-Muñoz,
  • Carmen Guzmán-Bracho,
  • Angélica Pech-May,
  • Gerardo R. Amores,
  • Alberto Montoya-Pérez and
  • Cuauhtémoc Villarreal-Treviño

In Mexico, Plasmodium vivax transmission has been confined to the northwestern and southern regions since 2000. Parasites from five malaria foci were analyzed using three genetic markers. The circumsporozoite gene was examined by PCR-RFLP and sequenc...

  • Article
  • Open Access
1,810 Views
19 Pages

The CRISPR-Cas9 System in Entamoeba histolytica Trophozoites: ehcp112 Gene Knockout and Effects on Other Genes in the V1 Virulence Locus

  • Luz Virginia Reyes,
  • Guillermina García-Rivera,
  • Rosario Javier-Reyna,
  • Edgar Morales-Rios,
  • Sergio Tinajero,
  • Cecilia Bañuelos,
  • Daniel Talamás-Lara and
  • Esther Orozco

Gene editing enables a better understanding of protein functions. The genome of the protozoan parasite Entamoeba histolytica contains a 4500 bp DNA fragment comprising the ehcp112, ehadh, and ehrabb genes, which together form the V1 virulence locus....

  • Article
  • Open Access
1 Citations
1,482 Views
18 Pages

Prevalence and Genetic Characteristics of Avian Chlamydia in Birds in Guangxi, Southwestern China

  • Jian-Ming Long,
  • Hai-Tao Zhong,
  • Ya-Yu Deng,
  • Jun-Wei Yang,
  • Mei-Chi Chen,
  • Yan-Jiao Liang,
  • Ke-Wei Chen,
  • Jing-Ting Yang,
  • Tian-Chao Wei and
  • Jian-Ni Huang
  • + 1 author

Avian chlamydiosis, primarily caused by Chlamydia psittaci (C. psittaci), poses significant threats to poultry and avian trade. Emerging species such as Chlamydia gallinacea (C. gallinacea), Chlamydia avium (C. avium), and Chlamydia ibidis (C. ibidis...

  • Article
  • Open Access
1,053 Views
15 Pages

The gut microbiota plays a pivotal role in host health. Dietary components such as waxy maize starch (WMS) and malate-debranched WMS (MADBS) may serve as modulators of microbial composition and function. In this study, the effects of WMS and MADBS on...

  • Review
  • Open Access
2 Citations
1,632 Views
32 Pages

Harnessing Microbial Power for a Sustainable Future Food System

  • Andreea Loredana Birgovan (Rhazzali),
  • Elena Simina Lakatos,
  • Lucian Ionel Cioca,
  • Natalia Lorela Paul,
  • Sorin Daniel Vatca,
  • Erzsebeth Kis and
  • Roxana Lavinia Pacurariu

Microorganisms are transforming the way we address sustainability across agriculture, food production, waste remediation, bioenergy, and industrial bioprocessing, offering novel solutions for the food systems of tomorrow. This systematic review exami...

  • Article
  • Open Access
2 Citations
909 Views
13 Pages

In Vitro Antimicrobial Activity of Contezolid Against Mycobacterium tuberculosis and Absence of Cross-Resistance with Linezolid

  • Li Wang,
  • Jianxia Chen,
  • Yifan He,
  • Ruijuan Zheng,
  • Jie Wang,
  • Xiaochen Huang,
  • Wei Sha and
  • Lianhua Qin

Tuberculosis (TB) persists as a formidable global health threat, especially with the rising incidence of multidrug-resistant strains. This study aimed to evaluate the in vitro activity of contezolid, a novel oxazolidinone antibiotic, against Mycobact...

  • Article
  • Open Access
2 Citations
1,014 Views
19 Pages

Nitrogen use efficiency (NUE) in rice cultivation is a key determinant of sustainable agriculture, yet the interaction between NUE and the dynamics of rhizosphere soil microbial communities remain poorly understood. In this study, the changes in rhiz...

  • Article
  • Open Access
1,498 Views
12 Pages

Development of a Chemiluminescence Immunoassay for the Serological Diagnosis of Sheep and Bovine Brucellosis

  • Xin Yan,
  • Mingze Chen,
  • Yuning Liu,
  • Mingjun Sun,
  • Mengkun Huang,
  • Jihui Jin,
  • Jiaqi Li,
  • Xiangxiang Sun,
  • Mengda Liu and
  • Wenlong Nan
  • + 4 authors

Brucellosis, a zoonotic infection caused by the intracellular pathogen Brucella, leads to chronic multi-organ damage. Currently, rapid, accurate, and sensitive diagnostic technologies are crucial for the prevention and control of brucellosis. This st...

  • Review
  • Open Access
4 Citations
4,210 Views
30 Pages

Preterm birth remains a significant global health challenge and is strongly associated with heightened risks of long-term neurodevelopmental impairments, including cognitive delays, behavioural disorders, and emotional dysregulation. In recent years,...

  • Article
  • Open Access
721 Views
21 Pages

Root rot diseases caused by Ganoderma pseudoferreum and Pyrrhoderma noxium inflict substantial economic losses in rubber tree (Hevea brasiliensis) cultivation, while conventional control methods face environmental and resistance challenges. This stud...

  • Article
  • Open Access
1 Citations
3,738 Views
18 Pages

When Precision Matters: Bone Marrow Cytology Meets qPCR in a Pilot Study Quantifying Leishmania infantum Load in Dogs

  • Juliana Costa,
  • Ana Rita Silva,
  • Filipe Sampaio,
  • Ana Patrícia Alves,
  • Hugo Silva,
  • Hugo Lima de Carvalho,
  • Carlos Sousa,
  • Manuel Simões,
  • Cátia Fernandes and
  • Ricardo Lopes
  • + 5 authors

Leishmania infantum is the causative agent of canine leishmaniosis (CanL), a zoonotic disease of considerable clinical and epidemiological concern. Quantification of parasite load is valuable for clinical management, particularly in low-parasite-load...

  • Article
  • Open Access
1 Citations
1,438 Views
17 Pages

MicroAIbiome: Decoding Cancer Types from Microbial Profiles Using Explainable Machine Learning

  • Md Motiur Rahman,
  • Shiva Shokouhmand,
  • Saeka Rahman,
  • Nafisa Nawar Tamzi,
  • Smriti Bhatt and
  • Miad Faezipour

Microbial communities within human tissues are increasingly recognized as promising biomarkers for cancer detection. However, leveraging microbiome data for multiclass cancer classification remains challenging due to its compositional structure, high...

  • Case Report
  • Open Access
870 Views
10 Pages

Diagnostic Challenges of Cyclosporiasis in Chronic Diarrhea: A Case Study

  • Estera Banasik,
  • Agnieszka Dobrowolska,
  • Lucyna Woźnicka-Leśkiewicz and
  • Piotr Eder

Cyclosporiasis, caused by Cyclospora cayetanensis, is a rare opportunistic infection, particularly in immunosuppressed patients with inflammatory bowel disease (IBD). Its clinical presentation may mimic IBD, with chronic diarrhea and anemia resistant...

  • Case Report
  • Open Access
993 Views
11 Pages

Periorbital and Central Nervous System Infection Due to Arcanobacterium haemolyticum: Case Report and Review of the Literature

  • Pierangelo Chinello,
  • Alessandro Capone,
  • Samir Al Moghazi,
  • Paolo Cirillo,
  • Carla Fontana and
  • Stefania Cicalini

Arcanobacterium haemolyticum is a facultative anaerobe, catalase-negative, Gram-positive pleomorphic rod, most commonly responsible for pharyngeal infections. Invasive A. haemolyticum infections are rare and typically involve immunocompromised patien...

  • Article
  • Open Access
1,034 Views
15 Pages

Skin health is significantly impacted by factors such as melanin production, UV-induced photodamage, and wound healing. Excessive melanin leads to hyperpigmentation, while UVA radiation accelerates skin aging and oxidative stress. This study investig...

  • Article
  • Open Access
888 Views
21 Pages

Although hydrocarbon-degrading bacteria utilize a wide range of alkanes, the global metabolic features and regulatory mechanisms governing their growth on alkanes with different chain lengths remain incompletely elucidated. In this study, we analyzed...

  • Article
  • Open Access
627 Views
14 Pages

Enhanced Natural Attenuation (ENA) can accelerate pollutant degradation by adding electron acceptors or nutrients. However, its impact on carbon-fixing microorganisms, which are widely found in the natural attenuation process, remains unclear. In thi...

  • Communication
  • Open Access
840 Views
10 Pages

Human herpesvirus 6 (HHV-6) establishes lifelong latency in immune cells and may contribute to the progression of ethanol-induced liver injury. To elucidate the contribution of HHV-6 to alcohol-induced hepatic injury, this study evaluated HHV-6 prote...

  • Article
  • Open Access
1 Citations
1,019 Views
12 Pages

Development of an RPA-CRISPR/LbaCas12a-Lateral Flow Assay for the Visual Detection of Chrysotila dentata (Haptophyta)

  • Jiating Yu,
  • Yun Shen,
  • Qinfei Zhang,
  • Xuxu Luo,
  • Yujie Zong,
  • Chengxu Zhou,
  • Hailong Huang and
  • Haibo Jiang

Chrysotila dentata (Haptophyta), a harmful algal bloom (HAB) species frequently occurring in coastal waters of China, is one with strong environmental adaptability that poses a serious threat to marine ecosystems and fisheries. Current molecular dete...

  • Article
  • Open Access
1,087 Views
28 Pages

Pathogen Identification, Antagonistic Microbe Screening, and Biocontrol Strategies for Aconitum carmichaelii Root Rot

  • Xingxun Dai,
  • Yuqin He,
  • Yu Su,
  • Huishu Mo,
  • Weichun Li,
  • Wanting Li,
  • Shuhui Zi,
  • Lufeng Liu and
  • Yining Di

The undefined microbial ecology of Aconitum carmichaelii root rot in western Yunnan constrains the advancement of eco-friendly control strategies. The identification of potential pathogenic determinants affecting A. carmichaelii growth is imperative...

  • Article
  • Open Access
1,363 Views
22 Pages

Although orthodontic appliances are widely used in daily practice, they also have their downsides due to the large amount of metal ions released from their surface. In this study, the influence of such released metal ions on the yeast Saccharomyces c...

  • Review
  • Open Access
3,346 Views
25 Pages

Neutralizing Antibodies vs. Viruses: Interacting Mechanisms and Escape Tactics

  • Hao Lu,
  • Yichen Liu,
  • Yue Song,
  • Longxin Chen,
  • Limeng Zhang,
  • Runting Li,
  • Xiaoning Nie,
  • Guoqiang Zhu,
  • Xueyan Ding and
  • Linqing Wang

Virus-neutralizing antibodies (VNAs) serve as critical components of host immune defense, countering viral infections by specifically recognizing epitopes on viral surface antigens to block viral entry and replication. This review elucidates the func...

  • Article
  • Open Access
2,681 Views
21 Pages

Probiotic Potential of Lactic Acid Bacteria Isolated from Moroccan Traditional Food Products

  • Ange Olivier Parfait Yao,
  • Majid Mounir,
  • Hary Razafindralambo and
  • Philippe Jacques

This study assessed the performance and potential use of lactic acid bacteria (LAB) from Moroccan traditional foods as probiotics in animal feed. Five LAB strains Lactiplantibacillus plantarum from whey sourdough, Leuconostoc pseudomesenteroides and...

  • Article
  • Open Access
1,376 Views
20 Pages

Role of NaCl and Glutamine on Biofilm Production from Pseudomonas aeruginosa

  • Laura Maria De Plano,
  • Antonella Iaconis,
  • Salvatore Papasergi,
  • Francesco Mediati,
  • Daniele Caruso,
  • Salvatore Pietro Paolo Guglielmino and
  • Domenico Franco

Pseudomonas aeruginosa is an opportunistic pathogen capable of forming antibiotic-resistant biofilms, contributing to persistent infections and treatment failure. Environmental factors such as osmolarity and nutrient availability are known to influen...

  • Article
  • Open Access
1,190 Views
15 Pages

Targeted Screening with the Use of Clinical Risk Factors for Detecting Congenital Cytomegalovirus Infection in Newborns: A Prospective Multicenter Cohort Study

  • Soromon Kataoka,
  • Masatoki Kaneko,
  • Li Yang,
  • Hajime Ota,
  • Moeka Seki,
  • Aya Kobamatsu,
  • Daiki Nakayama,
  • Yu Furuta,
  • Fumie Tanuma and
  • Hideto Yamada
  • + 3 authors

Congenital cytomegalovirus infection (cCMV) is one of the most common congenital infections. This study aimed to evaluate the diagnostic performance of targeted screening with the use of clinical risk factors for cCMV. A total of 3063 pregnant women...

  • Article
  • Open Access
1,652 Views
31 Pages

Metabarcoding Unveils Seasonal Soil Microbiota Shifts and Their Influence on Boletus edulis and Boletus reticulatus Mycelium in Quercus robur Stands

  • Serena Santolamazza-Carbone,
  • Laura Iglesias-Bernabé,
  • Elena Benito-Rueda,
  • Esther Barreal and
  • Pedro Pablo Gallego

Forest ecosystems undergo seasonal shifts in bacterial and fungal communities, but little is known about the specific microbiota associated with Quercus roburBoletus edulis systems. This study represents the first examination of seasonal chang...

  • Review
  • Open Access
1 Citations
2,501 Views
20 Pages

Over the past decade, significant attention has been directed toward understanding the role of the gut microbiome in health and disease. The gut microbiota, comprising a complex and diverse community of microorganisms, has been linked to numerous con...

  • Article
  • Open Access
716 Views
19 Pages

Unveiling Bacterial Diversity in Portuguese Red Wine Effluents Through a Metagenomic Approach

  • Ana Gabriela Gomes,
  • Ana Cláudia Sousa,
  • João S. Carreira,
  • Alberto Oliveira,
  • Marta C. Justino and
  • Carla Amarelo Santos

The sustainable reuse of agro-industrial effluents requires a detailed understanding of their microbial composition, especially in the context of integrated vineyard–winery ecosystems. This study investigated the bacterial communities present i...

  • Article
  • Open Access
650 Views
13 Pages

Acanthospermum australe Extract Inhibits the Chaperone Activity of Plasmodium falciparum Heat Shock Protein 70-1

  • Ntombikhona Appear Koza,
  • Ntokozo Nkosinathi Myeza,
  • Heinrich Hoppe,
  • Rebamang Anthony Mosa,
  • Abidemi Paul Kappo,
  • Mthokozisi Blessing Cedric Simelane and
  • Andrew Rowland Opoku

The resistance of malaria parasites towards the current antimalarial therapies continues to fuel the search for new antimalarial drugs, preferably from natural sources. This study aimed to investigate the potential of the dichloromethane extract of A...

  • Review
  • Open Access
3 Citations
3,518 Views
16 Pages

Antimicrobial resistance has emerged as one of the most critical public health challenges of the 21st century, threatening to undermine the foundations of modern medicine. In 2019, bacterial infections accounted for 13.6% of all global deaths, with m...

  • Article
  • Open Access
1 Citations
1,297 Views
14 Pages

Detection of Aeromonas hydrophila by Basic and Fluorescent MIRA Assays

  • Qiuya Huang,
  • Fa Dai,
  • Lujia Su,
  • Miaomiao Zhang,
  • Xinjie Miao,
  • Yujie Ding,
  • Cheng Xu and
  • Jiehao Xu

Aeromonas hydrophila is a prevalent opportunistic pathogen in aquaculture. To establish a rapid, convenient, and accurate detection method for A. hydrophila, this study developed and evaluated Multi-Enzyme Isothermal Rapid Amplification (MIRA) assays...

  • Systematic Review
  • Open Access
1 Citations
1,811 Views
30 Pages

Role of Lipidomics in Respiratory Tract Infections: A Systematic Review of Emerging Evidence

  • Vasiliki E. Georgakopoulou,
  • Konstantinos Dodos and
  • Vassiliki C. Pitiriga

Lower respiratory tract infections (LRTIs) remain a major cause of global morbidity and mortality, yet accurate pathogen identification and risk stratification continue to pose clinical challenges. Lipidomics—the comprehensive analysis of lipid...

  • Article
  • Open Access
1,144 Views
25 Pages

Posttranscriptional 3′-Terminal Modifications of Escherichia coli RNA Fragments Evolved for Diversity Boosting

  • Nikita M. Kamoldinov,
  • Valery V. Panyukov,
  • Nikolay P. Kolzhetsov,
  • Natalia Y. Markelova,
  • Konstantin S. Shavkunov,
  • Uliana S. Shvyreva,
  • Olga V. Alikina,
  • Olga A. Glazunova,
  • Iuliia A. Praslova and
  • Olga N. Ozoline

An emerging area of microbial biology focuses on oligonucleotides excised from functional RNAs and subsequently fulfilling an independent cellular role. Some of these products are subjected to modifications that may expand their functional inventory....

  • Article
  • Open Access
902 Views
23 Pages

Dictyophora rubrovalvata is a soil-cultivated edible fungus with high economic and medicinal value, yet its continuous cultivation is frequently hindered by cropping obstacles. To elucidate the underlying ecological mechanisms, this study employed me...

  • Article
  • Open Access
1,120 Views
13 Pages

First Detection of Cytauxzoon spp. DNA in Questing Ixodes ricinus Ticks

  • Marina L. Meli,
  • Theres Meili,
  • Benita Pineroli,
  • Eva Boenzli,
  • Ramon M. Eichenberger,
  • Barbara Willi and
  • Regina Hofmann-Lehmann

Feline cytauxzoonosis is an emerging tick-borne disease in Europe. While infections have been reported in different European countries, the tick vector remains unknown. This study investigated 665 ticks collected in 2019 (n = 160), 2022 (n = 7), and...

  • Article
  • Open Access
996 Views
11 Pages

Prevalence and Clinical Characteristics of Visceral Involvement in HIV-Associated Kaposi Sarcoma: A Three-Year Retrospective Cohort Study at a Tertiary Care Center in Mexico

  • Emily Itzel Pecero-García,
  • Juan Carlos Domínguez-Hermosillo,
  • Yessica Sara Pérez-González,
  • Juan Pablo Sánchez-Navarro,
  • Mauricio Alfredo Ambriz-Alarcón,
  • Natalia Jaime-Gómez,
  • Sol Ramírez-Ochoa,
  • Gabino Cervantes-Guevara,
  • Berenice Vicente-Hernández and
  • Enrique Cervantes-Pérez
  • + 1 author

Despite advances in the understanding of Kaposi sarcoma (KS), research from resource-limited settings remains limited. This study aimed to estimate the proportion of epidemic visceral KS among Mexican people living with HIV (PLHIV) and to describe th...

  • Article
  • Open Access
2 Citations
4,144 Views
11 Pages

Cutibacterium acnes Phylotyping and Antibiotic Resistance to Six Antibiotics: A Bulgarian Study

  • Lyudmila Boyanova,
  • Georgi Dimitrov,
  • Vessela Raykova,
  • Kircho Patrikov,
  • Raina Gergova and
  • Rumyana Markovska

Cutibacterium acnes subspecies/phylotypes can cause infections requiring antibiotic therapy. Phylotyping of 73 (55 acneic and 18 non-acneic) C. acnes strains was performed, and antibiotic susceptibility was tested by E tests, breakpoint susceptibilit...

  • Article
  • Open Access
668 Views
15 Pages

Transmissibility of Clade IIb Monkeypox Virus in Young Rabbits

  • Zhaoliang Chen,
  • Lei Zhang,
  • Linzhi Li,
  • Mingjie Shao,
  • Mingda Zhang,
  • Zongzheng Zhao,
  • Chao Shang,
  • Zirui Liu,
  • Juxiang Liu and
  • Zhendong Guo

The monkeypox virus (MPXV) has spread globally, posing a severe challenge to global public health. This study systematically evaluated the aerosol shedding dynamics of the epidemic Clade IIb MPXV strain in infected young rabbits, along with its direc...

  • Article
  • Open Access
1,046 Views
22 Pages

PCV2 Infection Represses the Differentiation of Light Zone Germinal Center B Cells by Inhibiting Their Interaction with Helper Cells

  • Tengfei Shi,
  • Qian Du,
  • Jiasai Kang,
  • Haoshu Zhang,
  • Xinru Xu,
  • Yang Wang,
  • Dewen Tong and
  • Yong Huang

Porcine circovirus 2 (PCV2) is one of the most widespread immunosuppressive viruses, impairing the protective efficacy of vaccines in pig herds. Previous studies have shown that PCV2 infection reduces the generation of immune memory and antibody secr...

  • Review
  • Open Access
2 Citations
2,078 Views
19 Pages

Virulence Regulation in Borrelia burgdorferi

  • Sierra George and
  • Zhiming Ouyang

Borrelia burgdorferi, the causative agent of Lyme disease, is the most common vector-borne disease in the United States. Compared with other bacterial pathogens, B. burgdorferi has many unique features. For instance, its highly segmented genome was p...

  • Article
  • Open Access
767 Views
18 Pages

Sorption–Biological Treatment of Coastal Substrates of the Barents Sea in Low Temperature Using the Rhodococcus erythropolis Strain HO-KS22

  • Vladimir Myazin,
  • Maria Korneykova,
  • Nadezhda Fokina,
  • Ekaterina Semenova,
  • Tamara Babich and
  • Milana Murzaeva

The efficiency of the sorption–biological method for treatment of oil-polluted coastal substrates (soil and sand) of the Barents Sea under low temperature (10 °C) using the active hydrocarbon-oxidizing bacterial strain Rhodococcus erythropo...

  • Article
  • Open Access
1,066 Views
20 Pages

Unveiling Species Diversity of Plectosphaerellaceae (Sordariomycetes) Fungi Involved in Rhizome and Root Rots of Ginger in Shandong Province, China

  • Qian Zhao,
  • Ao Jia,
  • Hongjuan Yang,
  • Jinming Hu,
  • Xuli Gao,
  • Weiqin Zhao,
  • Lifeng Zhou,
  • Miao Zhang,
  • Zhaoxia Li and
  • Weihua Zhang

Ginger holds significant economic importance in both China and worldwide agriculture. Fungi from the family Plectosphaerellaceae are globally recognized as aggressive plant pathogens. However, the effects of Plectosphaerellaceae species on ginger hav...

  • Article
  • Open Access
1,008 Views
22 Pages

Amino Acid Balanced Compound Low-Protein Diets Improve Resource Efficiency in Sanhua Goose Production: Impacts on Metabolism, Gut Health, and Microbial Diversity

  • Xianze Wang,
  • Huiying Wang,
  • Yi Liu,
  • Guangquan Li,
  • Daqian He,
  • Shufang Chen,
  • Huiyan Jia,
  • Jiuli Dai and
  • Xiao Zhou

This study investigated a compound low-protein diet (CLPD) strategy to reduce soybean meal (SBM) dependency in meat geese. Diets were formulated with crude protein (CP) levels decreasing from 16.5% (corn-soybean meal diet, CSD) to 9.8%, incorporating...

  • Article
  • Open Access
1 Citations
1,063 Views
18 Pages

The transition between anaerobic and aerobic conditions represents a fundamental ecological process occurring ubiquitously in both natural ecosystems and engineered wastewater treatment systems. This study investigated the microbial community success...

  • Article
  • Open Access
642 Views
20 Pages

This study conducted a transcriptome sequencing analysis of the interaction between Chenopodium album and Botrytis strain HZ-011 to identify genes involved in the response to fungal infections and elucidate the molecular mechanisms underlying the int...

  • Review
  • Open Access
2 Citations
2,385 Views
34 Pages

Pattern Recognition Receptors (PRRs) Expression and Activation in COVID-19 and Long COVID: From SARS-CoV-2 Escape Mechanisms to Emerging PRR-Targeted Immunotherapies

  • Luca Maddaloni,
  • Ginevra Bugani,
  • Matteo Fracella,
  • Camilla Bitossi,
  • Alessandra D’Auria,
  • Francesca Aloisi,
  • Abir Azri,
  • Letizia Santinelli,
  • Manel Ben M’Hadheb and
  • Carolina Scagnolari
  • + 2 authors

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is recognized by pattern recognition receptors (PRRs), which play a vital role in triggering innate immune responses such as the production of type I and III interferons (IFNs). While modes...

  • Article
  • Open Access
1,012 Views
21 Pages

Therapeutic Potential of Probiotic-Derived P8 Protein as an Anti-Metastatic Agent in Colorectal Cancer

  • Byung Chull An,
  • Seungwoo Kim,
  • Jaewon Ha,
  • Sang-Hyuk Seok,
  • Jun Won Park,
  • Yongku Ryu and
  • Myung Jun Chung

We previously described the use of probiotics to deliver a Lactobacillus rhamnosus-derived therapeutic protein, P8, which has been identified as a candidate colorectal cancer (CRC) suppressor protein with anti-proliferation and anti-migration activit...

  • Article
  • Open Access
1 Citations
1,869 Views
16 Pages

Antibiotic-loaded bone cements (ALBCs) are used to prevent and treat periprosthetic joint infections (PJI). This study compares the in vitro release and antibacterial effectiveness of gentamicin from Palacos® R+G and tobramycin from Simplex®...

  • Article
  • Open Access
1,136 Views
9 Pages

Real-Time PCR Test (Flora Select™) for Assessing the Effectiveness of Bacterial Vaginosis Treatment During Pregnancy

  • Hajime Ota,
  • Shigeki Shimada,
  • Yuta Kobayashi,
  • Tatsuya Yoshiwara,
  • Osamu Yoshino,
  • Yoshiyuki Fukushi,
  • Shinichiro Wada,
  • Soromon Kataoka and
  • Hideto Yamada

Preterm birth is a major cause of perinatal mortality and morbidity in newborns, and its risk is increased by bacterial vaginosis (BV) during pregnancy. This multicenter prospective cohort study aimed to evaluate whether Flora select™ (FS), a n...

  • Article
  • Open Access
1 Citations
849 Views
24 Pages

Karst rivers are increasingly contaminated by both heavy metals and nanoplastics, yet their combined impact on riparian litter decomposition remains unresolved. We conducted a 90-day microcosm experiment using Miscanthus floridulus leaf litter collec...

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Microorganisms - ISSN 2076-2607