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Microorganisms, Volume 13, Issue 8

August 2025 - 252 articles

Cover Story: Cardiac surgery, particularly procedures involving cardiopulmonary bypass (CPB), is associated with a high risk of postoperative complications, including systemic inflammatory response syndrome (SIRS), postoperative atrial fibrillation (POAF), and infection. Growing evidence suggests that the gut–heart axis, through mechanisms involving intestinal barrier integrity and gut microbiota homeostasis, may influence these outcomes. This review summarizes the relationship between gut microbiota composition and the inflammatory response in patients undergoing cardiac surgery and the extent to which these alterations impact clinical outcomes. The reviewed studies consistently show that cardiac surgery induces notable alterations in microbial diversity and composition during the perioperative period. View this paper
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Articles (252)

  • Article
  • Open Access
684 Views
16 Pages

Insights into the Genomic Architecture and Improvement of the Capabilities of Acinetobacter calcoaceticus for the Biodegradation of Petroleum Hydrocarbons

  • Yaning Zeng,
  • Mutian Wang,
  • Xiaoyu Chang,
  • Leilei Wang,
  • Xiaowen Fu,
  • Yujie Huang,
  • Fanyong Song,
  • Lei Ji and
  • Jianing Wang

Petroleum-contaminated terrestrial ecosystems require effective bioremediation strategies. In this study, genomic analysis revealed key biodegradation genes on the Acinetobacter calcoaceticus 21# chromosome: alkane hydroxylases (alkB, almA, LadA) and...

  • Article
  • Open Access
564 Views
14 Pages

vapD Mutation Shows Impairment in the Persistence of Helicobacter pylori Within AGS Cells

  • Rosario Morales-Espinosa,
  • Gabriela Delgado,
  • Carlos A. Santiago,
  • Alejandro Flores-Alanis,
  • Rafael Diaz-Mendez,
  • Alberto Gonzalez-Pedraza,
  • José L. Méndez and
  • Alejandro Cravioto

The Helicobacter pylori vapD gene is transcribed and expressed when the bacteria are within the gastric cell. In this current study, we investigated how vapD knockout affects the survival of H. pylori inside human gastric adenocarcinoma cells. We con...

  • Article
  • Open Access
599 Views
15 Pages

Caenorhabditis elegans, a free-living nematode model, secretes neuropeptides, but the ecological roles of its peptide exudates in regulating rhizosphere microbial activity remain largely unexplored. We identified six short peptides (P1, P9, P19, P20,...

  • Article
  • Open Access
1 Citations
1,088 Views
16 Pages

BCL-2 Multi-Strain Probiotics for Immunomodulation In Vitro and In Vivo Alleviation of Atopic Dermatitis

  • MinKyung Sung,
  • Seongrok Sim,
  • Ahyoung Lim,
  • Jin Seok Moon,
  • JongIk Jeon,
  • Keon Heo,
  • Woongkwon Kwak,
  • Myeong Soo Park,
  • Jungki Kwak and
  • EunYoung Park
  • + 1 author

Atopic dermatitis (AD) is a chronic inflammatory disorder with immune imbalance, including elevated IgE levels and mast cell activation mediated by Th2 cytokines, leading to allergic inflammation and impaired skin barrier function. Current treatment...

  • Article
  • Open Access
851 Views
21 Pages

Diet Quality Modulates Gut Microbiota Structure in Blastocystis-Colonised Individuals from Two Distinct Cohorts with Contrasting Sociodemographic Profiles

  • Claudia Muñoz-Yáñez,
  • Alejandra Méndez-Hernández,
  • Faviel Francisco González-Galarza,
  • Adria Imelda Prieto-Hinojosa and
  • Janeth Oliva Guangorena-Gómez

Diet and gut microbiota are significant determinants of host health, but how dietary quality modulates gut microbiota in Blastocystis-colonised individuals remains underexplored. We studied two contrasting cohorts: university students (FACSA, n = 46)...

  • Article
  • Open Access
1 Citations
711 Views
15 Pages

Broad Host Range Peptide Nucleic Acids Prevent Gram-Negative Biofilms Implicated in Catheter-Associated Urinary Tract Infections

  • Hannah Q. Karp,
  • Elizabeth S. Nowak,
  • Gillian A. Kropp,
  • Nihan A. Col,
  • Michael D. Schulz,
  • Nammalwar Sriranganathan and
  • Jayasimha Rao

Biofilms develop in sequential steps resulting in the formation of three-dimensional communities of microorganisms that are encased in self-produced extracellular polymeric substances. Biofilms play a key role in device-associated infections, such as...

  • Article
  • Open Access
971 Views
17 Pages

Macrolide-Resistant Bordetella pertussis in Hong Kong: Evidence for Post-COVID-19 Emergence of ptxP3-Lineage MT28 Clone from a Hospital-Based Surveillance Study

  • Tsz-Yung Hui,
  • Hayes Kam-Hei Luk,
  • Garnet Kwan-Yue Choi,
  • Sandy Ka-Yee Chau,
  • Lok-Man Tsang,
  • Cindy Wing-Sze Tse,
  • Ka-Kin Fung,
  • Jimmy Yiu-Wing Lam,
  • Ho-Leung Ng and
  • Tommy Hing-Cheung Tang
  • + 5 authors

A post-COVID surge of Bordetella pertussis was observed globally. China has reported a high level of macrolide-resistant Bordetella pertussis (MRBP) in recent years; however, the epidemiology of MRBP in Hong Kong remains unknown. We retrieved archive...

  • Article
  • Open Access
827 Views
26 Pages

Uropathogenic Escherichia coli in a Diabetic Dog with Recurrent UTIs: Genomic Insights and the Impact of Glucose and Antibiotics on Biofilm Formation

  • Inês C. Rodrigues,
  • Marisa Ribeiro-Almeida,
  • Joana Campos,
  • Leonor Silveira,
  • Liliana Leite-Martins,
  • Jorge Ribeiro,
  • Paula Martins da Costa,
  • Joana C. Prata,
  • Ângela Pista and
  • Paulo Martins da Costa

Recurrent urinary tract infections (UTIs) pose a significant clinical challenge in both human and veterinary medicine, due to antibiotic-resistant and biofilm-forming bacteria. We hypothesized that high glucose levels in diabetic animals enhance biof...

  • Article
  • Open Access
551 Views
22 Pages

The Sanniang Bay (SNB) and Dafeng River Estuary (DFR) in the Northern Beibu Gulf, China, are critical habitats for the Indo-Pacific humpback dolphin (Sousa chinensis). However, whether and how the decreased dissolved oxygen (DO) has happened in botto...

  • Article
  • Open Access
570 Views
17 Pages

Isolation and Characterization of the Trimethylamine (TMA)-Degrading Microbacterium lacticum Strain PM-1

  • Pai Feng,
  • Lei Zhang,
  • Yihao Wu,
  • Yuxuan Hu,
  • Wenda Chen,
  • Yuan Liu and
  • Jiayuan Yang

Trimethylamine (TMA) is a common malodorous pollutant known for its detrimental effects on both the natural environment and human health. In this study, strain PM-1 was successfully isolated from activated sludge in a sewage treatment plant and ident...

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Microorganisms - ISSN 2076-2607Creative Common CC BY license