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Pathogens, Volume 9, Issue 2

2020 February - 83 articles

Cover Story: This paper presents the results of a molecular surveillance study monitoring amdoparvoviruses and protoparvoviruses circulating in mustelids of insular British Columbia, Canada. By combining molecular epidemiology, genomic sequencing, phylogenetic analyses, and the study of host ecology, it was possible to clarify virus–host interaction dynamics and cross-species transmission patterns. We determined how hosts enable pathogen persistence and identified which hosts, among epidemiologically connected and susceptible populations, are crucial for this persistence and which are dead-end spillover hosts. In this multi-host system, viral and host factors affect viral persistence and distribution, shaping parvoviral ecology and evolution, with implications for insular carnivore conservation. View this paper
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Articles (83)

  • Review
  • Open Access
64 Citations
7,648 Views
22 Pages

Evaluation of Disease Causality of Rare Ixodes ricinus-Borne Infections in Europe

  • Tal Azagi,
  • Dieuwertje Hoornstra,
  • Kristin Kremer,
  • Joppe W. R. Hovius and
  • Hein Sprong

24 February 2020

In Europe, Ixodes ricinus ticks transmit pathogens such as Borrelia burgdorferi sensu lato and tick-borne encephalitis virus (TBEV). In addition, there is evidence for transmission to humans from I. ricinus of Anaplasma phagocytophilum, Babesia diver...

(This article belongs to the Collection Advances in Tick Research)
  • Case Report
  • Open Access
28 Citations
5,452 Views
6 Pages

First Case of Typhoid Fever due to Extensively Drug-resistant Salmonella enterica serovar Typhi in Italy

  • Michela Procaccianti,
  • Alice Motta,
  • Stefano Giordani,
  • Sara Riscassi and ,
  • Battista Guidi,
  • Monica Ruffini,
  • Valentina Maffini,
  • Susanna Esposito and
  • Icilio Dodi
  • + 4 authors+ 0 author

24 February 2020

Typhoid fever is a potentially severe and occasionally life-threatening bacteraemic illness caused by Salmonella enterica serovar Typhi (S. Typhi). In Pakistan, an outbreak of extensively drug-resistant (XDR) S. Typhi cases began in November 2016. We...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
21 Citations
5,187 Views
12 Pages

Simultaneous Immunization with Omp25 and L7/L12 Provides Protection against Brucellosis in Mice

  • Sonal Gupta,
  • Surender Mohan,
  • Vikas Kumar Somani,
  • Somya Aggarwal and
  • Rakesh Bhatnagar

24 February 2020

Currently used Brucella vaccines, Brucella abortus strain 19 and RB51, comprises of live attenuated Brucella strains and prevent infection in animals. However, these vaccines pose potential risks to recipient animals such as attenuation reversal and...

(This article belongs to the Special Issue Host Immune Responses and Pathogenesis to Brucella spp. Infection)
  • Article
  • Open Access
33 Citations
6,894 Views
15 Pages

Phenotypic and Molecular Detection of Biofilm Formation in Staphylococcus aureus Isolated from Different Sources in Algeria

  • Rachid Achek,
  • Helmut Hotzel,
  • Ibrahim Nabi,
  • Souad Kechida and ,
  • Djamila Mami,
  • Nassima Didouh,
  • Herbert Tomaso,
  • Heinrich Neubauer,
  • Ralf Ehricht and
  • Hosny El-Adawy
  • + 6 authors+ 1 author

24 February 2020

Staphylococcus aureus is an opportunistic bacterium causing a wide variety of diseases. Biofilm formation of Staphylococcus aureus is of primary public and animal health concern. The purposes of the present study were to investigate the ability of St...

(This article belongs to the Section Animal Pathogens)
  • Review
  • Open Access
121 Citations
17,639 Views
10 Pages

Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development

  • Balamurugan Shanmugaraj,
  • Ashwini Malla and
  • Waranyoo Phoolcharoen

22 February 2020

Novel Coronavirus (2019-nCoV) is an emerging pathogen that was first identified in Wuhan, China in late December 2019. This virus is responsible for the ongoing outbreak that causes severe respiratory illness and pneumonia-like infection in humans. D...

(This article belongs to the Section Vaccines and Therapeutic Developments)
  • Article
  • Open Access
31 Citations
6,611 Views
9 Pages

22 February 2020

Methylobacterium spp. are emerging opportunistic premise plumbing pathogens. Human infections linked to premise plumbing provide evidence of their routes of infection. Cells of a collection of representative strains of different Methylobacterium spec...

  • Article
  • Open Access
18 Citations
7,032 Views
16 Pages

Isolation of Acanthamoeba T5 from Water: Characterization of Its Pathogenic Potential, Including the Production of Extracellular Vesicles

  • Lissette Retana Moreira,
  • Daniel Vargas Ramírez,
  • Fátima Linares,
  • Alexa Prescilla Ledezma and ,
  • Annette Vaglio Garro,
  • Antonio Osuna,
  • Jacob Lorenzo Morales and
  • Elizabeth Abrahams Sandí
  • + 3 authors+ 0 author

21 February 2020

Acanthamoeba is a genus of free-living amoebae widely distributed in nature, associated with the development of encephalitis and keratitis. Despite the fact that it is common to find genotype T5 in environmental samples, only a few cases have been as...

(This article belongs to the Special Issue Selected Papers from the International Meeting on the Biology and Pathogenicity of Free-Living Amoebae (FLAM2019))
  • Article
  • Open Access
13 Citations
5,377 Views
18 Pages

Comparative Transcriptome Analysis of Two Cucumber Cultivars with Different Sensitivity to Cucumber Mosaic Virus Infection

  • Zdeno Šubr,
  • Lukáš Predajňa,
  • Katarína Šoltys,
  • Boris Bokor and ,
  • Jaroslav Budiš and
  • Miroslav Glasa
  • + 1 author+ 0 author

21 February 2020

Cucumber mosaic virus (CMV), with extremely broad host range including both monocots and dicots around the world, belongs to most important viral crop threats. Either natural or genetically constructed sources of resistance are being intensively inve...

(This article belongs to the Special Issue Genomics, Molecular, Genetics, and Diversity of Plant Disease Resistance)
  • Review
  • Open Access
32 Citations
7,194 Views
12 Pages

The Old and the New on Viral Diseases in Sturgeon

  • Davide Mugetti,
  • Paolo Pastorino,
  • Vasco Menconi,
  • Claudio Pedron and
  • Marino Prearo

21 February 2020

Although sturgeon production by aquaculture has increased worldwide, a major factor limiting its expansion are infectious diseases, although few data about viral diseases are available however. This review provides a rapid overview of viral agents de...

(This article belongs to the Special Issue Viral Diseases of Fish)
  • Article
  • Open Access
14 Citations
4,996 Views
20 Pages

Recognition of Lipoproteins by Toll-like Receptor 2 and DNA by the AIM2 Inflammasome Is Responsible for Production of Interleukin-1β by Virulent Suilysin-Negative Streptococcus suis Serotype 2

  • Agustina Lavagna,
  • Jean-Philippe Auger,
  • Stephen E. Giradin,
  • Nicolas Gisch and ,
  • Mariela Segura and
  • Marcelo Gottschalk
  • + 1 author+ 0 author

21 February 2020

Streptococcus suis serotype 2 is an important porcine bacterial pathogen and zoonotic agent causing sudden death, septic shock and meningitis. These pathologies are the consequence of an exacerbated inflammatory response composed of various mediators...

(This article belongs to the Special Issue Update on Streptococcus suis Research and Prevention in the Era of Antibiotic Restriction - 4th International Workshop on Streptococcus suis)
  • Article
  • Open Access
8 Citations
3,808 Views
17 Pages

20 February 2020

Staphylococcus aureus (S. aureus) is a commensal bacterium in the human body; however, the bacterium frequently generates serious inflammation and infectious diseases. Some strains of S. aureus, such as methicillin-resistant Staphylococcus aureus (MR...

  • Review
  • Open Access
32 Citations
8,947 Views
12 Pages

20 February 2020

Fc gamma receptors (FcγRs) are widely expressed on a variety of immune cells and play a myriad of regulatory roles in the immune system because of their structural diversity. Apart from their indispensable role in specific binding to the Fc por...

(This article belongs to the Section Immunological Responses and Immune Defense Mechanisms)
  • Article
  • Open Access
18 Citations
9,844 Views
11 Pages

Automated Diagnosis of Canine Gastrointestinal Parasites Using Image Analysis

  • Sandra Valéria Inácio,
  • Jancarlo Ferreira Gomes,
  • Alexandre Xavier Falcão,
  • Celso Tetsuo Nagase Suzuki and ,
  • Walter Bertequini Nagata,
  • Saulo Hudson Nery Loiola,
  • Bianca Martins dos Santos,
  • Felipe Augusto Soares,
  • Stefani Laryssa Rosa and
  • Katia Denise Saraiva Bresciani
  • + 7 authors+ 2 authors

20 February 2020

Because canine intestinal parasites are considered cosmopolitan, they carry significant zoonotic potential to public health. These etiological agents are routinely diagnosed using microscopic examination commonly used because of its low cost, simple...

(This article belongs to the Special Issue Animal Parasitic Diseases)
  • Article
  • Open Access
46 Citations
5,591 Views
16 Pages

CgSCD1 Is Essential for Melanin Biosynthesis and Pathogenicity of Colletotrichum gloeosporioides

  • Tan Wang,
  • Dandan Ren,
  • Han Guo,
  • Xue Chen and ,
  • Pinkuan Zhu,
  • Haozhen Nie and
  • Ling Xu
  • + 2 authors+ 0 author

20 February 2020

Colletotrichum gloeosporioides, an important phytopathogenic fungus, mainly infects tropical fruits and results in serious anthracnose. Previous studies have shown that melanin biosynthesis inhibitor can inhibit the melanization of the appressoria of...

(This article belongs to the Special Issue Colletotrichum spp. on Fruit Crops – State of the Art, Perspectives and Drawbacks)
  • Article
  • Open Access
18 Citations
6,655 Views
11 Pages

Detection of β-Lactamase-Producing Enterococcus faecalis and Vancomycin-Resistant Enterococcus faecium Isolates in Human Invasive Infections in the Public Hospital of Tandil, Argentina

  • Celia M. Schell,
  • Ana P. Tedim,
  • Mercedes Rodríguez-Baños,
  • Mónica D. Sparo and ,
  • Sabina Lissarrague,
  • Juan A. Basualdo and
  • Teresa M. Coque
  • + 2 authors+ 0 author

20 February 2020

The study’s aim was to analyze the population structure of enterococci causing human invasive infections in a medium-sized Argentinian Hospital coincidental with a 5 year-period of increased recovery of antibiotic resistant enterococci (2010&nd...

(This article belongs to the Special Issue Transmission of Antibiotic Resistant Bacteria and Genes: Unveiling the Jigsaw Pieces of a One Health Problem)
  • Article
  • Open Access
18 Citations
5,252 Views
16 Pages

Dissemination of Piscine orthoreovirus-1 (PRV-1) in Atlantic Salmon (Salmo salar) during the Early and Regenerating Phases of Infection

  • Kannimuthu Dhamotharan,
  • Håvard Bjørgen,
  • Muhammad Salman Malik,
  • Ingvild B. Nyman and ,
  • Turhan Markussen,
  • Maria K. Dahle,
  • Erling Olaf Koppang,
  • Øystein Wessel and
  • Espen Rimstad
  • + 4 authors+ 0 author

20 February 2020

Piscine orthoreovirus-1 (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar), but the line of events from infection, pathologic change, and regeneration has not been thoroughly described. In this stu...

(This article belongs to the Special Issue Heart and Skeletal Muscle Inflammation (HSMI) and Other Effects of Piscine orthoreovirus (PRV) Infections in Salmonids)
  • Review
  • Open Access
24 Citations
8,494 Views
30 Pages

Engineering of Live Chimeric Vaccines against Human Metapneumovirus

  • Daniela Ogonczyk Makowska,
  • Marie-Ève Hamelin and
  • Guy Boivin

19 February 2020

Human metapneumovirus (HMPV) is an important human pathogen that, along with respiratory syncytial virus (RSV), is a major cause of respiratory tract infections in young infants. Development of an effective vaccine against Pneumoviruses has proven to...

(This article belongs to the Special Issue Human Metapneumovirus Infection)
  • Article
  • Open Access
40 Citations
6,081 Views
12 Pages

19 February 2020

Although Corynebacterium striatum is part of the human flora, it has recently drawn attention both for its multidrug resistance and its role as an invasive infection/outbreak agent. This cross-sectional study aimed to determine the antimicrobial resi...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
18 Citations
4,890 Views
11 Pages

Comprehensive Evaluation of Hepatitis E Serology and Molecular Testing in a Large Cohort

  • Olympia E. Anastasiou,
  • Viktoria Thodou,
  • Annemarie Berger,
  • Heiner Wedemeyer and
  • Sandra Ciesek

19 February 2020

Introduction: Reliable and cost-effective diagnostics for hepatitis E virus (HEV) infection are necessary. The aim of our study was to investigate which diagnostic test is most accurate to detect HEV infection in immunocompetent and immunosuppressed...

(This article belongs to the Special Issue Hepatitis E Virus (HEV) Infections)
  • Review
  • Open Access
56 Citations
14,222 Views
21 Pages

18 February 2020

Porcine epidemic diarrhea virus (PEDV) is a highly virulent re-emerging enteric coronavirus that causes acute diarrhea, dehydration, and up to 100% mortality in neonatal suckling piglets. Despite this, a safe and effective PEDV vaccine against highly...

(This article belongs to the Section Immunological Responses and Immune Defense Mechanisms)
  • Article
  • Open Access
17 Citations
5,869 Views
12 Pages

Metabolic Changes of Mycobacterium tuberculosis during the Anti-Tuberculosis Therapy

  • Julia Bespyatykh,
  • Egor Shitikov,
  • Dmitry Bespiatykh,
  • Andrei Guliaev and ,
  • Ksenia Klimina,
  • Vladimir Veselovsky,
  • Georgij Arapidi,
  • Marine Dogonadze,
  • Viacheslav Zhuravlev and
  • Vadim Govorun
  • + 6 authors+ 1 author

18 February 2020

Tuberculosis, caused by Mycobacterium tuberculosis complex bacteria, remains one of the most pressing health problems. Despite the general trend towards reduction of the disease incidence rate, the situation remains extremely tense due to the distrib...

(This article belongs to the Special Issue Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment)
  • Article
  • Open Access
14 Citations
5,603 Views
16 Pages

18 February 2020

Epigenetic reprogramming in macrophages is termed trained innate immunity, which regulates immune tolerance and limits tissue damage during infection. Neisseria gonorrhoeae is a strict human pathogen that causes the sexually transmitted infection ter...

(This article belongs to the Special Issue Neisseria gonorrhoeae Infections)
  • Review
  • Open Access
45 Citations
7,871 Views
27 Pages

HPV Oncoproteins and the Ubiquitin Proteasome System: A Signature of Malignancy?

  • Anamaria Đukić,
  • Lucija Lulić,
  • Miranda Thomas,
  • Josipa Skelin and ,
  • Nathaniel Edward Bennett Saidu,
  • Magdalena Grce,
  • Lawrence Banks and
  • Vjekoslav Tomaić
  • + 3 authors+ 0 author

18 February 2020

Human papillomavirus (HPV) E6 and E7 oncoproteins are critical for development and maintenance of the malignant phenotype in HPV-induced cancers. These two viral oncoproteins interfere with a plethora of cellular pathways, including the regulation of...

(This article belongs to the Special Issue Viral-host interactions and determinants of human papillomavirus (HPV) life cycle and pathogenesis)
  • Review
  • Open Access
5 Citations
3,823 Views
7 Pages

18 February 2020

In the absence of a vaccine, current antibiotic-dependent efforts to reduce the prevalence of Neisseria gonorrhoeae in high prevalence populations have been shown to result in extremely high levels of antibiotic consumption. No randomized controlled...

(This article belongs to the Special Issue Neisseria gonorrhoeae Infections)
  • Article
  • Open Access
22 Citations
5,255 Views
14 Pages

Therapeutic Effects of Atranorin towards the Proliferation of Babesia and Theileria Parasites

  • Amany Magdy Beshbishy,
  • Gaber El-Saber Batiha,
  • Luay Alkazmi,
  • Eman Nadwa and ,
  • Eman Rashwan,
  • Ahmed Abdeen,
  • Naoaki Yokoyama and
  • Ikuo Igarashi
  • + 3 authors+ 0 author

17 February 2020

Atranorin (ATR), is a compound with multidirectional biological activity under different in vitro and in vivo conditions and it is effective as an antibacterial, antiviral, antiprotozoal and anti-inflammatory agent. In the current study, the in vitro...

  • Article
  • Open Access
11 Citations
5,317 Views
13 Pages

17 February 2020

Urinary schistosomiasis is a devastating parasitic disease in Nigeria. This study was carried out to investigate the current prevalence, intensity, risk factors and knowledge assessment among some rural communities in southwestern Nigeria. A cross-se...

(This article belongs to the Special Issue Prevalence of Strongyloidiasis and Schistosomiasis)
  • Brief Report
  • Open Access
8 Citations
4,843 Views
8 Pages

Foot-and-Mouth Disease Virus Lacking the Leader Protein and Containing Two Negative DIVA Markers (FMDV LL3B3D A24) Is Highly Attenuated in Pigs

  • Michael Eschbaumer,
  • Veronika Dill,
  • Jolene C. Carlson,
  • Jonathan Arzt and ,
  • Carolina Stenfeldt,
  • Peter W. Krug,
  • John M. Hardham,
  • Jacob E. Stegner,
  • Luis L. Rodriguez and
  • Elizabeth Rieder
  • + 5 authors+ 0 author

17 February 2020

Inactivated whole-virus vaccines are widely used for the control of foot-and-mouth disease (FMD). Their production requires the growth of large quantities of virulent FMD virus in biocontainment facilities, which is expensive and carries the risk of...

(This article belongs to the Special Issue Diagnostics, Vaccinology and Pathogenesis of Foot-and-Mouth Disease and Other Viral Vesicular Diseases of Livestock)
  • Article
  • Open Access
13 Citations
4,564 Views
17 Pages

Human Neutrophil Granule Exocytosis in Response to Mycobacterium smegmatis

  • Irina Miralda,
  • Christopher K. Klaes,
  • James E. Graham and
  • Silvia M. Uriarte

15 February 2020

Mycobacterium smegmatis rarely causes disease in the immunocompetent, but reported cases of soft tissue infection describe abscess formation requiring surgical debridement for resolution. Neutrophils are the first innate immune cells to accumulate at...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
38 Citations
5,496 Views
19 Pages

Ecology and Infection Dynamics of Multi-Host Amdoparvoviral and Protoparvoviral Carnivore Pathogens

  • Marta Canuti,
  • Melissa Todd,
  • Paige Monteiro,
  • Kalia Van Osch and ,
  • Richard Weir,
  • Helen Schwantje,
  • Ann P. Britton and
  • Andrew S. Lang
  • + 3 authors+ 0 author

15 February 2020

Amdoparvovirus and Protoparvovirus are monophyletic viral genera that infect carnivores. We performed surveillance for and sequence analyses of parvoviruses in mustelids in insular British Columbia to investigate parvoviral maintenance and cross-spec...

  • Review
  • Open Access
73 Citations
14,197 Views
26 Pages

Herpesviral Latency—Common Themes

  • Magdalena Weidner-Glunde,
  • Ewa Kruminis-Kaszkiel and
  • Mamata Savanagouder

15 February 2020

Latency establishment is the hallmark feature of herpesviruses, a group of viruses, of which nine are known to infect humans. They have co-evolved alongside their hosts, and mastered manipulation of cellular pathways and tweaking various processes to...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
77 Citations
11,578 Views
16 Pages

15 February 2020

Rhizosphere bacteria can positively influence plant growth by direct and indirect mechanisms. A total of 112 bacterial strains were isolated from the rhizosphere of rice and tested for plant beneficial activities such as siderophore production, cell-...

  • Article
  • Open Access
3 Citations
3,815 Views
19 Pages

14 February 2020

Enterovirus 71 (EV71) has become an important public health problem in the Asia-Pacific region in the past decades. EV71 infection might cause neurological and psychiatric complications and even death. Although an EV71 vaccine has been currently appr...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
23 Citations
4,999 Views
14 Pages

ZnO Nanoflower-Based NanoPCR as an Efficient Diagnostic Tool for Quick Diagnosis of Canine Vector-Borne Pathogens

  • Archana Upadhyay,
  • Huan Yang,
  • Bilal Zaman,
  • Lei Zhang and ,
  • Yundi Wu,
  • Jinhua Wang,
  • Jianguo Zhao,
  • Chenghong Liao and
  • Qian Han
  • + 4 authors+ 0 author

14 February 2020

Polymerase chain reaction (PCR) is a unique technique in molecular biology and biotechnology for amplifying target DNA strands, and is also considered as a gold standard for the diagnosis of many canine diseases as well as many other infectious disea...

(This article belongs to the Special Issue Canine and Feline Infectious Diseases)
  • Review
  • Open Access
53 Citations
10,858 Views
28 Pages

Potential of Bioremediation and PGP Traits in Streptomyces as Strategies for Bio-Reclamation of Salt-Affected Soils for Agriculture

  • Neli Romano-Armada,
  • María Florencia Yañez-Yazlle,
  • Verónica P. Irazusta,
  • Verónica B. Rajal and
  • Norma B. Moraga

13 February 2020

Environmental limitations influence food production and distribution, adding up to global problems like world hunger. Conditions caused by climate change require global efforts to be improved, but others like soil degradation demand local management....

  • Opinion
  • Open Access
35 Citations
8,048 Views
8 Pages

Human Metapneumovirus: A Largely Unrecognized Threat to Human Health

  • Charles J. Russell,
  • Rhiannon R. Penkert,
  • Sonnie Kim and
  • Julia L. Hurwitz

13 February 2020

Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening. High-risk populations include young children who are exposed to virus for the fir...

(This article belongs to the Special Issue Human Metapneumovirus Infection)
  • Article
  • Open Access
12 Citations
3,864 Views
8 Pages

The Mediterranean Mussel (Mytilus galloprovincialis) as Intermediate Host for the Anisakid Sulcascaris sulcata (Nematoda), a Pathogen Parasite of the Mediterranean Loggerhead Turtle (Caretta caretta)

  • Mario Santoro,
  • Erica Marchiori,
  • Marialetizia Palomba,
  • Barbara Degli Uberti and ,
  • Federica Marcer and
  • Simonetta Mattiucci
  • + 1 author+ 0 author

13 February 2020

Sulcascaris sulcata (Anisakidae), a pathogenic nematode of sea turtles, may cause ulcerous gastritis with different degrees of severity. Previous studies demonstrated a high prevalence of infection in the Mediterranean loggerhead turtle (Caretta care...

(This article belongs to the Special Issue Spontaneous Diseases of Mollusks)
  • Article
  • Open Access
43 Citations
5,625 Views
11 Pages

Dynamics of Classical Swine Fever Spread in Wild Boar in 2018–2019, Japan

  • Norikazu Isoda,
  • Kairi Baba,
  • Satoshi Ito,
  • Mitsugi Ito and ,
  • Yoshihiro Sakoda and
  • Kohei Makita
  • + 1 author+ 0 author

13 February 2020

The prolongation of the classic swine fever (CSF) outbreak in Japan in 2018 was highly associated with the persistence and widespread of the CSF virus (CSFV) in the wild boar population. To investigate the dynamics of the CSF outbreak in wild boar, s...

(This article belongs to the Special Issue Classical Swine Fever)
  • Article
  • Open Access
42 Citations
6,063 Views
16 Pages

Dynamic Network of Interactions in the Wildlife-Livestock Interface in Mediterranean Spain: An Epidemiological Point of View

  • Roxana Triguero-Ocaña,
  • Beatriz Martínez-López,
  • Joaquín Vicente,
  • José A. Barasona and ,
  • Jordi Martínez-Guijosa and
  • Pelayo Acevedo
  • + 1 author+ 0 author

13 February 2020

The correct management of diseases that are transmitted between wildlife and livestock requires a reliable estimate of the pathogen transmission rate. The calculation of this parameter is a challenge for epidemiologists, since transmission can occur...

(This article belongs to the Special Issue Tuberculosis Epidemiology and Control in Multi-Host Systems)
  • Article
  • Open Access
41 Citations
5,823 Views
15 Pages

Incidence, Pathotyping, and Antibiotic Susceptibility of Avian Pathogenic Escherichia coli among Diseased Broiler Chicks

  • Ashraf M. Awad,
  • Nahed A. El-Shall,
  • Doha S. Khalil,
  • Mohamed E. Abd El-Hack and ,
  • Ayman A. Swelum,
  • Ahmed H. Mahmoud,
  • Hossam Ebaid,
  • Ahmed Komany,
  • Reda H. Sammour and
  • Mahmoud E. Sedeik
  • + 5 authors+ 0 author

12 February 2020

A total of 54 broiler flocks during the first two weeks of life was used to investigate the incidence of avian pathogenic E. coli in Egypt; 28 isolates (51.85%) were revealed by colony morphology and biochemical identification which then investigated...

(This article belongs to the Section Animal Pathogens)
  • Article
  • Open Access
91 Citations
6,707 Views
11 Pages

Chrysin-Loaded Chitosan Nanoparticles Potentiates Antibiofilm Activity against Staphylococcus aureus

  • Busi Siddhardha,
  • Uday Pandey,
  • K. Kaviyarasu,
  • Rajasekharreddy Pala and ,
  • Asad Syed,
  • Ali H. Bahkali and
  • Abdallah M. Elgorban
  • + 2 authors+ 0 author

12 February 2020

The application of nanotechnology in medicine is gaining popularity due to its ability to increase the bioavailability and biosorption of numerous drugs. Chrysin, a flavone constituent of Orocylumineicum vent is well-reported for its biological prope...

  • Review
  • Open Access
44 Citations
7,594 Views
19 Pages

12 February 2020

Epstein–Barr virus (EBV) is involved in the pathogenesis of various lymphomas and carcinomas, whereas Kaposi’s sarcoma-associated herpesvirus (KSHV) participates in the pathogenesis of endothelial sarcoma and lymphomas. EBV and KSHV are r...

(This article belongs to the Special Issue Comparative Animal Models of Human Viral Infections)
  • Article
  • Open Access
12 Citations
5,680 Views
13 Pages

High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study

  • Ana Requena-Méndez,
  • Joaquin Salas-Coronas,
  • Fernando Salvador,
  • Joan Gomez-Junyent and ,
  • Judith Villar-Garcia,
  • Miguel Santin,
  • Carme Muñoz,
  • Ana González-Cordón,
  • Maria Teresa Cabezas Fernández and
  • Jose Muñoz
  • + 14 authors+ 9 authors

11 February 2020

Introduction: Strongyloidiasis is a prevailing helminth infection ubiquitous in tropical and subtropical areas, however, seroprevalence data are scarce in migrant populations, particularly for those coming for Asia. Methods: This study aims at evalua...

(This article belongs to the Special Issue Prevalence of Strongyloidiasis and Schistosomiasis)
  • Article
  • Open Access
13 Citations
3,543 Views
11 Pages

Molecular Detection and Genetic Characteristics of Equine Herpesvirus in Korea

  • Min-Goo Seo,
  • In-Ohk Ouh,
  • Sang Kyu Lee,
  • Jong-Seok Lee and ,
  • Oh-Deog Kwon and
  • Dongmi Kwak
  • + 1 author+ 0 author

11 February 2020

Respiratory diseases cause significant economic losses (especially in the horse racing industry). The present study describes the detection and genetic characteristics of equine herpesvirus (EHV) from a total of 1497 samples from clinically healthy h...

(This article belongs to the Section Animal Pathogens)
  • Article
  • Open Access
11 Citations
4,339 Views
13 Pages

Putative Role of a Yet Uncharacterized Protein Elicitor PeBb1 Derived from Beauveria bassiana ARSEF 2860 Strain against Myzus persicae (Homoptera: Aphididae) in Brassica rapa ssp. pekinensis

  • Talha Nazir,
  • Abdul Hanan,
  • Abdul Basit,
  • Muhammad Zeeshan Majeed and ,
  • Tauqir Anwar,
  • Iqra Nawaz and
  • Dewen Qiu
  • + 2 authors+ 0 author

11 February 2020

This study reports the characterization of protein elicitor PeBb1 derived from entomopathogenic fungus Beauveria bassiana ARSEF-2860 strain and its putative role in induced systemic resistance in Brassica rapa ssp. pekinensis against green peach aphi...

(This article belongs to the Special Issue Plant Resistance Induced by Microorganisms and Pathogens)
  • Article
  • Open Access
7 Citations
3,120 Views
13 Pages

Chlamydia pneumoniae Influence on Cytokine Production in Steroid-Resistant and Steroid-Sensitive Asthmatics

  • Dóra Paróczai,
  • Tímea Mosolygó,
  • Dávid Kókai,
  • Valéria Endrész and ,
  • Dezső P. Virok,
  • Attila Somfay and
  • Katalin Burián
  • + 2 authors+ 0 author

11 February 2020

Medications for asthma management consisting of inhaled corticosteroids act by controlling symptoms. However, some patients do not respond to steroid treatment due to immunological factors at the cytokine level. Chlamydia pneumoniae (C. pneumoniae) i...

  • Article
  • Open Access
8 Citations
4,784 Views
18 Pages

The Impact of Age and Sex on Mouse Models of Melioidosis

  • Christopher P. Klimko,
  • Sylvia R. Treviño,
  • Alicia M. Moreau,
  • Michael J. Aponte Cuadrado and ,
  • Joshua R. Meyer,
  • David P. Fetterer,
  • Susan L. Welkos,
  • Patricia L. Worsham,
  • Norman Kreiselmeier and
  • Christopher K. Cote
  • + 6 authors+ 1 author

11 February 2020

Mouse models have been used to generate critical data for many infectious diseases. In the case of Burkholderia pseudomallei, mouse models have been invaluable for bacterial pathogenesis studies as well as for testing novel medical countermeasures in...

(This article belongs to the Special Issue Animal Models of Infectious Disease)
  • Brief Report
  • Open Access
8 Citations
4,843 Views
7 Pages

Transient Transfection of the Zoonotic Parasite Babesia microti

  • Mingming Liu,
  • Shengwei Ji,
  • Mohamed Abdo Rizk,
  • Paul Franck Adjou Moumouni and ,
  • Eloiza May Galon,
  • Jixu Li,
  • Yongchang Li,
  • Weiqing Zheng,
  • Byamukama Benedicto and
  • Xuenan Xuan
  • + 7 authors+ 2 authors

10 February 2020

The development of genetic manipulation techniques has been reported in many protozoan parasites over the past few years. However, these techniques have not been established for Babesia microti. Here, we report the first successful transient transfec...

(This article belongs to the Section Human Pathogens)
  • Review
  • Open Access
  • Best Paper Award
292 Citations
24,847 Views
46 Pages

9 February 2020

The outbreaks of viral encephalopathy and retinopathy (VER), caused by nervous necrosis virus (NNV), represent one of the main infectious threats for marine aquaculture worldwide. Since the first description of the disease at the end of the 1980s, a...

(This article belongs to the Special Issue Viral Diseases of Fish)
  • Article
  • Open Access
18 Citations
5,517 Views
13 Pages

Effect and Analysis of Bacterial Lysates for the Treatment of Recurrent Urinary Tract Infections in Adults

  • Ricardo E. Ahumada-Cota,
  • Ulises Hernandez-Chiñas,
  • Feliciano Milián-Suazo,
  • María E. Chávez-Berrocal and ,
  • Armando Navarro-Ocaña,
  • Daniel Martínez-Gómez,
  • Genaro Patiño-López,
  • Erika P. Salazar-Jiménez and
  • Carlos A. Eslava
  • + 4 authors+ 0 author

6 February 2020

Urinary tract infection (UTI) is a relevant public health problem, economically and socially affecting the lives of patients. The increase of antimicrobial bacterial resistance significantly hinders the treatment of UTIs, raising the need to search f...

(This article belongs to the Section Vaccines and Therapeutic Developments)
  • Article
  • Open Access
10 Citations
4,107 Views
10 Pages

High Prevalence of Strongyloides among South Asian Migrants in Primary Care―Associations with Eosinophilia and Gastrointestinal Symptoms

  • Elinor Chloe Baker,
  • Damien K. Ming,
  • Yasmin Choudhury,
  • Shahedur Rahman and ,
  • Philip J. Smith,
  • Jose Muñoz,
  • Peter L. Chiodini,
  • Chris J. Griffiths,
  • Christopher J. M. Whitty and
  • Michael Brown
  • + 5 authors+ 0 author

6 February 2020

Gastrointestinal (GI) symptoms are a frequent reason for primary care consultation, and common amongst patients with strongyloidiasis. We conducted a prospective cohort and nested case control study in East London to examine the predictive value of a...

(This article belongs to the Special Issue Prevalence of Strongyloidiasis and Schistosomiasis)

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Pathogens - ISSN 2076-0817