- Feature Paper
- Article
PrPSc with Seeding Activity Extensively Overlaps with Proteinase-Resistant PrPSc Rather than Infectious PrPSc
- Yoshifumi Iwamaru,
- Yuichi Matsuura and
- Kohtaro Miyazawa
The disease-associated prion protein (PrPSc) has the ability to seed the conformational conversion of normal prion proteins into the amyloid fibril form. This prion seeding activity can be measured using an in vitro amplification assay termed real-ti...

