Human Metapneumovirus Infection

Dear Colleagues,

Human metapneumovirus (HMPV) is a clinically relevant single stranded RNA virus that belongs to the genus Metapneumovirus in the new virus family Pneumoviridae. Since its discovery in 2001, HMPV has been identified worldwide and it is considered to be one of the most significant causes of acute respiratory tract infection. The prevalence of HMPV infections is higher in infants and children than in adults. In fact, by the age of 5, almost all children have been exposed to HMPV. However, HMPV can also occur in adults of all ages, although increased severity of the disease is observed in the elderly and immunocompromised individuals. Despite the disease’s prevalence, there is no available commercial vaccine or specific treatment against HMPV. Given the extensive impact on human health, further studies are needed that identify the cellular and molecular mechanisms responsible for HMPV-induced disease.

For this Special Issue, we welcome submissions of original research and review articles, as well as short communications related to HMPV molecular and epidemiological aspects, virus–host interactions, replication, animal models, innate and adaptive immune response, and vaccine development. We look forward to your contribution.

Prof. Antonieta Guerrero-Plata
Guest Editor

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