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Journal of Personalized Medicine, Volume 12, Issue 2

February 2022 - 202 articles

Cover Story: Older people are more susceptible to anticholinergic effects on the central nervous system. In this paper, we develop a new scale (CALS) that includes 217 different drugs with anticholinergic properties. We observed an association between cognitive impairment and the anticholinergic burden when measured by CALS, but not when the ACB scale was applied. CALS can help to raise awareness among clinicians of the problems associated with the use of medications with anticholinergic effects and promote a better personalized pharmacological approach for each patient. View this paper
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Articles (202)

  • Article
  • Open Access
18 Citations
4,268 Views
27 Pages

Artificial Intelligence-Enabled Electrocardiogram Estimates Left Atrium Enlargement as a Predictor of Future Cardiovascular Disease

  • Yu-Sheng Lou,
  • Chin-Sheng Lin,
  • Wen-Hui Fang,
  • Chia-Cheng Lee,
  • Ching-Liang Ho,
  • Chih-Hung Wang and
  • Chin Lin

19 February 2022

Background: Left atrium enlargement (LAE) can be used as a predictor of future cardiovascular diseases, including hypertension (HTN) and atrial fibrillation (Afib). Typical electrocardiogram (ECG) changes have been reported in patients with LAE. This...

  • Article
  • Open Access
20 Citations
9,171 Views
18 Pages

Differences and Commonalities in Children with Childhood Apraxia of Speech and Comorbid Neurodevelopmental Disorders: A Multidimensional Perspective

  • Anna Maria Chilosi,
  • Irina Podda,
  • Ivana Ricca,
  • Alessandro Comparini,
  • Beatrice Franchi,
  • Simona Fiori,
  • Rosa Pasquariello,
  • Claudia Casalini,
  • Paola Cipriani and
  • Filippo Maria Santorelli

19 February 2022

Childhood apraxia of speech (CAS) is a motor speech disorder often co-occurring with language impairment and complex neurodevelopmental disorders. A cohort of 106 children with CAS associated to other neurodevelopmental disorders underwent a multidim...

  • Editorial
  • Open Access
3 Citations
3,211 Views
3 Pages

19 February 2022

Despite all the recent pharmacological advances and the introduction of targeted therapies in clinical practice, cancer still remains one of the leading cause of death, accounting for 10 million deaths per year, based on the most recent reports [...]

  • Article
  • Open Access
5 Citations
2,581 Views
13 Pages

MicroRNAs as Predictors of Future Uterine Malignancy in Endometrial Hyperplasia without Atypia

  • Chiao-Yun Lin,
  • Ren-Chin Wu,
  • Lan-Yan Yang,
  • Shih-Ming Jung,
  • Shir-Hwa Ueng,
  • Yun-Hsin Tang,
  • Huei-Jean Huang,
  • Hsiu-Jung Tung,
  • Cheng-Tao Lin and
  • Hsuan-Yu Chen
  • + 2 authors

18 February 2022

The histological criteria for classifying endometrial hyperplasia (EH) are based on architectural crowding and nuclear atypia; however, diagnostic agreement among pathologists is poor. We investigated molecular biomarkers of endometrial cancer (EC) r...

  • Article
  • Open Access
3,629 Views
9 Pages

Comparison of Long-Term Pneumonia Risk between Spleen Injury and Non-Spleen Injury after Total Splenectomy—A Population-Based Study

  • Chun-Cheng Lin,
  • Sheng-Der Hsu,
  • Wu-Chien Chien,
  • Chi-Hsiang Chung,
  • Cheng-Jueng Chen,
  • Chia-Ming Liang and
  • Zhi-Jie Hong

18 February 2022

Patients who undergo splenectomy are at a high risk of infection. We aimed to investigate the rate of pneumonia in patients who underwent splenectomy, specifically comparing those who had splenectomy due to spleen injury and those who had it for othe...

  • Article
  • Open Access
40 Citations
5,823 Views
17 Pages

COVID-19 Detection in CT/X-ray Imagery Using Vision Transformers

  • Mohamad Mahmoud Al Rahhal,
  • Yakoub Bazi,
  • Rami M. Jomaa,
  • Ahmad AlShibli,
  • Naif Alajlan,
  • Mohamed Lamine Mekhalfi and
  • Farid Melgani

18 February 2022

The steady spread of the 2019 Coronavirus disease has brought about human and economic losses, imposing a new lifestyle across the world. On this point, medical imaging tests such as computed tomography (CT) and X-ray have demonstrated a sound screen...

  • Article
  • Open Access
74 Citations
9,658 Views
23 Pages

A Multi-Agent Deep Reinforcement Learning Approach for Enhancement of COVID-19 CT Image Segmentation

  • Hanane Allioui,
  • Mazin Abed Mohammed,
  • Narjes Benameur,
  • Belal Al-Khateeb,
  • Karrar Hameed Abdulkareem,
  • Begonya Garcia-Zapirain,
  • Robertas Damaševičius and
  • Rytis Maskeliūnas

18 February 2022

Currently, most mask extraction techniques are based on convolutional neural networks (CNNs). However, there are still numerous problems that mask extraction techniques need to solve. Thus, the most advanced methods to deploy artificial intelligence...

  • Systematic Review
  • Open Access
17 Citations
4,037 Views
26 Pages

The Role of Robotic Visceral Surgery in Patients with Adhesions: A Systematic Review and Meta-Analysis

  • Marco Milone,
  • Michele Manigrasso,
  • Pietro Anoldo,
  • Anna D’Amore,
  • Ugo Elmore,
  • Mariano Cesare Giglio,
  • Gianluca Rompianesi,
  • Sara Vertaldi,
  • Roberto Ivan Troisi and
  • Nader K. Francis
  • + 1 author

18 February 2022

Abdominal adhesions are a risk factor for conversion to open surgery. An advantage of robotic surgery is the lower rate of unplanned conversions. A systematic review was conducted using the terms “laparoscopic” and “robotic”....

  • Article
  • Open Access
11 Citations
8,533 Views
14 Pages

Health Promotion and Disease Prevention in the Elderly: The Perspective of Nursing Students

  • Rogério Ferreira,
  • Cristina Lavareda Baixinho,
  • Óscar Ramos Ferreira,
  • Ana Clara Nunes,
  • Teresa Mestre and
  • Luís Sousa

18 February 2022

Health promotion and disease prevention are closely linked to health literacy. Therefore, intervention to increase individuals’ knowledge is essential if action is to be taken to promote a healthy lifestyle with support from health professional...

  • Article
  • Open Access
2 Citations
2,310 Views
10 Pages

18 February 2022

This nationwide, population-based, retrospective, matched case–control study included 4334 newly diagnosed Fuchs’ endothelial dystrophy (FED) patients who were identified by the International Classification of Diseases, Ninth Revision, Cl...

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J. Pers. Med. - ISSN 2075-4426