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Journal of Personalized Medicine, Volume 12, Issue 2

February 2022 - 202 articles

Cover Story: Older people are more susceptible to anticholinergic effects on the central nervous system. In this paper, we develop a new scale (CALS) that includes 217 different drugs with anticholinergic properties. We observed an association between cognitive impairment and the anticholinergic burden when measured by CALS, but not when the ACB scale was applied. CALS can help to raise awareness among clinicians of the problems associated with the use of medications with anticholinergic effects and promote a better personalized pharmacological approach for each patient. View this paper
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Articles (202)

  • Article
  • Open Access
2 Citations
2,478 Views
8 Pages

18 February 2022

Manipulation under anesthesia (MUA) for stiffness within 6 to 12 weeks after mechanically aligned total knee arthroplasty (TKA) generally yields better outcome scores than an MUA performed later. However, the timing of MUA after unrestricted, caliper...

  • Article
  • Open Access
5 Citations
3,534 Views
6 Pages

The Efficacy of Thrombin-Gelatin Matrix in Hemostasis for Large Breast Tumor after Vacuum-Assisted Breast Biopsy

  • Yen-Dun Tony Tzeng,
  • Shiuh-Inn Liu,
  • Being-Whey Wang,
  • Yu-Chia Chen,
  • Po-Ming Chang,
  • I-Shu Chen,
  • Jim Jinn-Chyuan Sheu and
  • Jui-Hu Hsiao

17 February 2022

Background: Vacuum-assisted breast biopsy (VABB) for benign breast tumor excision is a developing trend in breast surgery. The most common complication of VABB is hematoma. We assessed the efficiency of the thrombin-gelatin matrix (TGM) for hemostasi...

  • Article
  • Open Access
25 Citations
9,803 Views
14 Pages

17 February 2022

Chronic low back pain that lasts more than 12 weeks causes mental and physical distress. This study investigated the effects of pain neuroscience education combined with lumbar stabilization exercises on strength, pain, flexibility, and activity diso...

  • Article
  • Open Access
5 Citations
3,365 Views
10 Pages

Association between Hyperosmolar Hyperglycemic State and Venous Thromboembolism in Diabetes Patients: A Nationwide Analysis in Taiwan

  • Wei-Ting Wei,
  • Shu-Man Lin,
  • Jin-Yi Hsu,
  • Ying-Ying Wu,
  • Ching-Hui Loh,
  • Huei-Kai Huang and
  • Peter Pin-Sung Liu

17 February 2022

Background: Previous studies in Western countries have shown that a hyperosmolar hyperglycemic state (HHS) is associated with an increased risk of venous thromboembolism (VTE); in these cases, prophylactic anticoagulant treatment is suggested. Howeve...

  • Review
  • Open Access
7 Citations
3,584 Views
10 Pages

17 February 2022

In type 2 diabetes (T2D), there is a general and strong focus on carbohydrate restriction. However, this may have unwarranted consequences for those with concomitant chronic kidney disease (CKD) since decreasing intake of carbohydrates implies a high...

  • Article
  • Open Access
4 Citations
2,842 Views
11 Pages

17 February 2022

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally. Previous studies have addressed the impact of comorbidity on short-term mortality in patients with COPD. However, the prevalence of cardiovascular disease (CVD...

  • Systematic Review
  • Open Access
12 Citations
3,457 Views
18 Pages

17 February 2022

The superiority of second-generation cryoballoon (2G-CB) ablation versus contact force-sensing radiofrequency (CF-RF) ablation in patients with paroxysmal atrial fibrillation (AF) was assessed in this systematic review and meta-analysis. Freedom from...

  • Article
  • Open Access
7 Citations
2,665 Views
13 Pages

COVID-19 Vaccination Intention Associated with Behaviors towards Protection and Perceptions Regarding the Pandemic

  • Chrysoula Dafogianni,
  • Polyxeni Mangoulia,
  • Despoina Pappa,
  • Panagiota Xanthopoulou,
  • Ioannis Koutelekos,
  • Mixalis Zografakis-Sfakianakis,
  • Eftychia Ferentinou,
  • Antigoni Fountouki,
  • Marianna Drakopoulou and
  • Anna Giga
  • + 3 authors

17 February 2022

Background: The impressively rapid availability of different types of COVID-19 vaccines and, on the other hand, the degree of their effectiveness as opposed to the likelihood of serious or non-serious side effects place a fairly large percentage of t...

  • Article
  • Open Access
5 Citations
2,663 Views
11 Pages

Prediction of Gastric Gastrointestinal Stromal Tumors before Operation: A Retrospective Analysis of Gastric Subepithelial Tumors

  • Yu-Ning Lin,
  • Ming-Yan Chen,
  • Chun-Yi Tsai,
  • Wen-Chi Chou,
  • Jun-Te Hsu,
  • Chun-Nan Yeh,
  • Ta-Sen Yeh and
  • Keng-Hao Liu

17 February 2022

Gastrointestinal stromal tumors (GISTs), leiomyomas, and schwannomas are the most common gastric subepithelial tumors (GSETs) with similar endoscopic findings. Preoperative prediction of GSETs is difficult. This study analyzed and predicted GSET diag...

  • Communication
  • Open Access
3 Citations
2,526 Views
7 Pages

Electron Microscopy Reveals Evidence of Perinuclear Clustering of Mitochondria in Cardiac Biopsy-Proven Allograft Rejection

  • Estefanía Tarazón,
  • Lorena Pérez-Carrillo,
  • Manuel Portolés and
  • Esther Roselló-Lletí

17 February 2022

Acute cellular rejection is a major complication in heart transplantation. We focus on the analysis of new ultrastructural findings in cardiac biopsy rejection based on mitochondrial intracellular organization. This study includes heart transplanted...

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J. Pers. Med. - ISSN 2075-4426