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Diagnostics, Volume 11, Issue 3

March 2021 - 197 articles

Cover Story: Diagnosis of people infected with hepatitis C virus relies on results from serological and virological tests, which are optimized for plasma from venipuncture blood. Collection, storage, and transport of frozen plasma is not always possible, especially among vulnerable populations worldwide. In these settings, alternative specimen types, such as blood or plasma dried on filter paper, represent a potential option. This study evaluates the utility of the cobas® Plasma Separation Card for hepatitis C diagnosis and shows that dried plasma is useful as an alternative to plasma from venipuncture blood. View this paper
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Articles (197)

  • Review
  • Open Access
40 Citations
8,673 Views
13 Pages

Minimally Invasive Intracerebral Hemorrhage Evacuation Techniques: A Review

  • Theodore C. Hannah,
  • Rebecca Kellner and
  • Christopher P. Kellner

Intracerebral hemorrhage (ICH) continues to have high morbidity and mortality. Improving ICH outcomes likely requires rapid removal of blood from the parenchyma and restraining edema formation while also limiting further neuronal damage due to the su...

  • Article
  • Open Access
11 Citations
3,898 Views
12 Pages

Microstructural and Strength Changes in Trabecular Bone in Elderly Patients with Type 2 Diabetes Mellitus

  • Mercè Giner,
  • Cristina Miranda,
  • María Angeles Vázquez-Gámez,
  • Patricia Altea-Manzano,
  • María-José Miranda,
  • Antonio Casado-Díaz,
  • Ramón Pérez-Cano and
  • María-José Montoya-García

Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide and it is associated with an increased risk of osteoporosis and fragility fractures. Our aim is to analyze the effect of T2DM on bone quality. This is a case-control...

  • Article
  • Open Access
10 Citations
4,752 Views
17 Pages

Cognitive impairment (CI) is frequently present in multiple sclerosis patients. Despite ongoing research, the neurological substrates have not been fully elucidated. In this study we investigated the contribution of gray and white matter in the CI ob...

  • Interesting Images
  • Open Access
1 Citations
3,987 Views
3 Pages

Acute necrotizing encephalopathy is a devastating clinico-radiological syndrome characterized by fulminant neurological deterioration after an antecedent febrile illness, as well as the imaging hallmark of bilateral thalamic involvement. Herein, we d...

  • Article
  • Open Access
1 Citations
2,677 Views
14 Pages

Identification of Brain Damage after Seizures Using an MR-Based Electrical Conductivity Imaging Method

  • Sanga Kim,
  • Bup Kyung Choi,
  • Ji Ae Park,
  • Hyung Joong Kim,
  • Tong In Oh,
  • Won Sub Kang,
  • Jong Woo Kim and
  • Hae Jeong Park

Previous imaging studies have shown the morphological malformation and the alterations of ionic mobility, water contents, electrical properties, or metabolites in seizure brains. Magnetic resonance electrical properties tomography (MREPT) is a recent...

  • Article
  • Open Access
14 Citations
3,597 Views
9 Pages

Background: This retrospective observational study aims to assess the 5-year overall survival and the prognostic significance of risk factors of patients who underwent radical hysterectomy followed by adjuvant concurrent chemoradiation therapy (CCRT)...

  • Article
  • Open Access
38 Citations
9,209 Views
13 Pages

Oral Diagnostic Methods for the Detection of Periodontal Disease

  • Liza L. Ramenzoni,
  • Marc P. Lehner,
  • Manuela E. Kaufmann,
  • Daniel Wiedemeier,
  • Thomas Attin and
  • Patrick R. Schmidlin

Periodontitis is a common immune-inflammatory oral disease. Early detection plays an important role in its prevention and progression. Saliva is a reliable medium that mirrors periodontal health and is easily obtainable for identifying periodontal bi...

  • Review
  • Open Access
22 Citations
7,289 Views
16 Pages

Cystic Fibrosis-Related Diabetes (CFRD): Overview of Associated Genetic Factors

  • Fernanda Iafusco,
  • Giovanna Maione,
  • Francesco Maria Rosanio,
  • Enza Mozzillo,
  • Adriana Franzese and
  • Nadia Tinto

Cystic fibrosis (CF) is the most common autosomal recessive disease in the Caucasian population and is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that encodes for a chloride/bicarbonate channel expressed on the memb...

  • Review
  • Open Access
67 Citations
7,409 Views
15 Pages

Myocardial Work: Methodology and Clinical Applications

  • Konstantinos Papadopoulos,
  • Özge Özden Tok,
  • Konstantina Mitrousi and
  • Ignatios Ikonomidis

A precise and accurate assessment of left ventricular (LV) contractility is of utmost importance in terms of prognosis in most cardiac pathologies. Given the limitations of ejection fraction (EF) and global longitudinal strain (GLS) due to their load...

  • Article
  • Open Access
30 Citations
6,439 Views
13 Pages

Use of Machine Learning to Investigate the Quantitative Checklist for Autism in Toddlers (Q-CHAT) towards Early Autism Screening

  • Gennaro Tartarisco,
  • Giovanni Cicceri,
  • Davide Di Pietro,
  • Elisa Leonardi,
  • Stefania Aiello,
  • Flavia Marino,
  • Flavia Chiarotti,
  • Antonella Gagliano,
  • Giuseppe Maurizio Arduino and
  • Fabio Apicella
  • + 7 authors

In the past two decades, several screening instruments were developed to detect toddlers who may be autistic both in clinical and unselected samples. Among others, the Quantitative CHecklist for Autism in Toddlers (Q-CHAT) is a quantitative and norma...

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Diagnostics - ISSN 2075-4418