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Diagnostics, Volume 11, Issue 1

January 2021 - 146 articles

Cover Story: For decades, clinical attention to cachexia, often confused with anorexia, has been neglected. The diagnostic definition of cachexia itself has only recently been approved, which should help to avoid underestimation or mismanagement of this syndrome. Since then, the consensus definition of cachexia has constantly evolved (with growing importance given to functional and biochemical parameters to assess cachexia) and has even been finely tuned to distinguish its stages and degrees of severity. This review aims to pinpoint the major criteria to diagnose cachexia, highlighting the evolving importance of these criteria and distinguishing cachexia from other forms of muscle waste. View this paper.
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Articles (146)

  • Article
  • Open Access
1 Citations
2,709 Views
9 Pages

Feasibility and Safety of Transjugular Liver Biopsy for Japanese Patients with Chronic Liver Diseases

  • Makoto Iijima,
  • Takahiro Arisaka,
  • Akira Yamamiya,
  • Keiichi Tominaga,
  • Kazunori Nagashima,
  • Akira Kanamori,
  • Satoshi Masuyama,
  • Yuichi Majima,
  • Kenichi Goda and
  • Kazuyuki Ishida
  • + 1 author

Background and study aim: Transjugular liver biopsy (TJLB) can be used in patients who are ineligible for percutaneous liver biopsy (PLB) with acute and chronic hepatic disease. This study aimed to evaluate the usefulness and safety of TJLB in patien...

  • Article
  • Open Access
34 Citations
4,903 Views
14 Pages

Prediction of Nonalcoholic Fatty Liver Disease Using Noninvasive and Non-Imaging Procedures in Japanese Health Checkup Examinees

  • Kenichiro Murayama,
  • Michiaki Okada,
  • Kenichi Tanaka,
  • Chika Inadomi,
  • Wataru Yoshioka,
  • Yoshihito Kubotsu,
  • Tomomi Yada,
  • Hiroshi Isoda,
  • Takuya Kuwashiro and
  • Satoshi Oeda
  • + 9 authors

Access to imaging is limited for diagnosing nonalcoholic fatty liver disease (NAFLD) in general populations. This study evaluated the diagnostic performance of noninvasive and nonimaging indexes to predict NAFLD in the general Japanese population. He...

  • Article
  • Open Access
11 Citations
3,236 Views
11 Pages

Soluble ST2 as a Biomarker for Early Complications in Patients with Chronic Thromboembolic Pulmonary Hypertension Treated with Balloon Pulmonary Angioplasty

  • Marta Banaszkiewicz,
  • Arkadiusz Pietrasik,
  • Michał Florczyk,
  • Piotr Kędzierski,
  • Michał Piłka,
  • Rafał Mańczak,
  • Janusz Kochman,
  • Grzegorz Opolski,
  • Adam Torbicki and
  • Marcin Kurzyna
  • + 1 author

Background: The aim of the study was to assess soluble ST2 (sST2) concentration and its dynamic changes in the periprocedural period in patients with chronic thromboembolic pulmonary hypertension (CTEPH) treated with balloon pulmonary angioplasty (BP...

  • Review
  • Open Access
28 Citations
4,776 Views
16 Pages

Endoscopic Ultrasound vs. Computed Tomography for Gastric Cancer Staging: A Network Meta-Analysis

  • Bogdan Silviu Ungureanu,
  • Victor Mihai Sacerdotianu,
  • Adina Turcu-Stiolica,
  • Irina Mihaela Cazacu and
  • Adrian Saftoiu

Gastric cancer preoperative staging is of outmost importance to assure proper management of the disease. Providing a relevant clinical stage relies on different imaging methods such as computed tomography (CT) or endoscopic ultrasound (EUS). We aimed...

  • Article
  • Open Access
8 Citations
4,461 Views
15 Pages

Expression of Transcript Variants of PTGS1 and PTGS2 Genes among Patients with Chronic Rhinosinusitis with Nasal Polyps

  • Wioletta Pietruszewska,
  • Wojciech Fendler,
  • Marta Podwysocka,
  • Adam J. Białas,
  • Piotr Kuna,
  • Izabela Kupryś-Lipińska and
  • Maciej Borowiec

To date, there has been no reliable test to identify unfavorable course of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP), especially in aspirin intolerant patients. The research aimed to analyze the expression of transcript variants of PTGS1 and...

  • Article
  • Open Access
14 Citations
3,125 Views
12 Pages

Microperimetry and Optical Coherence Tomography Changes in Type-1 Diabetes Mellitus without Retinopathy

  • Elvira Orduna-Hospital,
  • Judit Otero-Rodríguez,
  • Lorena Perdices,
  • Ana Sánchez-Cano,
  • Ana Boned-Murillo,
  • Javier Acha and
  • Isabel Pinilla

Background: We aimed to measure and correlate inner retinal layer (IRL) thickness and macular sensitivity by optical coherence tomography (OCT) and by microperimetry, respectively, in type 1 diabetes mellitus patients (DM1) without diabetic retinopat...

  • Article
  • Open Access
13 Citations
3,761 Views
9 Pages

Kirsten rat sarcoma viral oncogene (KRAS) is the isoform most frequently mutated in human tumors. Testing for activating KRAS mutations has important implications for diagnosis and the personalized medicine of cancers. The current techniques for dete...

  • Article
  • Open Access
16 Citations
3,185 Views
9 Pages

Subclavian Vessel Compression Assessed by Duplex Scanning in Patients with Neurogenic Thoracic Outlet Syndrome and No Vascular Signs

  • Alban Fouasson-Chailloux,
  • Pierre Menu,
  • Pauline Daley,
  • Giovanni Gautier,
  • Guillaume Gadbled,
  • Pierre Abraham and
  • Marc Dauty

Neurogenic thoracic outlet syndrome (NTOS) is the most frequent form of TOS. It may affect both sides, but specific complementary exams are lacking. We aimed to evaluate duplex scanning results in a group of patients with unilateral or bilateral NTOS...

  • Review
  • Open Access
27 Citations
5,087 Views
17 Pages

Alteration of Postural Balance in Patients with Fibromyalgia Syndrome—A Systematic Review and Meta-Analysis

  • David Núñez-Fuentes,
  • Esteban Obrero-Gaitán,
  • Noelia Zagalaz-Anula,
  • Alfonso Javier Ibáñez-Vera,
  • Alexander Achalandabaso-Ochoa,
  • María del Carmen López-Ruiz,
  • Daniel Rodríguez-Almagro and
  • Rafael Lomas-Vega

Balance problems are one of the most frequent symptoms in patients with Fibromyalgia Syndrome (FMS). However, the extent and nature of this balance disorder are not known. The objective of this work was to determine the best evidence for the alterati...

  • Communication
  • Open Access
28 Citations
3,884 Views
9 Pages

COVID-19 in Pulmonary Artery Hypertension (PAH) Patients: Observations from a Large PAH Center in New York City

  • Roxana Sulica,
  • Frank Cefali,
  • Caroline Motschwiller,
  • Rebecca Fenton,
  • Anabela Barroso and
  • Daniel Sterman

Information on outcomes of COVID-19 in pulmonary arterial hypertension (PAH) patients is limited to a few case series and surveys. Here, we describe our experience at a large Pulmonary Hypertension Center in New York City at the height of the pandemi...

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Diagnostics - ISSN 2075-4418