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Diagnostics, Volume 10, Issue 12

December 2020 - 122 articles

Cover Story: Foot ulcers are a severe complication of diabetes mellitus. Laser speckle contrast imaging (LSCI) is a promising approach for diagnosis and prognosis. However, manual assessment during analysis of LSCI limits clinical applicability. An algorithm for semi-automatic analysis of LSCI data was developed and validated. We observed good to excellent agreement between the algorithm and manual assessment of the LSCI data. The algorithm delivers assessment of diabetic foot ulcers with a 10-fold workload reduction. This enhances the clinical applicability of LSCI for assessment of diabetic foot ulcers. View this paper
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Articles (122)

  • Article
  • Open Access
3 Citations
3,498 Views
14 Pages

Carotid Artery Plaque Identification and Display System (MRI-CAPIDS) Using Opensource Tools

  • Felipe P. Vista,
  • Minh Tri Ngo,
  • Seung Bin Cho,
  • Hyo Sung Kwak and
  • Kil To Chong

21 December 2020

Magnetic resonance imaging (MRI) represents one modality in atherosclerosis risk assessment, by permitting the classification of carotid plaques into either high- or low-risk lesions. Although MRI is generally used for observing the impact of atheros...

  • Review
  • Open Access
13 Citations
12,358 Views
11 Pages

Right Heart Size and Right Ventricular Reserve in Pulmonary Hypertension: Impact on Management and Prognosis

  • Ekkehard Grünig,
  • Christina A. Eichstaedt,
  • Rebekka Seeger and
  • Nicola Benjamin

21 December 2020

Various parameters reflecting right heart size, right ventricular function and capacitance have been shown to be prognostically important in patients with pulmonary hypertension (PH). In the advanced disease, patients suffer from right heart failure,...

  • Article
  • Open Access
23 Citations
6,638 Views
15 Pages

Deep Learning Assisted Localization of Polycystic Kidney on Contrast-Enhanced CT Images

  • Djeane Debora Onthoni,
  • Ting-Wen Sheng,
  • Prasan Kumar Sahoo,
  • Li-Jen Wang and
  • Pushpanjali Gupta

21 December 2020

Total Kidney Volume (TKV) is essential for analyzing the progressive loss of renal function in Autosomal Dominant Polycystic Kidney Disease (ADPKD). Conventionally, to measure TKV from medical images, a radiologist needs to localize and segment the k...

  • Interesting Images
  • Open Access
7 Citations
3,387 Views
6 Pages

Usefulness of 18f-FDG PET-CT in Staging, Restaging, and Response Assessment in Pediatric Rhabdomyosarcoma

  • Davide Donner,
  • Paola Feraco,
  • Linda Meneghello,
  • Barbara Rombi,
  • Lorena Picori and
  • Franca Chierichetti

21 December 2020

Rhabdomyosarcoma is the most common soft-tissue sarcoma of childhood. Despite clinical advances, subsets of these patients continue to suffer high morbidity and mortality rates associated with their disease. Following the European guidelines for 18F-...

  • Case Report
  • Open Access
5 Citations
2,751 Views
5 Pages

Dual TMPRSS2:ERG Fusion in a Patient with Lung and Prostate Cancers

  • Francesca Giunchi,
  • Francesco Massari,
  • Annalisa Altimari,
  • Elisa Gruppioni,
  • Elisabetta Nobili,
  • Michelangelo Fiorentino and
  • Andrea Ardizzoni

20 December 2020

The TMPRSS2:ERG fusion is considered prostate specific and has been rarely described in other tumors. We describe the case of a patient who developed lung and prostate cancers, both harboring the TMPRSS2:ERG fusion. The patient developed a cancer of...

  • Article
  • Open Access
7 Citations
3,871 Views
15 Pages

Prognostic Value of Admission Chest CT Findings for Invasive Ventilation Therapy in COVID-19 Pneumonia

  • Eva Gresser,
  • Johannes Rueckel,
  • Daniel Puhr-Westerheide,
  • Vincent Schwarze,
  • Nicola Fink,
  • Wolfgang G. Kunz,
  • Dietmar Wassilowsky,
  • Michael Irlbeck,
  • Jens Ricke and
  • Michael Ingrisch
  • + 1 author

19 December 2020

(1) Background: To assess the value of chest CT imaging features of COVID-19 disease upon hospital admission for risk stratification of invasive ventilation (IV) versus no or non-invasive ventilation (non-IV) during hospital stay. (2) Methods: A retr...

  • Article
  • Open Access
7 Citations
3,342 Views
12 Pages

COPD Imaging on a 3rd Generation Dual-Source CT: Acquisition of Paired Inspiratory-Expiratory Chest Scans at an Overall Reduced Radiation Risk

  • Joshua Gawlitza,
  • Thomas Henzler,
  • Frederik Trinkmann,
  • Elke Nekolla,
  • Holger Haubenreisser and
  • Gunnar Brix

18 December 2020

As stated by the Fleischner Society, an additional computed tomography (CT) scan in expiration is beneficial in patients with chronic obstructive pulmonary disease (COPD). It was thus the aim of this study to evaluate the radiation risk of a state-of...

  • Article
  • Open Access
7 Citations
4,476 Views
12 Pages

Pericapillary Edema Assessment by Means of the Nailfold Capillaroscopy and Laser Scanning Microscopy

  • Boris P. Yakimov,
  • Yury I. Gurfinkel,
  • Denis A. Davydov,
  • Anastasia S. Allenova,
  • Gleb S. Budylin,
  • Vladimir Yu. Vasiliev,
  • Vera Yu. Soldatova,
  • Armais A. Kamalov,
  • Simon T. Matskeplishvili and
  • Alexander V. Priezzhev
  • + 1 author

18 December 2020

Edema, i.e., fluid accumulation in the interstitial space, accompanies numerous pathological states of the human organism, including heart failure (HF), inflammatory response, and lymphedema. Nevertheless, techniques for quantitative assessment of th...

  • Article
  • Open Access
28 Citations
4,316 Views
10 Pages

Failure of Lactate Clearance Predicts the Outcome of Critically Ill Septic Patients

  • Raphael Romano Bruno,
  • Bernhard Wernly,
  • Stephan Binneboessel,
  • Philipp Baldia,
  • Dragos Andrei Duse,
  • Ralf Erkens,
  • Malte Kelm,
  • Behrooz Mamandipoor,
  • Venet Osmani and
  • Christian Jung

18 December 2020

Purpose: Early lactate clearance is an important parameter for prognosis assessment and therapy control in sepsis. Patients with a lactate clearance >0% might differ from patients with an inferior clearance in terms of intensive care management an...

  • Communication
  • Open Access
7 Citations
6,282 Views
6 Pages

17 December 2020

99mTc-dimercaptosuccinic acid (DMSA) scintigraphy is currently the method of choice for assessing renal scarring in children, but it is not established whether conducting the scan as a single photon emission tomography combined with low-dose CT (SPEC...

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Diagnostics - ISSN 2075-4418