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Cancers, Volume 16, Issue 11

June-1 2024 - 218 articles

Cover Story: Neoadjuvant chemotherapy (NAC) followed by tumor resection is crucial for treatment. The standard for evaluating NAC response is histological assessment using the modified Huvos classification, which has its limitations. Dynamic contrast-enhanced MRI (DCE-MRI) can visualize tumor properties such as perfusion and permeability. The relative wash-in rate (rWIR) correlates with histological response and reflects changes in tumor perfusion before and after NAC. This technique allows pre-resection prediction of NAC response and is a potential tool for treatment personalization. This multicenter retrospective study explores rWIR as a prognostic factor for clinical outcomes and its added value alongside known factors like age, tumor size, metastasis presence, histological response, and local recurrence. View this paper
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Articles (218)

  • Article
  • Open Access
2 Citations
2,156 Views
19 Pages

Cholesterol Dietary Intake and Tumor Cell Homeostasis Drive Early Epithelial Tumorigenesis: A Potential Modelization of Early Prostate Tumorigenesis

  • Marine Vialat,
  • Elissa Baabdaty,
  • Amalia Trousson,
  • Ayhan Kocer,
  • Jean-Marc A. Lobaccaro,
  • Silvère Baron,
  • Laurent Morel and
  • Cyrille de Joussineau

6 June 2024

Epidemiological studies point to cholesterol as a possible key factor for both prostate cancer incidence and progression. It could represent a targetable metabolite as the most aggressive tumors also appear to be sensitive to therapies designed to de...

  • Review
  • Open Access
7 Citations
4,318 Views
18 Pages

6 June 2024

Family communication has been thought to be an important area to support children’s adjustment to a cancer diagnosis. However, the characteristics of therapeutic parent–child communication that contribute to better patient outcomes and th...

  • Correction
  • Open Access
1,074 Views
2 Pages

Correction: Nam et al. Identification of Thiazolo[5,4-b]pyridine Derivatives as c-KIT Inhibitors for Overcoming Imatinib Resistance. Cancers 2023, 15, 143

  • Yunju Nam,
  • Chan Kim,
  • Junghee Han,
  • SeongShick Ryu,
  • Hanna Cho,
  • Chiman Song,
  • Nam Doo Kim,
  • Namkyoung Kim and
  • Taebo Sim

6 June 2024

The authors would like to make a correction to the previous article [...]

  • Article
  • Open Access
3 Citations
2,835 Views
24 Pages

Exploring the Survival Determinants in Recurrent Ovarian Cancer: The Role of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

  • Katarzyna Gęca,
  • Jakub Litwiński,
  • Tomasz Ostrowski,
  • Izabela Świetlicka,
  • Wojciech P. Polkowski and
  • Magdalena Skórzewska

5 June 2024

Background: Recurrent ovarian cancer (ROC) significantly challenges gynecological oncology due to its poor outcomes. This study assesses the impact of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) on ROC...

  • Article
  • Open Access
3 Citations
2,736 Views
10 Pages

A Clinical Perspective on Plasma Cell Leukemia: A Single-Center Experience

  • Andrew Y. Li,
  • Farin Kamangar,
  • Noa G. Holtzman,
  • Aaron P. Rapoport,
  • Mehmet H. Kocoglu,
  • Djordje Atanackovic and
  • Ashraf Z. Badros

5 June 2024

Circulating plasma cells (CPCs) are detected in most multiple myeloma (MM) patients, both at diagnosis and on relapse. A small subset, plasma cell leukemia (PCL), represents a different biology and has a poor prognosis. In this retrospective analysis...

  • Article
  • Open Access
9 Citations
2,707 Views
12 Pages

Spheno-Orbital Meningiomas: The Rationale behind the Decision-Making Process of Treatment Strategy

  • Giuseppe Mariniello,
  • Sergio Corvino,
  • Giuseppe Corazzelli,
  • Oreste de Divitiis,
  • Giancarlo Fusco,
  • Adriana Iuliano,
  • Diego Strianese,
  • Francesco Briganti and
  • Andrea Elefante

5 June 2024

Surgery stands as the primary treatment for spheno-orbital meningiomas, following a symptoms-oriented approach. We discussed the decision-making process behind surgical strategies through a review of medical records from 80 patients who underwent sur...

  • Article
  • Open Access
3 Citations
2,836 Views
15 Pages

Prognostic Significance of CD163+ and/or CD206+ Tumor-Associated Macrophages Is Linked to Their Spatial Distribution and Tumor-Infiltrating Lymphocytes in Breast Cancer

  • Canbin Fang,
  • Maisy Y. Cheung,
  • Ronald C. Chan,
  • Ivan K. Poon,
  • Conrad Lee,
  • Curtis C. To,
  • Julia Y. Tsang,
  • Joshua Li and
  • Gary M. Tse

5 June 2024

Tumor-associated macrophages (TAMs) is a key element in the breast tumor microenvironment. CD163 and CD206 have been utilized for TAM identification, but the clinical implications of TAMs identified by these markers have not been thoroughly explored....

  • Article
  • Open Access
4 Citations
2,696 Views
10 Pages

Lung Cancer and Air Quality in a Large Urban County in the United States

  • Hollis Hutchings,
  • Qiong Zhang,
  • Sue C. Grady,
  • Jessica Cox,
  • Andrew Popoff,
  • Carl P. Wilson,
  • Shangrui Zhu and
  • Ikenna Okereke

5 June 2024

Lung cancer is the leading cancer-related killer in the United States. The incidence varies geographically and may be affected by environmental pollutants. Our goal was to determine associations within time series for specific air pollutants and lung...

  • Article
  • Open Access
3 Citations
2,160 Views
8 Pages

5 June 2024

(1) Background: Recently, sodium–glucose cotransporter-2 inhibitors (SGLT2Is) have been reported to significantly reduce renal cell carcinoma (RCC) risk. However, the effect between individual SGLT2Is on RCC incidence in patients with type 2 di...

  • Article
  • Open Access
8 Citations
2,771 Views
20 Pages

Three-Dimension Epithelial Segmentation in Optical Coherence Tomography of the Oral Cavity Using Deep Learning

  • Chloe Hill,
  • Jeanie Malone,
  • Kelly Liu,
  • Samson Pak-Yan Ng,
  • Calum MacAulay,
  • Catherine Poh and
  • Pierre Lane

5 June 2024

This paper aims to simplify the application of optical coherence tomography (OCT) for the examination of subsurface morphology in the oral cavity and reduce barriers towards the adoption of OCT as a biopsy guidance device. The aim of this work was to...

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Cancers - ISSN 2072-6694