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Viruses, Volume 15, Issue 12

December 2023 - 176 articles

Cover Story: The antiviral factor Tetherin inhibits various enveloped viruses and is, therefore, counteracted by most of them to promote virus release. Previous studies revealed that SARS-CoV encodes two Tetherin antagonists: Spike (S) and ORF7a. Similarly, both proteins of SARS-CoV-2 were shown to partly influence Tetherin restriction. This work compared the abilities and mechanisms of S and ORF7a to counteract Tetherin. SARS-CoV-2 S and ORF7a reduced total exogenous Tetherin levels more efficiently than the respective counterparts derived from SARS-CoV. This ability was conserved among S proteins from different SARS-CoV-2 variants. Nevertheless, despite the presence of multiple Tetherin antagonists, SARS-CoV-2 replication in Caco-2 cells was further enhanced upon Tetherin knockout. View this paper
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Articles (176)

  • Article
  • Open Access
6 Citations
2,750 Views
20 Pages

StM171, a Stenotrophomonas maltophilia Bacteriophage That Affects Sensitivity to Antibiotics in Host Bacteria and Their Biofilm Formation

  • Ghadeer Jdeed,
  • Vera Morozova,
  • Yuliya Kozlova,
  • Artem Tikunov,
  • Tatyana Ushakova,
  • Alevtina Bardasheva,
  • Andrey Manakhov,
  • Maria Mitina,
  • Elena Zhirakovskaya and
  • Nina Tikunova

18 December 2023

Stenotrophomonas maltophilia mainly causes respiratory infections that are associated with a high mortality rate among immunocompromised patients. S. maltophilia exhibits a high level of antibiotic resistance and can form biofilms, which complicates...

  • Review
  • Open Access
13 Citations
5,952 Views
14 Pages

Hepatitis B in Healthcare Personnel: An Update on the Global Landscape

  • Georgia B. Nikolopoulou,
  • Ioannis Tzoutzas,
  • Athanasios Tsakris and
  • Helena C. Maltezou

18 December 2023

Despite the outstanding progress that has been made in the prevention, detection, and management of hepatitis B during the past decades, hepatitis B remains a problem among healthcare personnel (HCP) in many countries. We reviewed studies on all aspe...

  • Article
  • Open Access
9 Citations
2,184 Views
17 Pages

Emergence of Intergenogroup Reassortant G9P[4] Strains Following Rotavirus Vaccine Introduction in Ghana

  • Yen Hai Doan,
  • Francis Ekow Dennis,
  • Nobuhiro Takemae,
  • Kei Haga,
  • Hiroyuki Shimizu,
  • Michael Gyasi Appiah,
  • Belinda Larteley Lartey,
  • Susan Afua Damanka,
  • Takaya Hayashi and
  • Toshihiko Suzuki
  • + 3 authors

18 December 2023

Rotavirus (RVA) is a leading cause of childhood gastroenteritis. RVA vaccines have reduced the global disease burden; however, the emergence of intergenogroup reassortant strains is a growing concern. During surveillance in Ghana, we observed the eme...

  • Article
  • Open Access
3 Citations
3,521 Views
34 Pages

18 December 2023

Although COVID-19 transmission has been reduced by the advent of vaccinations and a variety of rapid monitoring techniques, the SARS-CoV-2 virus itself has shown a remarkable ability to mutate and persist. With this long track record of immune escape...

  • Review
  • Open Access
4 Citations
2,670 Views
11 Pages

17 December 2023

Background: Patients with chronic hepatitis C (CHC) and concomitant type 2 diabetes mellitus (DM) show a higher risk of developing hepatocellular carcinoma (HCC). Successful antiviral therapy has reduced the incidence of post-therapy HCC, but the pre...

  • Article
  • Open Access
1 Citations
2,613 Views
24 Pages

17 December 2023

Salmonid alphavirus strain 3 is responsible for outbreaks of pancreas disease in salmon and rainbow trout in Norway. Although the extensive amount of research on SAV3 focused mainly on the heart and pancreas (of clinical importance), tropism and path...

  • Article
  • Open Access
12 Citations
2,626 Views
16 Pages

Pathogenicity and Interspecies Transmission of Cluster 3 Tembusu Virus Strain TMUV HQ-22 Isolated from Geese

  • Qing Yang,
  • Yingying Ding,
  • Weiping Yao,
  • Shuyue Chen,
  • Yaqian Jiang,
  • Linping Yang,
  • Guangbin Bao,
  • Kang Yang,
  • Shinuo Fan and
  • Qingqing Du
  • + 2 authors

17 December 2023

Since 2010, the Tembusu virus (TMUV) has been highly prevalent in China, causing significant economic losses to the poultry industry. In 2022, a suspected outbreak of TMUV occurred at a goose farm located in Anhui Province. A strain of TMUV, TMUV HQ-...

  • Article
  • Open Access
2 Citations
2,692 Views
21 Pages

16 December 2023

Baloxavir marboxil (baloxavir) is an FDA-approved inhibitor of the influenza virus polymerase acidic (PA) protein. Here, we used next-generation sequencing to compare the genomic mutational profiles of IAV H1N1 and H3N2, and IBV wild type (WT) and mu...

  • Article
  • Open Access
6 Citations
3,571 Views
14 Pages

16 December 2023

Influenza antiviral drugs are important tools in our fight against both annual influenza epidemics and pandemics. Polyphenols are a group of compounds found in plants, some of which have demonstrated promising antiviral activity. Previous in vitro an...

  • Article
  • Open Access
9 Citations
3,180 Views
26 Pages

The Viromes of Six Ecosystem Service Provider Parasitoid Wasps

  • Gabriela B. Caldas-Garcia,
  • Vinícius Castro Santos,
  • Paula Luize Camargos Fonseca,
  • João Paulo Pereira de Almeida,
  • Marco Antônio Costa and
  • Eric Roberto Guimarães Rocha Aguiar

16 December 2023

Parasitoid wasps are fundamental insects for the biological control of agricultural pests. Despite the importance of wasps as natural enemies for more sustainable and healthy agriculture, the factors that could impact their species richness, abundanc...

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Viruses - ISSN 1999-4915