You are currently viewing a new version of our website. To view the old version click .

Viruses, Volume 13, Issue 11

November 2021 - 228 articles

Cover Story: Mayaro virus (MAYV) infection, often associated with joint pain, is becoming a considerable health issue that unfortunately lacks a specific antiviral treatment. In the present study, the potential of Favipiravir, a broad-spectrum antiviral drug, to inhibit MAYV replication in an immunocompetent mouse model was evaluated. The results showed that orally administrated with the drug at pre- or concurrent-MAYV infection, Favipiravir strongly decreased footpad swelling and infectious viral particles in the blood and organs. In post-treated MAYV-infected mice, the drug significantly reduced viral replication at the virus inoculated site. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (228)

  • Article
  • Open Access
22 Citations
5,032 Views
19 Pages

Exploring the Diversity of the Human Blood Virome

  • María Cebriá-Mendoza,
  • María A. Bracho,
  • Cristina Arbona,
  • Luís Larrea,
  • Wladimiro Díaz,
  • Rafael Sanjuán and
  • José M. Cuevas

21 November 2021

Metagenomics is greatly improving our ability to discover new viruses, as well as their possible associations with disease. However, metagenomics has also changed our understanding of viruses in general. The vast expansion of currently known viral di...

  • Article
  • Open Access
6 Citations
12,146 Views
18 Pages

Heterogeneity of Early Host Response to Infection with Four Low-Pathogenic H7 Viruses with a Different Evolutionary History in the Field

  • Gianpiero Zamperin,
  • Alice Bianco,
  • Jacqueline Smith,
  • Alessio Bortolami,
  • Lonneke Vervelde,
  • Alessia Schivo,
  • Andrea Fortin,
  • Sabrina Marciano,
  • Valentina Panzarin and
  • Eva Mazzetto
  • + 5 authors

21 November 2021

Once low-pathogenic avian influenza viruses (LPAIVs) of the H5 and H7 subtypes from wild birds enter into poultry species, there is the possibility of them mutating into highly pathogenic avian influenza viruses (HPAIVs), resulting in severe epizooti...

  • Article
  • Open Access
34 Citations
5,102 Views
8 Pages

Indications of Persistent Glycocalyx Damage in Convalescent COVID-19 Patients: A Prospective Multicenter Study and Hypothesis

  • Richard Vollenberg,
  • Phil-Robin Tepasse,
  • Kevin Ochs,
  • Martin Floer,
  • Markus Strauss,
  • Florian Rennebaum,
  • Iyad Kabar,
  • Alexandros Rovas and
  • Tobias Nowacki

21 November 2021

The COVID-19 pandemic is caused by the SARS CoV-2 virus and can lead to severe lung damage and hyperinflammation. In the context of COVID-19 infection, inflammation-induced degradation of the glycocalyx layer in endothelial cells has been demonstrate...

  • Article
  • Open Access
29 Citations
11,458 Views
19 Pages

Cross-Reactive Antibodies to SARS-CoV-2 and MERS-CoV in Pre-COVID-19 Blood Samples from Sierra Leoneans

  • Rodrigo Borrega,
  • Diana K. S. Nelson,
  • Anatoliy P. Koval,
  • Nell G. Bond,
  • Megan L. Heinrich,
  • Megan M. Rowland,
  • Raju Lathigra,
  • Duane J. Bush,
  • Irina Aimukanova and
  • Whitney N. Phinney
  • + 32 authors

21 November 2021

Many countries in sub-Saharan Africa have experienced lower COVID-19 caseloads and fewer deaths than countries in other regions worldwide. Under-reporting of cases and a younger population could partly account for these differences, but pre-existing...

  • Article
  • Open Access
5 Citations
3,757 Views
15 Pages

Characterization of Four Novel dsRNA Viruses Isolated from Mucor hiemalis Strains

  • Tünde Kartali,
  • Ildikó Nyilasi,
  • Sándor Kocsubé,
  • Roland Patai,
  • Tamás F. Polgár,
  • Nóra Zsindely,
  • Gábor Nagy,
  • László Bodai,
  • Zoltán Lipinszki and
  • Csaba Vágvölgyi
  • + 1 author

21 November 2021

We previously screened the total nucleic acid extracts of 123 Mucor strains for the presence of dsRNA molecules without further molecular analyses. Here, we characterized five novel dsRNA genomes isolated from four different Mucor hiemalis strai...

  • Review
  • Open Access
76 Citations
9,072 Views
20 Pages

The Roles of Neutrophils in Cytokine Storms

  • Lily Chan,
  • Negar Karimi,
  • Solmaz Morovati,
  • Kasra Alizadeh,
  • Julia E. Kakish,
  • Sierra Vanderkamp,
  • Fatemeh Fazel,
  • Christina Napoleoni,
  • Kimia Alizadeh and
  • Yeganeh Mehrani
  • + 3 authors

21 November 2021

A cytokine storm is an abnormal discharge of soluble mediators following an inappropriate inflammatory response that leads to immunopathological events. Cytokine storms can occur after severe infections as well as in non-infectious situations where i...

  • Article
  • Open Access
5 Citations
3,680 Views
20 Pages

21 November 2021

Across Africa, the Middle East, and Asia, peste des petits ruminants virus (PPRV) places a huge disease burden on agriculture, affecting, in particular, small ruminant production. The recent PPR outbreaks in Northern Africa, the European part of Turk...

  • Article
  • Open Access
7 Citations
3,687 Views
16 Pages

20 November 2021

Abalone amyotrophia is a viral disease that causes mass mortality of juvenile Haliotis discus and H. madaka. Although the cause of this disease has yet to be identified, we had previously postulated a novel virus with partial genome sequence similari...

  • Article
  • Open Access
2 Citations
3,030 Views
13 Pages

Functional Importance of Hydrophobic Patches on the Ebola Virus VP35 IFN-Inhibitory Domain

  • Nodoka Kasajima,
  • Keita Matsuno,
  • Hiroko Miyamoto,
  • Masahiro Kajihara,
  • Manabu Igarashi and
  • Ayato Takada

20 November 2021

Viral protein 35 (VP35) of Ebola virus (EBOV) is a multifunctional protein that mainly acts as a viral polymerase cofactor and an interferon antagonist. VP35 interacts with the viral nucleoprotein (NP) and double-stranded RNA for viral RNA transcript...

  • Communication
  • Open Access
8 Citations
4,581 Views
19 Pages

20 November 2021

A number of viruses, including Herpes Simplex Virus (HSV), West Nile Virus (WNV), La Crosse Virus (LACV), Zika virus (ZIKV) and Tick-borne encephalitis virus (TBEV), have the ability to gain access to the central nervous system (CNS) and cause severe...

of 23

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Viruses - ISSN 1999-4915