You are currently on the new version of our website. Access the old version .

Viruses, Volume 13, Issue 12

December 2021 - 219 articles

Cover Story: The archaeal caudovirus HF2 lytically infects Halorubrum coriense. Virus and host were isolated from a saltern crystallizer on the shore of Corio Bay, Australia. The viral genome (77,672 bp, dsDNA) has a compact and modular gene organization similar to many bacterial viruses. The functions of most genes are unknown. A series of intergenic repeat (IR) sequences were discovered that were conjectured to contain viral promoters, and in the current study, this was experimentally confirmed. Some IRs were active in both orientations. Apart from promoter motifs, IRs probably also contain binding sites for regulatory proteins. Viral transcripts were examined by reverse-transcriptase PCR (RT-PCR), which revealed transcripts (both sense and antisense) ranging from 1.1 kp to 35.8 kb. The results indicate a complex regulatory network in this and other members of the Haloferacalesvirus genus. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (219)

  • Article
  • Open Access
4 Citations
4,578 Views
16 Pages

Genomic Epidemiology of Salmonid Alphavirus in Norwegian Aquaculture Reveals Recent Subtype-2 Transmission Dynamics and Novel Subtype-3 Lineages

  • Daniel J. Macqueen,
  • Oliver Eve,
  • Manu Kumar Gundappa,
  • Rose Ruiz Daniels,
  • Michael D. Gallagher,
  • Svein Alexandersen and
  • Marius Karlsen

20 December 2021

Viral disease poses a major barrier to sustainable aquaculture, with outbreaks causing large economic losses and growing concerns for fish welfare. Genomic epidemiology can support disease control by providing rapid inferences on viral evolution and...

  • Article
  • Open Access
5 Citations
3,622 Views
20 Pages

Population Variability Generated during Rescue Process and Passaging of Recombinant Mumps Viruses

  • Anamarija Slović,
  • Tanja Košutić-Gulija,
  • Dubravko Forčić,
  • Maja Šantak,
  • Maja Jagušić,
  • Mirna Jurković,
  • Dorotea Pali and
  • Jelena Ivančić-Jelečki

20 December 2021

Recombinant mumps viruses (MuVs) based on established vaccine strains represent attractive vector candidates as they have known track records for high efficacy and the viral genome does not integrate in the host cells. We developed a rescue system ba...

  • Article
  • Open Access
2 Citations
3,478 Views
15 Pages

Protection against Congenital CMV Infection Conferred by MVA-Vectored Subunit Vaccines Extends to a Second Pregnancy after Maternal Challenge with a Heterologous, Novel Strain Variant

  • Claudia Fernández-Alarcón,
  • Grace Buchholz,
  • Heidi Contreras,
  • Felix Wussow,
  • Jenny Nguyen,
  • Don J. Diamond and
  • Mark R. Schleiss

20 December 2021

Maternal reinfection of immune women with novel human cytomegalovirus (HCMV) strains acquired during pregnancy can result in symptomatic congenital CMV (cCMV) infection. Novel animal model strategies are needed to explore vaccine-mediated protections...

  • Review
  • Open Access
80 Citations
18,298 Views
18 Pages

Prevention and Control Strategies of African Swine Fever and Progress on Pig Farm Repopulation in China

  • Yuanjia Liu,
  • Xinheng Zhang,
  • Wenbao Qi,
  • Yaozhi Yang,
  • Zexin Liu,
  • Tongqing An,
  • Xiuhong Wu and
  • Jianxin Chen

20 December 2021

African swine fever (ASF) is a devastating disease in domestic and wild pigs. Since the first outbreak of ASF in August 2018 in China, the disease has spread throughout the country with an unprecedented speed, causing heavy losses to the pig and rela...

  • Article
  • Open Access
24 Citations
4,683 Views
18 Pages

Microarray-Based Detection of Antibodies against SARS-CoV-2 Proteins, Common Respiratory Viruses and Type I Interferons

  • Elena Savvateeva,
  • Marina Filippova,
  • Vladimir Valuev-Elliston,
  • Nurana Nuralieva,
  • Marina Yukina,
  • Ekaterina Troshina,
  • Vladimir Baklaushev,
  • Alexander Ivanov and
  • Dmitry Gryadunov

20 December 2021

A microarray-based assay to detect IgG and IgM antibodies against betacoronaviruses (SARS-CoV-2, SARS, MERS, OC43, and HKU1), other respiratory viruses and type I interferons (IFN-Is) was developed. This multiplex assay was applied to track antibody...

  • Article
  • Open Access
7 Citations
4,050 Views
17 Pages

19 December 2021

Vaccination is considered the best strategy for limiting and eliminating the COVID-19 pandemic. The success of this strategy relies on the rate of vaccine deployment and acceptance across the globe. As these efforts are being conducted, the severe ac...

  • Case Report
  • Open Access
18 Citations
4,507 Views
10 Pages

Intrauterine Fetal Demise After Uncomplicated COVID-19: What Can We Learn from the Case?

  • Pavel Babal,
  • Lucia Krivosikova,
  • Lucia Sarvaicova,
  • Ivan Deckov,
  • Tomas Szemes,
  • Tatiana Sedlackova,
  • Michal Palkovic,
  • Anna Kalinakova and
  • Pavol Janega

19 December 2021

Background: SARS-CoV-2 infection in pregnant women can lead to placental damage and transplacental infection transfer, and intrauterine fetal demise is an unpredictable event. Case study: A 32-year-old patient in her 38th week of pregnancy reported l...

  • Article
  • Open Access
39 Citations
6,246 Views
14 Pages

Detection of Jingmenviruses in Japan with Evidence of Vertical Transmission in Ticks

  • Daisuke Kobayashi,
  • Ryusei Kuwata,
  • Toshiya Kimura,
  • Hiroshi Shimoda,
  • Ryosuke Fujita,
  • Astri Nur Faizah,
  • Izumi Kai,
  • Ryo Matsumura,
  • Yudai Kuroda and
  • Shumpei Watanabe
  • + 10 authors

19 December 2021

Jingmen tick virus (JMTV) and the related jingmenvirus-termed Alongshan virus are recognized as globally emerging human pathogenic tick-borne viruses. These viruses have been detected in various mammals and invertebrates, although their natural trans...

  • Communication
  • Open Access
7 Citations
3,930 Views
6 Pages

A Novel High-Throughput Nanopore-Sequencing-Based Strategy for Rapid and Automated S-Protein Typing of SARS-CoV-2 Variants

  • Gabriel E. Wagner,
  • Massimo G. Totaro,
  • André Volland,
  • Michaela Lipp,
  • Sabine Saiger,
  • Sabine Lichtenegger,
  • Patrick Forstner,
  • Dorothee von Laer,
  • Gustav Oberdorfer and
  • Ivo Steinmetz

19 December 2021

Rapid molecular surveillance of SARS-CoV-2 S-protein variants leading to immune escape and/or increased infectivity is of utmost importance. Among global bottlenecks for variant monitoring in diagnostic settings are sequencing and bioinformatics capa...

  • Protocol
  • Open Access
1 Citations
5,161 Views
15 Pages

LABRADOR—A Computational Workflow for Virus Detection in High-Throughput Sequencing Data

  • Izabela Fabiańska,
  • Stefan Borutzki,
  • Benjamin Richter,
  • Hon Q. Tran,
  • Andreas Neubert and
  • Dietmar Mayer

18 December 2021

High-throughput sequencing (HTS) allows detection of known and unknown viruses in samples of broad origin. This makes HTS a perfect technology to determine whether or not the biological products, such as vaccines are free from the adventitious agents...

of 22

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Viruses - ISSN 1999-4915