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Medicina, Volume 61, Issue 1

January 2025 - 166 articles

Cover Story: This study systematically reviewed and analyzed outcomes of robot-assisted radical prostatectomy (RARP), laparoscopic radical prostatectomy(LRP), and open radical prostatectomy (ORP) for prostate cancer. Key findings include the following: RARP had lower biochemical recurrence rates than ORP and LRP; fewer positive surgical margins versus ORP; similar continence rates but superior potency compared to ORP and LRP; and comparable blood loss as well as complication rates among all techniques. The operation time was longest for LRP. There was no difference in terms of operation time between RARP and ORP. Overall, RARP demonstrated better or equivalent oncologic, functional, and perioperative outcomes, suggesting its potential as a preferred approach. View this paper
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Articles (166)

  • Article
  • Open Access
2,096 Views
17 Pages
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Genomic Insights into Blood Pressure Regulation: Exploring Ion Channel and Transporter Gene Variations in Jordanian Hypertensive Individuals

  • Mansour Abdullah Alghamdi,
  • Laith AL-Eitan,
  • Rasheed Ibdah,
  • Islam Bani Khalid,
  • Salma Darabseh,
  • Maryam Alasmar and
  • Asaad Ataa
Medicina2025, 61(1), 156;https://doi.org/10.3390/medicina61010156

17 January 2025

Background and Objectives: Hypertension (HTN) constitutes a significant global health burden, yet the specific genetic variant responsible for blood pressure regulation remains elusive. This study investigates the genetic basis of hypertension in the...

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  • Article
  • Open Access
1,813 Views
12 Pages
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Systemic Lupus Erythematosus in Hemodialysis: Survival Comparison and Mortality-Related Factors

  • Hwajeong Lee and
  • Seok-Hui Kang
Medicina2025, 61(1), 155;https://doi.org/10.3390/medicina61010155

17 January 2025

Background and Objectives: We aimed to evaluate the outcome of systemic lupus erythematosus (SLE) patients undergoing hemodialysis (HD) by comparing the survival among HD patients with SLE, diabetes mellitus (DM), or other diseases in the Korean popu...

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  • Article
  • Open Access
1 Citations
4,067 Views
9 Pages
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Comparison of the Effects of Sugammadex Recommended Dose (2 mg/kg) and Fixed Dose of 200 mg on the Reversal of Moderate Neuromuscular Block and Recovery Profile in Adult Patients

  • Ji-Yoon Jung,
  • Sung-Ae Cho,
  • Woojin Kwon,
  • Hongwook Kim and
  • Tae-Yun Sung
Medicina2025, 61(1), 151;https://doi.org/10.3390/medicina61010151

17 January 2025

Background and Objectives: Neuromuscular blocking agents are essential to ensure optimal surgical conditions during general anesthesia. Sugammadex, a selective binding agent, is widely used to reverse neuromuscular blockade. While weight-based dosing...

Full Article
  • Review
  • Open Access
58 Citations
17,807 Views
12 Pages
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Enhancing Therapy Adherence: Impact on Clinical Outcomes, Healthcare Costs, and Patient Quality of Life

  • Urszula Religioni,
  • Rocío Barrios-Rodríguez,
  • Pilar Requena,
  • Mariola Borowska and
  • Janusz Ostrowski
Medicina2025, 61(1), 153;https://doi.org/10.3390/medicina61010153

17 January 2025

Adherence to therapy, defined as the extent to which a patient follows prescribed therapeutic recommendations, is a pivotal factor in the effective management of chronic diseases such as diabetes, hypertension, and cardiovascular conditions. This rev...

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  • Article
  • Open Access
1,684 Views
18 Pages
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Evaluating the Effectiveness of Cyclin-Dependent Kinase 4/6 Inhibitors in Early- and Very Early-Onset Metastatic Breast Cancer: A Multicenter Study

  • Akif Doğan,
  • Nurullah İlhan,
  • Goncagül Akdağ,
  • Sedat Yıldırım,
  • Mustafa Seyyar,
  • Zeynep Yüksel Yaşar,
  • Hande Nur Erölmez,
  • Heves Sürmeli,
  • Buğra Öztosun and
  • Özlem Nuray Sever
  • + 5 authors
Medicina2025, 61(1), 154;https://doi.org/10.3390/medicina61010154

17 January 2025

Background and Objectives: Early-onset breast cancer (EOBC), particularly in patients under 40, presents with distinct biological characteristics and worse survival outcomes compared to late-onset cases. Despite intensive treatments, EOBC p...

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  • Article
  • Open Access
2 Citations
2,006 Views
12 Pages
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Evaluation of Bone Mineral Metabolism in Pre-Dialysis Chronic Kidney Disease: Quantitative Computed Tomography vs. Dual-Energy Absorptiometry and Correlation with Bone Turnover Markers

  • Aydan Mutis Alan,
  • Zehra Sezer,
  • Ahmet Oz,
  • Cebrail Karaca,
  • Mevlüt Tamer Dinçer,
  • Ahmet Murt,
  • Fatma Beyza Sag,
  • Selma Alagoz,
  • Serdar Sahin and
  • Mustafa Sait Gonen
  • + 3 authors
Medicina2025, 61(1), 152;https://doi.org/10.3390/medicina61010152

17 January 2025

Background and Objectives: Bone and mineral disease (BMD) is a prevalent complication of advanced chronic kidney disease (CKD). The risk of fractures can be assessed via dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT...

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  • Article
  • Open Access
2 Citations
2,232 Views
15 Pages
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Retrospective Analysis of the Prevalence and Risk Factors of Retinopathy of Prematurity in a Single-Center Cohort in Romania and Comparison with National and European Data

  • Zsuzsánna Simon-Szabó,
  • Sándor Pál,
  • Aliz Pándi,
  • Zsuzsanna Gáll,
  • Hajnal Finta,
  • Zsuzsánna Incze-Bartha,
  • Cristina Maki and
  • Manuela Cucerea
Medicina2025, 61(1), 149;https://doi.org/10.3390/medicina61010149

17 January 2025

Background and Objectives: This study investigated and compared with European literature data the incidence, severity, and perinatal risk factors of retinopathy of prematurity (ROP) in preterm infants admitted to the Premature Department of Mureş...

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  • Article
  • Open Access
1 Citations
1,721 Views
12 Pages
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Association of Sociodemographic Variables and Healthy Habits with Body and Visceral Fat Values in Spanish Workers

  • María Gordito Soler,
  • Ángel Arturo López-González,
  • Pedro Juan Tárraga López,
  • Emilio Martínez-Almoyna Rifá,
  • Cristina Martorell Sánchez,
  • María Teófila Vicente-Herrero,
  • Hernan Paublini and
  • José Ignacio Ramírez-Manent
Medicina2025, 61(1), 150;https://doi.org/10.3390/medicina61010150

17 January 2025

Background and Objectives: The accumulation of fat in the body, especially visceral fat, is associated with various cardiometabolic conditions such as diabetes mellitus and fatty liver. The reasons for the accumulation of this fat are diverse. Some s...

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  • Article
  • Open Access
1 Citations
3,284 Views
13 Pages
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The Role of Butirprost® as an Adjuvant in Enhancing the Effect of Antibiotics in Patients Affected by Chronic Bacterial Prostatitis: A Randomized Prospective Trial

  • Felice Crocetto,
  • Armando Calogero,
  • Michele Santangelo,
  • Agostino Fernicola,
  • Filippo Varlese,
  • Benito Fabio Mirto,
  • Fabio Machiella,
  • Alfonso Falcone,
  • Giovanni Pagano and
  • Fabrizio Dinacci
  • + 11 authors
Medicina2025, 61(1), 148;https://doi.org/10.3390/medicina61010148

17 January 2025

Bacterial prostatitis (BP) is a common prostatic infection characterized by pain and urinary symptoms, often with negative bacterial cultures from prostatic secretions. It affects young and older men bimodally and impacts quality of life (QoL) signif...

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  • Article
  • Open Access
1,438 Views
14 Pages
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Relationship Between Perilesional Skin Condition and Survival in Terminally Ill Patients with Pressure Ulcers

  • María Isabel Pastor-Orduña,
  • Federico Palomar-Llatas,
  • David Palomar-Albert,
  • María Teresa Murillo-Llorente,
  • Ignacio Ventura,
  • Francisco Tomás-Aguirre and
  • Marcelino Pérez-Bermejo
Medicina2025, 61(1), 147;https://doi.org/10.3390/medicina61010147

17 January 2025

Background and Objectives: In the context of palliative care, the aim is to alleviate suffering and improve quality of life, with particular attention to PUs, which have a significant impact on quality of life and survival. This study examines the re...

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