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Medicina, Volume 59, Issue 8

August 2023 - 147 articles

Cover Story: Hepatocellular carcinoma is the leading cause of liver cancer worldwide, with a high incidence in patients with chronic liver diseases. The most resolutive treatment option, if applicable, is liver transplantation, while promising therapies such as immune checkpoint inhibitors are ineffective on some patients. A possible therapeutic strategy and future perspective of modern medicine is to restore the eubiosis of gut microbiota to enhance the efficacy of immunotherapy and use the microbiota fingerprint as a predictive biomarker. View this paper
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Articles (147)

  • Article
  • Open Access
4 Citations
4,821 Views
13 Pages

Specific Learning Disorders: Variation Analysis of 15 Candidate Genes in 9 Multiplex Families

  • Francesco Calì,
  • Francesco Domenico Di Blasi,
  • Emanuela Avola,
  • Mirella Vinci,
  • Antonino Musumeci,
  • Angelo Gloria,
  • Donatella Greco,
  • Daniela Rita Raciti,
  • Alessandro Zagami and
  • Biagio Rizzo
  • + 5 authors

21 August 2023

Background and Objectives: Specific Learning Disorder (SLD) is a complex neurobiological disorder characterized by a persistent difficult in reading (dyslexia), written expression (dysgraphia), and mathematics (dyscalculia). The hereditary and geneti...

  • Systematic Review
  • Open Access
8 Citations
3,879 Views
47 Pages

Doppler Indices of the Uterine, Umbilical and Fetal Middle Cerebral Artery in Diabetic versus Non-Diabetic Pregnancy: Systematic Review and Meta-Analysis

  • Sonja Perkovic-Kepeci,
  • Andja Cirkovic,
  • Natasa Milic,
  • Stefan Dugalic,
  • Dejana Stanisavljevic,
  • Milos Milincic,
  • Konstantin Kostic,
  • Nikola Milic,
  • Jovana Todorovic and
  • Ksenija Markovic
  • + 2 authors

21 August 2023

Background and Objectives: The aim of this study was to assess the differences in Doppler indices of the uterine (Ut), umbilical (UA), and middle cerebral artery (MCA) in diabetic versus non-diabetic pregnancies by conducting a comprehensive systemat...

  • Article
  • Open Access
4 Citations
3,756 Views
12 Pages

Is There an Association between Increased Stress and Smartphone Addiction? Insights from a Study on Medical Students from Saudi Arabia during the COVID-19 Pandemic

  • Haytham I. AlSaif,
  • Zeyad A. Alhozaimi,
  • Alhanouf S. Alrashed,
  • Kholoud S. Alanazi,
  • Mohammed G. Alshibani,
  • Turky H. Almigbal,
  • Saad M. Alsaad,
  • Abdullah A. Alrasheed and
  • Fahad D. Alosaimi

21 August 2023

Purpose: Smartphone addiction is prevalent among medical students, and there is a concern that the coronavirus disease 2019 (COVID-19) pandemic fueled a rise in smartphone addiction. Earlier studies suggest a link between excessive smartphone usage a...

  • Systematic Review
  • Open Access
5 Citations
5,063 Views
24 Pages

The Prevalence of Gastrointestinal Bleeding in COVID-19 Patients: A Systematic Review and Meta-Analysis

  • Eleni Karlafti,
  • Dimitrios Tsavdaris,
  • Evangelia Kotzakioulafi,
  • Adonis A. Protopapas,
  • Georgia Kaiafa,
  • Smaro Netta,
  • Christos Savopoulos,
  • Antonios Michalopoulos and
  • Daniel Paramythiotis

21 August 2023

Introduction: Severe acute respiratory syndrome coronavirus 2 caused the coronavirus disease of 2019 (COVID-19), which rapidly became a pandemic, claiming millions of lives. Apart from the main manifestations of this infection concerning the respirat...

  • Article
  • Open Access
2,088 Views
13 Pages

21 August 2023

Background and Objectives: The demand for permanent pacemaker (PPM) implantation for extremely old patients is increasing. Prior to implanting PPMs, life expectancy evaluation is essential but difficult. We aimed to develop and validate a scoring sys...

  • Review
  • Open Access
3 Citations
2,891 Views
13 Pages

Total Talar Prosthesis, Learning from Experience, Two Reports of Total Talar Prosthesis after Talar Extrusion and Literature Review

  • Danilo Leonetti,
  • Giorgio Carmelo Basile,
  • Gabriele Giuca,
  • Elena Corso,
  • Domenico Fenga and
  • Ilaria Sanzarello

21 August 2023

Recently, total talar prosthesis has been proposed to substitute the talus during the management of complex talar lesions such as talar extrusion, comminuted talar fractures, or avascular necrosis. Herein, we report two cases of talar extrusion treat...

  • Case Report
  • Open Access
2,510 Views
8 Pages

Using Single Peroneal Longus Tendon Graft for Segmental Meniscus Transplantation and Revision Anterior Cruciate Ligament Combined Anterolateral Reconstruction

  • Ling Yang,
  • Chih-Hao Chiu,
  • Kuo-Yao Hsu,
  • Chieh-An Chuang,
  • Alvin Chao-Yu Chen,
  • Yi-Sheng Chan and
  • Cheng-Pang Yang

21 August 2023

This case report describes a new approach to segmental meniscal reconstruction using a peroneal longus autograft in a patient with recurrent traumatic medial meniscus tear and anterior cruciate ligament reconstruction (ACLR) failure. While allograft...

  • Article
  • Open Access
4 Citations
2,433 Views
11 Pages

Feasibility and Efficacy of the Newly Developed Robotic Hybrid Assistive Limb Shoulder Exercises in Patients with C5 Palsy during the Acute Postoperative Phase

  • Shigeki Kubota,
  • Hideki Kadone,
  • Yukiyo Shimizu,
  • Hiroki Watanabe,
  • Masao Koda,
  • Yoshiyuki Sankai and
  • Masashi Yamazaki

21 August 2023

Background and Objectives: Although postoperative C5 palsy is a frequent complication of cervical spine surgery, no effective therapeutic rehabilitation approach has been established for postoperative C5 palsy. The purpose of this study was to find e...

  • Case Report
  • Open Access
2 Citations
3,112 Views
10 Pages

Sarcoidosis-Associated Sensory Ganglionopathy and Harlequin Syndrome: A Case Report

  • Ieva Navickaitė,
  • Miglė Ališauskienė,
  • Sandra Petrauskienė and
  • Gintarė Žemgulytė

20 August 2023

Background and Objectives: Sensory ganglionopathy is a rare neurological disorder caused by degeneration of the neurons composing the dorsal root ganglia. It manifests as various sensory disturbances in the trunk, proximal limbs, face, or mouth in a...

  • Article
  • Open Access
15 Citations
4,091 Views
16 Pages

The Carotid–Hyoid Topography Is Variable

  • Mihaela Daniela Manta,
  • Mugurel Constantin Rusu,
  • Sorin Hostiuc,
  • Alexandra Diana Vrapciu,
  • Bogdan Adrian Manta and
  • Adelina Maria Jianu

19 August 2023

Background and Objectives: The carotid bifurcation (CB) is presented in most anatomy textbooks as having a unique location at the upper margin of the thyroid cartilage. Although a number of case reports have provided evidence of the possibility of ca...

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Medicina - ISSN 1648-9144