Table of Contents
Int. J. Mol. Sci., Volume 18, Issue 5 (May 2017)
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Cover Story (view full-size image) The figure shows the molecular basis and principles of TSPO-PET imaging. The 18 kDa Translocator [...] Read more. The figure shows the molecular basis and principles of TSPO-PET imaging. The 18 kDa Translocator Protein (TSPO) is an outer mitochondrial membrane protein which is well-known to be over-expressed by microglia during activation, thus being a sensitive hallmark of neuroinflammation. PET-based molecular imaging techniques targeting neuroinflammation take advantage of this and are unique tools for the in vivo visualization and quantification of TSPO over-expression. View this paper.