Special Issue "Alterations to Signalling Pathways in Cancer Cells"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 May 2017) | Viewed by 74118
Interests: cell signaling; melanoma; photobiology; skin cancer; cell metabolism; melaninognesis; cell motility; ionizing radiation
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It is well acknowledged that in most transformed and tumour cells, that intracellular signalling pathways are altered to those observed in non-transformed cells. Considerable interest has been focused on understanding how these signalling pathways have been altered, and how these differences can be used to devise potential therapeutic treatments that may enhance survival rates of these cancer patients. In the area of melanoma research, a great deal of effort has been directed to understanding how those cells containing the BRAFV600E mutation can overcome treatment with specific inhibitors, such as vemurafenib. This Special Issue of the International Journal of Molecular Sciences, “Alterations to Signalling Pathways in Cancer Cells”, will focus on how intracellular signalling pathways are altered in tumour cells. Authors are invited to submit manuscripts that compare how these pathways differ to that seen in untransformed cells, and how they differ to that seen in untransformed cells or in tumour cells undergoing treatment. The results from these studies may provide useful information in devising treatments that may enhance survival rates of cancer patients.
Dr. Terrence Piva
Manuscript Submission Information
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- Tumour suppressor genes
- Cell survival