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Molecules, Volume 9, Issue 4

2004 April - 7 articles

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Articles (7)

  • Review
  • Open Access
15 Citations
16,016 Views
19 Pages

Mechanism-based Enzyme Inactivators of Phytosterol Biosynthesis

  • Wenxu Zhou,
  • Zhihong Song,
  • Ragu Kanagasabai,
  • Jialin Liu and ,
  • Pruthvi Jayasimha,
  • Archana Sinha,
  • Phani Veeramachanemi,
  • Mathew B. Miller and
  • W. David Nes
  • + 4 authors+ 0 author

31 March 2004

Current progress on the mechanism and substrate recognition by sterol methyl transferase (SMT), the role of mechanism-based inactivators, other inhibitors of SMT action to probe catalysis and phytosterol synthesis is reported. SMT is a membrane-bound...

  • Article
  • Open Access
114 Citations
19,372 Views
9 Pages

31 March 2004

In this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiol...

  • Article
  • Open Access
2 Citations
9,771 Views
10 Pages

Structure-Acidity-IR Spectra Correlations for p-Substituted N-Phenylsulfonylbenzamides†

  • Alexander Perjessy,
  • Walter M.F. Fabian,
  • Patrik Parik,
  • Miroslav Ludwig and ,
  • Dusan Loos and
  • Zora Sustekova
  • + 1 author+ 0 author

31 March 2004

The wavenumbers of the IR absorption bands of the C=O, S=O and N-H stretching vibrations for a series of p-substituted N-phenylsulfonylbenzamides were measured in trichloromethane. The bond orders, Mulliken charges, charge densities and heats of form...

  • Article
  • Open Access
8 Citations
9,487 Views
9 Pages

31 March 2004

2,3-Dichloroquinoxaline and some of its derivatives have been reacted with malononitrile and ethyl cyanoacetate to yield a variety of 3-chloro-2-(cyanomethylene)- 1,2-dihydroquinoxaline derivatives. The reaction of 3-chloro-2-(dicyanomethylene)-1,2-...

  • Article
  • Open Access
27 Citations
10,930 Views
9 Pages

31 March 2004

3-Alkyl(Aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) reacted with 2-furoyl chloride and thiophene-2-carbonyl chloride to afford the corresponding 3- alkyl(aryl)-4-(2-furoylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (3) and 3-alkyl(aryl)- 4-(...

  • Article
  • Open Access
9 Citations
9,748 Views
15 Pages

Reactions of Substituted Furan-2-carboxaldehydes and Furo[b]pyrrole Type Aldehydes with Benzothiazolium Salts

  • Zita Puterová,
  • Alžbeta Krutošíková,
  • Antonín Lyčka and
  • Tatiana Ďurčeková

31 March 2004

A series of new push-pull compounds were synthesised by reaction of 5-aryl- furan-2-carboxaldehydes and furo[b]pyrrole type aldehydes with benzothiazolium salts. These new condensation products represent highly conjugated systems that have potential...

  • Article
  • Open Access
4 Citations
9,995 Views
8 Pages

31 March 2004

The potassium salt of E- and Z-2,3-diphenylpropenoic acids prepared in situ could be esterified efficiently in DMSO with the appropriate alkyl halides at room temperature. In this way 10 previously undescribed esters of these acids were synthesised a...

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Molecules - ISSN 1420-3049