Pimelea poisoning of cattle is caused by the toxin simplexin present in native Pimelea plant species. Surface weathering and burial of Pimelea plant material under soil in Pimelea-infested pastures previously showed simplexin degradation, suggesting...
Pimelea poisoning of cattle is a unique Australian toxic condition caused by the daphnane orthoester simplexin present in native Pimelea pasture plants. Rumen microorganisms have been proposed to metabolise simplexin by enzymatic reactions, likely at...
Pimelea poisoning affects cattle grazing arid rangelands of Australia, has no known remedy and significant outbreaks can cost the industry $50 million per annum. Poisoning is attributable to consumption of native Pimelea plants containing the toxin s...
Four new eunicellin-based diterpenes, simplexins P–S (1–4), and the known compound simplexin A (5), have been isolated from the soft coral Klyxum simplex. The structures of the new metabolites were determined on the basis of extensive spectroscopic a...
Pimelea is a genus of about 140 plant species, some of which are well-known for causing animal poisoning resulting in significant economic losses to the Australian livestock industry. The main poisonous species/subspecies include Pimelea simplex (sub...
We found some errors in our previous published paper [1]. The structure of simplexin Q was found to be the same as klysimplexin C, previously published in Tetrahedron 2009, 65, 7016–7022 [2]. Also, simplexin S and a known compound cladieunicellin G,...
Pimelea poisoning in grazing cattle, also known as St George or Marree Disease, has been a long-time pestilence for the pastoral industry throughout arid regions of inland Australia. The causative species Pimelea (Thymelaeaceae), native to Queensland...
Cattle grazing the pastures of inland Australia can be poisoned by ingestion of certain native Pimelea plant species, particularly Pimelea trichostachya and Pimelea simplex. The Pimelea toxin, simplexin, causes often fatal restriction of the pulmonar...
In vibration insulation projects, a parameter affecting the dynamic properties of the viscoelastic materials is the previous static load acting on the supports, denominated here as the ‘preload’. Most of the currently-used methodologies o...
Pimelea is one of the highly toxic plants in Australia, particularly affecting cattle. It contains simplexin, a potent toxin that can cause Pimelea poisoning (St. George Disease) in livestock. A survey was conducted to assess the current impact of Pi...