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9 Results Found

  • Communication
  • Open Access
11 Citations
6,691 Views
10 Pages

OXA-48 Carbapenemase in Klebsiella pneumoniae Sequence Type 307 in Ecuador

  • José E. Villacís,
  • Jorge A. Reyes,
  • Hugo G. Castelán-Sánchez,
  • Sonia Dávila-Ramos and ,
  • Miguel Angel Lazo,
  • Ahmad Wali,
  • Luis A. Bodero,
  • Yadira Toapanta,
  • Cristina Naranjo and
  • Mónica C. Gestal
  • + 8 authors+ 3 authors

Antibiotic resistance is on the rise, leading to an increase in morbidity and mortality due to infectious diseases. Klebsiella pneumoniae is a Gram-negative bacterium that causes bronchopneumonia, abscesses, urinary tract infection, osteomyelitis, an...

(This article belongs to the Special Issue Infectious Diseases, New Approaches to Old Problems)
  • Article
  • Open Access
7 Citations
3,308 Views
9 Pages

The Genetic Characteristics and Carbapenem Resistance Mechanism of ST307 Klebsiella pneumoniae Coharbouring blaCMY-6, blaOXA-48, and a Truncated blaNDM-1

  • Qiucheng Shi,
  • Xinhong Han,
  • Qin Huang,
  • Yan Meng and ,
  • Ping Zhang,
  • Zhengan Wang,
  • Huangdu Hu,
  • Yan Jiang,
  • Xiaoxing Du and
  • Yunsong Yu
  • + 5 authors+ 0 author

13 November 2022

Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a common nosocomial pathogen causing severe infectious diseases, and ST307 CRKP is an emerging clone. In this study, we collected five ST307 CRKP isolates, evaluated their antimicrobial susceptibil...

(This article belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
  • Article
  • Open Access
8 Citations
4,239 Views
18 Pages

Carbapenemase-Producing Klebsiella pneumoniae in COVID-19 Intensive Care Patients: Identification of IncL-VIM-1 Plasmid in Previously Non-Predominant Sequence Types

  • Javier E. Cañada-García,
  • Eva Ramírez de Arellano,
  • Miguel Jiménez-Orellana,
  • Esther Viedma and ,
  • Aida Sánchez,
  • Almudena Alhambra,
  • Jennifer Villa,
  • Alberto Delgado-Iribarren,
  • Verónica Bautista and
  • Jesús Oteo-Iglesias
  • + 10 authors+ 5 authors

During the COVID-19 pandemic, intensive care units (ICUs) operated at or above capacity, and the number of ICU patients coinfected by nosocomial microorganisms increased. Here, we characterize the population structure and resistance mechanisms of car...

(This article belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
  • Article
  • Open Access
11 Citations
4,779 Views
13 Pages

Relevance of Next-Generation Sequencing in the Diagnosis of Thalassemia and Hemoglobinopathies: The Experience of Four Italian Diagnostic Hubs

  • Rita Selvatici,
  • Valentina Guida,
  • Massimo Maffei,
  • Milena Agata Irrera and ,
  • Alice Margutti,
  • Paola Bisceglia,
  • Massimo Mogni,
  • Erica Melchionda,
  • Giuseppina Stoico and
  • Cristina Curcio
  • + 15 authors+ 10 authors

27 December 2024

Thalassemias and hemoglobinopathies are among the most common genetic diseases worldwide and have a significant impact on public health. The decreasing cost of next-generation sequencing (NGS) has quickly enabled the development of new assays that al...

(This article belongs to the Section Bioinformatics)
  • Article
  • Open Access
9 Citations
3,220 Views
9 Pages

Molecular Genetic Epidemiology of an Emerging Antimicrobial-Resistant Klebsiella pneumoniae Clone (ST307) Obtained from Clinical Isolates in Central Panama

  • Virginia Núñez-Samudio,
  • Gumercindo Pimentel-Peralta,
  • Mellissa Herrera,
  • Maydelin Pecchio and ,
  • Johana Quintero and
  • Iván Landires
  • + 1 author+ 0 author

14 December 2022

Klebsiella pneumoniae has been among the main pathogens contributing to the burden of antimicrobial resistance (AMR) in the last decade, and K. pneumoniae AMR strains predominantly cluster in the ST258 clonal complex. However, ST307 is emerging as an...

  • Article
  • Open Access
6 Citations
3,090 Views
13 Pages

Population Structure and Genomic Characteristics of Australian Erysipelothrix rhusiopathiae Reveals Unobserved Diversity in the Australian Pig Industry

  • John Webster,
  • Bethany Bowring,
  • Leah Stroud,
  • Ian Marsh and ,
  • Narelle Sales and
  • Daniel Bogema
  • + 1 author+ 0 author

Erysipelothrix rhusiopathiae is a bacterial pathogen that is the causative agent of erysipelas in a variety of animals, including swine, emus, turkeys, muskox, caribou, moose, and humans. This study aims to investigate the population structure and ge...

(This article belongs to the Section Veterinary Microbiology)
  • Article
  • Open Access
15 Citations
3,361 Views
17 Pages

Genetic Characterization of Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates in a Tertiary Hospital in Greece, 2018–2022

  • Charalampos Zarras,
  • Theodoros Karampatakis,
  • Styliani Pappa,
  • Elias Iosifidis and ,
  • Eleni Vagdatli,
  • Emmanuel Roilides and
  • Anna Papa
  • + 2 authors+ 0 author

Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a serious public health issue. The study aimed to identify the antimicrobial resistance and accessory genes, the clonal relatedness, and the evolutionary dynamics of selected CRKP isola...

(This article belongs to the Special Issue Molecular Characterization of Gram-Negative Bacteria: Antimicrobial Resistance, Virulence and Epidemiology)
  • Article
  • Open Access
4 Citations
2,415 Views
15 Pages

29 July 2023

Objectives: Post-viral olfactory dysfunction (PVOD) is a neurogenic disorder caused by a common cold virus. Based on the homology of deduced amino acid sequences, olfactory sensory neurons (OSNs) in both mice and humans express either class I or clas...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
2 Citations
2,548 Views
15 Pages

Rapid Forensic DNA Profiling via Real-Time Recombinase Polymerase Amplification of InDel Markers

  • Liesl De Keyzer,
  • Sonja Škevin,
  • Koen Deserranno,
  • Dieter Deforce and
  • Filip Van Nieuwerburgh

6 February 2026

Forensic DNA profiling commonly relies on polymerase chain reaction (PCR) amplification followed by capillary electrophoresis (CE) or massively parallel sequencing (MPS), which requires expensive, laboratory-based equipment that depends on a stable p...

(This article belongs to the Section Biosensor and Bioelectronic Devices)