Infectious Diseases, New Approaches to Old Problems

Dear Colleagues,

Infectious diseases are one of the leading causes of death worldwide, and past and current efforts focus on its prevention and treatment, with the expectation of reducing the morbidity, mortality, and the associated economic burden. In 1940, life expectancy was 47 years of age (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354621/ ); however, with the appearance of antibiotics, life expectancy increased considerably, only to dramatically decrease, nowadays, as a result of the increase in antibiotic resistance. The distress of this new pandemic began in the human field several years ago; nevertheless, the concept of One Health has hallmarked the lack of prevention in control in other areas that have great implications in human health. Importantly, bacteria are not the only threat, with viruses and parasites also being a great hazard, and a challenge to prevent and treat. One common trait to most pathogens is their ability to modulate, manipulate, and escape host immune responses. Therefore, immunomodulation approaches, such as adjuvants, therapies, and vaccines, appear to be the most compelling methods to enhance an immune response, and appear to be highly promising.

This aim of this Special Issue is to unite several fields of the research to approach the problem from the One Health perspective. This Special Issue emerges as a result of the lack of strategies and solutions to overcome infectious diseases, in the framework of a technology and the interconnected world. This Issue will be also a platform to provide novel strategies for vaccine and therapeutic development, focusing on immunomodulation.

Dr. Eva Torres-Sangiao
Dr. Monica Cartelle Gestal
Guest Editors

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