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  • Article
  • Open Access
1 Citations
1,368 Views
11 Pages

The Challenge of a Recall Program from a Community-Based Hepatitis C Screening Campaign: The Effectiveness in HCV Microelimination

  • Cheng-Hung Chien,
  • Tien-Shin Chou,
  • Li-Wei Chen,
  • Chih-Lang Lin,
  • Jia-Jang Chang,
  • Ching-Jung Liu,
  • Shuo-Wei Chen,
  • Ching-Chih Hu and
  • Rong-Nan Chien

The optimal strategy for the microelimination of HCV within community settings remains ambiguous. We evaluated the percentage of participants who achieved linkage to care (LTC) following the conclusion of a screening campaign and examined the diverse...

  • Review
  • Open Access
2 Citations
2,750 Views
16 Pages

Microelimination of Hepatitis C in Thailand, Phetchabun Model: Progress, Challenges, and Future Directions

  • Yong Poovorawan,
  • Sitthichai Kanokudom,
  • Nungruthai Suntronwong,
  • Pornjarim Nilyanimit,
  • Ritthideach Yorsaeng,
  • Wijittra Phaengkha,
  • Napaporn Pimsing and
  • Chatree Jullapetch

3 June 2025

Hepatitis C virus (HCV) remains a global health challenge, contributing to chronic liver disease and hepatocellular carcinoma. In Thailand, HCV prevalence has declined from ~2% in the 1990s due to universal blood screening, harm reduction, and expand...

  • Brief Report
  • Open Access
4 Citations
2,053 Views
9 Pages

Viral Hepatitis C New Microelimination Pathways Objective: Psychiatric Communities HCV Free

  • Vito Fiore,
  • Andrea De Vito,
  • Agnese Colpani,
  • Valentina Manca,
  • Ivana Maida,
  • Giordano Madeddu and
  • Sergio Babudieri

13 November 2022

Background: People with psychiatric disorders have a high prevalence of HCV. For this reason, tailored interventions should be developed to reach this population. Methods: We performed a retrospective study on patients treated for HCV infection in ps...

  • Article
  • Open Access
1 Citations
532 Views
13 Pages

The Status of Hepatitis C Microelimination Among People Living with HIV in Central and Eastern Europe in 2022—Data from Euroguidelines in Central and Eastern Europe Network Group

  • Agata Skrzat-Klapaczyńska,
  • Sergii Antoniak,
  • Svitlana Antonyak,
  • Konstantinos Protopapas,
  • Antonios Papadopoulos,
  • Daniela Maric,
  • Botond Lakatos,
  • Antonija Verhaz,
  • Milan Zlamal and
  • Josip Begovac
  • + 8 authors

30 June 2025

Introduction: The implementation of nationwide viral hepatitis C elimination programs is challenging in Central and Eastern European countries (CEEC). It is reasonable to start by targeting specific populations, such as people living with HIV (PLWH),...

  • Article
  • Open Access
334 Views
12 Pages

Reaching the Unreachable: Hepatitis C virus (HCV) Microelimination in Prisons and Addiction Centers

  • Rui Gaspar,
  • Rui Morgado,
  • Jorge Tavares,
  • Paula Portela and
  • Guilherme Macedo

Background & Aims: Hepatitis C virus (HCV) infection remains one of the most significant and lethal infectious diseases worldwide. Since the approval of the first direct-acting antiviral agent in 2013, the therapeutic landscape has changed dramat...

  • Article
  • Open Access
5 Citations
2,932 Views
11 Pages

Micro-Elimination: Updated Pathway to Global Elimination of Hepatitis C in Small Communities and Industrial Settings during the COVID 19 Pandemic

  • Anca Elena Butaru,
  • Dan Ionuț Gheonea,
  • Ion Rogoveanu,
  • Mircea Diculescu,
  • Ancuța-Ramona Boicea,
  • Marius Bunescu,
  • Costin-Teodor Streba and
  • Carmen Nicoleta Oancea

27 October 2021

Background: In response to the goal of the World Health Organisation to eliminate hepatitis C virus infections by 2030, Romania is striving for national elimination. An already successful micro-elimination project was expanded to test-and-treat speci...

  • Article
  • Open Access
9 Citations
3,601 Views
13 Pages

Model of Care for Microelimination of Hepatitis C Virus Infection among People Who Inject Drugs

  • Francesco Giuseppe Foschi,
  • Alberto Borghi,
  • Alberto Grassi,
  • Arianna Lanzi,
  • Elvira Speranza,
  • Teo Vignoli,
  • Lucia Napoli,
  • Deanna Olivoni,
  • Michele Sanza and
  • on behalf of MITH Group
  • + 7 authors

3 September 2021

Background: People who inject drugs (PWID) are the largest group at risk for HCV infection. Despite the direct acting antivirals (DAA) advancements, HCV elimination has been hindered by real-life difficulties in PWID. Aims: This study aimed to assess...

  • Article
  • Open Access
9 Citations
2,891 Views
9 Pages

Hepatitis C Virus Micro-Elimination Plan in Southern Italy: The “HCV ICEberg” Project

  • Carmine Coppola,
  • Loreta A. Kondili,
  • Laura Staiano,
  • Simona Cammarota,
  • Anna Citarella,
  • Mirko Pio Aloisio,
  • Angelo Annunziata,
  • Francesca Futura Bernardi,
  • Aldo D’Avino and
  • Ugo Trama
  • + 6 authors

28 January 2023

This study evaluates the feasibility of a local action program for HCV micro-elimination in highly endemic areas. Retrospective analysis: administrative and laboratory data (Local Health Unit, southern Italy) were integrated to quantize the anti-HCV-...

  • Article
  • Open Access
11 Citations
4,004 Views
12 Pages

Hepatitis C Virus Prevalence and Risk Factors in a Village in Northeastern Romania—A Population-Based Screening—The First Step to Viral Micro-Elimination

  • Laura Huiban,
  • Carol Stanciu,
  • Cristina Maria Muzica,
  • Tudor Cuciureanu,
  • Stefan Chiriac,
  • Sebastian Zenovia,
  • Vladut Mirel Burduloi,
  • Oana Petrea,
  • Ana Maria Sîngeap and
  • Anca Trifan
  • + 3 authors

(1) Background: The World Health Organization adopted a strategy for the Global Health Sector on Viral Hepatitis in 2016, with the main objective of eliminating hepatitis C virus (HCV) by 2030. In this work, we aimed to evaluate the prevalence of HCV...

  • Review
  • Open Access
18 Citations
3,408 Views
15 Pages

HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons

  • Robert Flisiak,
  • Dorota Zarębska-Michaluk,
  • Egle Ciupkeviciene,
  • Sylvia Drazilova,
  • Sona Frankova,
  • Ivica Grgurevic,
  • Bela Hunyady,
  • Peter Jarcuska,
  • Limas Kupčinskas and
  • Adriana Vince
  • + 5 authors

26 February 2022

In 2016, the WHO announced a plan to eliminate viral hepatitis as a public health threat by 2030. In this narrative review, experts from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland and Slovakia assessed the feasibility o...

  • Article
  • Open Access
434 Views
13 Pages

The SCANVIR® Project: A Success in Hepatitis C Micro-Elimination in Nouvelle-Aquitaine

  • Sandrine Francois,
  • Gwennaick Villain,
  • Samy Yahiaoui,
  • Christine Silvain,
  • Brigitte Reiller,
  • Paul Carrier,
  • Sophie Alain,
  • Veronique Loustaud-Ratti and
  • Marilyne Debette-Gratien

23 January 2026

The SCANVIR® project is a regional initiative aimed at accelerating the elimination of hepatitis C virus (HCV) by reaching high-risk populations outside traditional healthcare settings. Launched in 2017 in Limoges and later expanded to Poitiers a...

  • Article
  • Open Access
2 Citations
1,681 Views
10 Pages

Differences in HCV Seroprevalence, Clinical Features, and Treatment Outcomes between Female and Male Incarcerated Population: Results from a Matched Cohort Study

  • Vito Fiore,
  • Andrea De Vito,
  • Elena Rastrelli,
  • Valentina Manca,
  • Giuseppe De Matteis,
  • Roberto Ranieri,
  • Emanuele Pontali,
  • Nicholas Geremia,
  • Sandro Panese and
  • Sergio Babudieri
  • + 2 authors

12 December 2023

Background: Women represent less than 5% of the incarcerated population in Italy, with very limited data on HCV infection. Higher HCV seroprevalence and active infection rates have been described among incarcerated females in available studies. Our a...

  • Article
  • Open Access
1 Citations
2,265 Views
16 Pages

HIV, HCV and HIV-HCV Coinfections in the General Population versus Inmates from Romania

  • Camelia Sultana,
  • Carmine Falanga,
  • Grațiana Chicin,
  • Laurențiu Ion,
  • Camelia Grancea,
  • Daniela Chiriac,
  • Adriana Iliescu and
  • Andrea Gori

10 August 2024

The objective of this study was to analyze the epidemiological links of the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and HIV-HCV coinfections to less studied types of transmission in certain populations. We performed an observation...

  • Article
  • Open Access
4 Citations
1,654 Views
14 Pages

HCV Cascade of Care in HIV/HCV Co-Infected Individuals: Missed Opportunities for Micro-Elimination

  • Christos Thomadakis,
  • Dimitrios Basoulis,
  • Olga Tsachouridou,
  • Konstantinos Protopapas,
  • Vasilios Paparizos,
  • Myrto Astriti,
  • Maria Chini,
  • Georgios Chrysos,
  • Markos Marangos and
  • Giota Touloumi
  • + 7 authors

30 May 2024

People living with HIV-HCV co-infection comprise a target group for HCV-micro-elimination. We conducted an HCV cascade of care (CoC) for HIV-HCV co-infected individuals living in Greece and investigated factors associated with different HCV-CoC stage...

  • Article
  • Open Access
12 Citations
3,228 Views
18 Pages

Resource Management through Artificial Intelligence in Screening Programs—Key for the Successful Elimination of Hepatitis C

  • Anca Elena Butaru,
  • Mădălin Mămuleanu,
  • Costin Teodor Streba,
  • Irina Paula Doica,
  • Mihai Mircea Diculescu,
  • Dan Ionuț Gheonea and
  • Carmen Nicoleta Oancea

Background: The elimination of the Hepatitis C virus (HCV) will only be possible if rapid and efficient actions are taken. Artificial neural networks (ANNs) are computing systems based on the topology of the biological brain, containing connected art...

  • Review
  • Open Access
5 Citations
1,862 Views
15 Pages

Facing HCV as a Major Public Healthcare Threat in Italy: Epidemiology and Micro-Elimination Pathways among Underserved Populations

  • Vito Fiore,
  • Valentina Manca,
  • Agnese Colpani,
  • Andrea De Vito,
  • Ivana Maida,
  • Giordano Madeddu and
  • Sergio Babudieri

Underserved populations have a wide heterogeneity on healthcare provision and use. They also represent the key populations according to WHO 2030 goals for HCV micro-elimination. Our review evaluated the available literature on HCV diagnosis, staging,...

  • Article
  • Open Access
522 Views
13 Pages

Low Prevalence of HCV Infection Among MSM in an Intervention for HCV Micro-Elimination in Rome Urges a Focus on High-Risk Behaviours

  • Pierluca Piselli,
  • Massimo Giuliani,
  • Massimo Farinella,
  • Rozenn Esvan,
  • Alessandra Latini,
  • Filippo Leserri,
  • Francesco Angeli,
  • Rosario Galipò,
  • Elisabetta Gennaro and
  • Enrico Girardi
  • + 13 authors

28 November 2025

Background/Objectives: The prevalence of Hepatitis C Virus (HCV) among men who have sex with men (MSM) is not negligible; however, data from Italy—especially regarding MSM who are not infected with Human Immunodeficiency Virus (HIV)—are l...

  • Article
  • Open Access
8 Citations
2,836 Views
12 Pages

Collaborative Referral Model to Achieve Hepatitis C Micro-Elimination in Methadone Maintenance Treatment Patients during the COVID-19 Pandemic

  • Chi-Ming Tai,
  • Chun-Kai Huang,
  • Te-Chang Changchien,
  • Po-Chun Lin,
  • Deng-Wu Wang,
  • Ting-Ting Chang,
  • Hsue-Wei Chan,
  • Tzu-Haw Chen,
  • Cheng-Hao Tseng and
  • Ming-Lung Yu
  • + 4 authors

27 July 2022

Although hepatitis C virus (HCV) prevails in patients receiving methadone maintenance treatment (MMT), most do not receive anti-HCV therapy. This single-center observational study aimed to achieve HCV micro-elimination at an MMT center during the COV...

  • Article
  • Open Access
11 Citations
3,425 Views
12 Pages

High Rates of Hidden HCV Infections among Hospitalized Patients Aged 55–85

  • Annarita Valeria Piazzolla,
  • Giulia Paroni,
  • Francesca Bazzocchi,
  • Mauro Cassese,
  • Antonio Cisternino,
  • Luigi Ciuffreda,
  • Franco Gorgoglione,
  • Leonardo Gorgoglione,
  • Vincenzo Palazzo and
  • Alessandra Mangia
  • + 15 authors

Background and Aims: The WHO has solicited all countries to eliminate HCV by 2030. The Italian government started routine screening for HCV infection in January 2021, initially targeting subjects born between 1969 and 1989. With the aim of achieving...

  • Project Report
  • Open Access
4 Citations
1,908 Views
13 Pages

Benchmarking of an Intervention Aiming at the Micro-Elimination of Hepatitis C in Vulnerable Populations in Perpignan, France, to Inform Scale-Up and Elimination on the French Territory

  • Gordana Avramovic,
  • Laura O’Doherty,
  • Tina McHugh,
  • Andre Jean Remy,
  • Arnaud Happiette,
  • Hakim Bouchkira,
  • Philippe Murat,
  • Olivier Scemama,
  • Adrien Esclade and
  • John S. Lambert
  • + 2 authors

21 October 2024

Hepatitis C virus (HCV) is an important cause of chronic liver disease. Among at-risk populations, access to care is challenging. The French Ministry of Health has supported a seek-and-treat pilot intervention aiming at micro-elimination in Perpignan...

  • Article
  • Open Access
13 Citations
3,520 Views
9 Pages

Strategy for the Micro-Elimination of Hepatitis C among Patients with Diabetes Mellitus—A Hospital-Based Experience

  • Pei-Yuan Su,
  • Yang-Yuan Chen,
  • Hsu-Heng Yen,
  • Siou-Ping Huang,
  • I-Ling Liu,
  • Ya-Huei Zeng,
  • Yu-Chun Hsu and
  • Fu-Yuan Siao

6 June 2021

Hepatitis C virus (HCV) infection can induce insulin resistance, and patients with diabetes mellitus (DM) have a higher prevalence of HCV infection. Patient outcomes improve after HCV eradication in DM patients. However, HCV micro-elimination targeti...

  • Article
  • Open Access
21 Citations
4,120 Views
12 Pages

Hepatitis C Micro-Elimination beyond Prison Walls: Navigator-Assisted Test-and-Treat Strategy for Subjects Serving Non-Custodial Sentences

  • Joaquin Cabezas,
  • Susana Llerena,
  • Miguel Mateo,
  • Rocío Álvarez,
  • Carmen Cobo,
  • Victoria González,
  • Elisa Martró,
  • Antonio Cuadrado and
  • Javier Crespo

Background and Aims: The Spanish prison population includes two groups: people in prison and those who are serving non-custodial sentences. The latter has not yet been studied. This study aims to describe this population and the results of a test-and...

  • Brief Report
  • Open Access
5 Citations
1,927 Views
6 Pages

Low Hepatitis C Virus Prevalence among Men Who Have Sex with Men Attending Public Health Services in The Netherlands

  • Stephanie Popping,
  • Sabine Haspels,
  • Hannelore M. Gotz,
  • W. C. J. P. M. van der Meijden,
  • Mark van den Elshout and
  • Bart J. Rijnders

25 November 2023

The hepatitis C virus (HCV) prevalence is high among men who have sex with men (MSM) with HIV in the Netherlands. Large reductions in HCV incidence among MSM with HIV, however, have occurred since treatment with direct-acting antivirals. Over the yea...

  • Article
  • Open Access
1 Citations
2,172 Views
13 Pages

Missed Opportunities: A Retrospective Study of Hepatitis C Testing in Hospital Inpatients

  • Christine Roder,
  • Carl Cosgrave,
  • Kathryn Mackie,
  • Bridgette McNamara,
  • Joseph S. Doyle and
  • Amanda J. Wade

18 June 2024

Increasing testing is key to achieving hepatitis C elimination. This retrospective study aimed to assess the testing cascade of patients at a regional hospital in Victoria, Australia, who inject drugs or are living with hepatitis C, to identify misse...

  • Article
  • Open Access
2,710 Views
14 Pages

Integration of Hepatitis C and Addiction Treatment in People Who Inject Drugs: The San Patrignano HCV-Free and Drug-Free Experience

  • Pierluca Piselli,
  • Antonio Boschini,
  • Romina Gianfreda,
  • Alessandra Nappo,
  • Claudia Cimaglia,
  • Gianpaolo Scarfò,
  • Camillo Smacchia,
  • Raffaella Paoletti,
  • Sarah Duehren and
  • Enrico Girardi

28 February 2024

Injection drug use represents an important contributor to hepatitis C virus (HCV) transmission, hence therapeutic communities (TCs) are promising points of care for the identification and treatment of HCV-infected persons who inject drugs (PWIDs). We...

  • Article
  • Open Access
8 Citations
3,213 Views
12 Pages

Hepatitis C Screening and Treatment Program in Hungarian Prisons in the Era of Direct Acting Antiviral Agents

  • Klára Werling,
  • Béla Hunyady,
  • Mihály Makara,
  • Krisztina Nemesi,
  • Gábor Horváth,
  • Ferenc Schneider,
  • Judit Enyedi,
  • Zsófia Müller,
  • Miklós Lesch and
  • Anna Nemes Nagy
  • + 6 authors

2 February 2022

A hepatitis C virus (HCV) screening and treatment program was conducted in Hungarian prisons on a voluntary basis. After HCV-RNA testing and genotyping for anti-HCV positives, treatments with direct-acting antiviral agents were commenced by hepatolog...

  • Article
  • Open Access
599 Views
13 Pages

Innovative Nurse-Led Community Health Centre–Corrections Partnership for Hepatitis C Testing and Treatment in Victoria, British Columbia

  • Marion Selfridge,
  • Tamara Barnett,
  • Lesley Munro,
  • Kiffer Card,
  • Sarah Nishimura,
  • Adam Beaumont,
  • Catherine Clarke,
  • Kellie Guarasci,
  • Karen Lundgren and
  • Chris Fraser
  • + 2 authors

6 December 2025

People who are incarcerated experience a high rate of hepatitis C (HCV) worldwide, and HCV micro-elimination in prisons is an effective strategy to support treatment. In Victoria, British Columbia, administrative barriers limited HCV testing and trea...

  • Article
  • Open Access
5 Citations
2,043 Views
9 Pages

14 January 2022

Background: Little is known about the use of an electronic reminder system for HCV screening among patients with kidney disease. In this study, we tried to determine whether reminder systems could improve the HCV screening rate in patients with kidne...

  • Article
  • Open Access
2,308 Views
14 Pages

Are We on the Right Track for HCV Micro-Elimination? HCV Management Practices in Dialysis Centers in Poland—A National Cross-Sectional Survey

  • Paulina Czarnecka,
  • Kinga Czarnecka,
  • Olga Tronina,
  • Teresa Baczkowska,
  • Weronika Zarychta-Wisniewska and
  • Magdalena Durlik

4 April 2023

Chronic hepatitis C (CHC) is prevalent in the hemodialysis-dependent population. Currently, all patients with CHC should be considered for treatment; however, many hemodialysis-dependent patients are still left untreated. Following HCV cure, accurate...

  • Review
  • Open Access
6 Citations
3,222 Views
14 Pages

Can Telemedicine Optimize the HCV Care Cascade in People Who Use Drugs? Features of an Innovative Decentralization Model and Comparison with Other Micro-Elimination Strategies

  • Riccardo Nevola,
  • Valerio Rosato,
  • Vincenza Conturso,
  • Pasquale Perillo,
  • Teresa Le Pera,
  • Ferdinando Del Vecchio,
  • Davide Mastrocinque,
  • Annalisa Pappalardo,
  • Simona Imbriani and
  • Ernesto Claar
  • + 2 authors

24 May 2022

People who use drugs (PWUDs) are a crucial population in the global fight against viral hepatitis. The difficulties in linkage to care, the low adherence to therapy, the frequent loss to follow-up and the high risk of re-infection make the eradicatio...

  • Article
  • Open Access
285 Views
13 Pages

20 February 2026

Background/Objectives: Chronic hepatitis B (HBV) and C (HCV) remain major public health challenges in Romania despite vaccination and antiviral therapy. Understanding infection patterns in different healthcare settings is essential for targeted elimi...