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14 Results Found

  • Article
  • Open Access

Tumor Growth Rate Predicts Pathological Outcomes in Breast Fibroepithelial Tumors: A Pilot Study and Review of Literature

  • Hisham F. Bahmad,
  • Adriana Falcon,
  • Abdallah Araji,
  • Karem Gharzeddine,
  • Youley Tjendra,
  • Elena F. Brachtel,
  • Natalie Pula,
  • Nicole Brofman,
  • Merce Jorda and
  • Carmen Gomez-Fernández

15 January 2026

Background/Objectives: Fibroepithelial tumors (FETs) of the breast, including fibroadenomas (FAs) and phyllodes tumors (PTs), are among the most common breast masses encountered by breast radiologists and pathologists. Differentiating FAs from benign...

  • Article
  • Open Access
3 Citations
3,542 Views
11 Pages

Computer-Aided Detection of Quantitative Signatures for Breast Fibroepithelial Tumors Using Label-Free Multi-Photon Imaging

  • Kana Kobayashi-Taguchi,
  • Takashi Saitou,
  • Yoshiaki Kamei,
  • Akari Murakami,
  • Kanako Nishiyama,
  • Reina Aoki,
  • Erina Kusakabe,
  • Haruna Noda,
  • Michiko Yamashita and
  • Yasutsugu Takada
  • + 1 author

Fibroadenomas (FAs) and phyllodes tumors (PTs) are major benign breast tumors, pathologically classified as fibroepithelial tumors. Although the clinical management of PTs differs from FAs, distinction by core needle biopsy diagnoses is still challen...

  • Review
  • Open Access
14 Citations
11,377 Views
11 Pages

Malignant Phyllodes Tumor of the Breast: A Practice Review

  • Ângelo Bezerra de Souza Fede,
  • Ronaldo Pereira Souza,
  • Mauricio Doi,
  • Marina De Brot,
  • Cynthia Aparecida Bueno de Toledo Osorio,
  • Guilherme Rocha Melo Gondim,
  • Jose Claudio Casali-da-Rocha,
  • Rima Jbili,
  • Almir Galvao Vieira Bitencourt and
  • Solange Moraes Sanches
  • + 2 authors

6 April 2021

Introduction: Phyllodes tumor (PT) of the breast, particularly malignant phyllodes tumor (mPT), is a rare fibroepithelial neoplasm. A complex diagnosis is based on pathologic, radiologic, and clinical findings, with controversies about what is the be...

  • Article
  • Open Access
11 Citations
3,980 Views
12 Pages

An Integrated Epigenomic and Genomic View on Phyllodes and Phyllodes-like Breast Tumors

  • Juergen Hench,
  • Tatjana Vlajnic,
  • Savas Deniz Soysal,
  • Ellen C. Obermann,
  • Stephan Frank and
  • Simone Muenst

28 January 2022

Fibroepithelial lesions (FL) of the breast, in particular, phyllodes tumors (PT) and fibroadenomas, pose a significant diagnostic challenge. There are no generally accepted criteria that distinguish benign, borderline, malignant PT and fibroadenomas....

  • Communication
  • Open Access
11 Citations
3,673 Views
11 Pages

Gene Expression Profiling of Fibroepithelial Lesions of the Breast

  • Xiaomo Li,
  • Eric Vail,
  • Horacio Maluf,
  • Manita Chaum,
  • Matthew Leong,
  • Joseph Lownik,
  • Mingtian Che,
  • Armando Giuliano,
  • Duoyao Cao and
  • Farnaz Dadmanesh

Fibroepithelial lesions of the breast (FELs) are a heterogeneous group of neoplasms exhibiting a histologic spectrum ranging from fibroadenomas (FAs) to malignant phyllodes tumors (PTs). Despite published histologic criteria for their classification,...

  • Review
  • Open Access
5 Citations
6,895 Views
12 Pages

Borderline Phyllodes Breast Tumors: A Comprehensive Review of Recurrence, Histopathological Characteristics, and Treatment Modalities

  • Fulvio Borella,
  • Mauro Porpiglia,
  • Niccolò Gallio,
  • Chiara Cito,
  • Lorenzo Boriglione,
  • Giulia Capella,
  • Paola Cassoni and
  • Isabella Castellano

Phyllodes tumors account for 2–3% of all fibroepithelial breast tumors and less than 1% of all breast cancers. These tumors are categorized into benign, borderline, or malignant based on cellular atypia, mitotic activity, and stromal overgrowth...

  • Review
  • Open Access
1,663 Views
15 Pages

Malignant Phyllodes Tumors: Diagnostic, Investigative and Therapeutic Challenges

  • Shuhei Suzuki,
  • Manabu Seino,
  • Hidenori Sato,
  • Masaaki Kawai,
  • Yosuke Saito,
  • Koki Saito,
  • Yuta Yamada,
  • Koshi Takahashi,
  • Ryosuke Kumanishi and
  • Tadahisa Fukui

Phyllodes tumors are rare fibroepithelial neoplasms of the breast, and their malignant forms present significant diagnostic and therapeutic challenges. This review summarizes current knowledge across the benign-to-malignant spectrum, focusing on diag...

  • Review
  • Open Access
863 Views
11 Pages

A Multidisciplinary Perspective on Breast Phyllodes Tumors: A Literature Review

  • Alexandru-Gratian Naum,
  • Andra-Mara Ursu,
  • Paloma Moisii,
  • Corina-Veronica Lupascu-Ursulescu,
  • Liliana Gheorghe and
  • Irina Jari

21 October 2025

Phyllodes tumors, also known as cystosarcoma phyllodes, represent a rare and complex category of fibroepithelial neoplasms that primarily affect the breast. These tumors are characterized by their unique histological architecture, which resembles lea...

  • Article
  • Open Access
11 Citations
3,549 Views
11 Pages

Clinico-Pathological Factors Determining Recurrence of Phyllodes Tumors of the Breast: The 25-Year Experience at a Tertiary Cancer Centre

  • Baijaeek Sain,
  • Arnab Gupta,
  • Aruni Ghose,
  • Sudip Halder,
  • Vishal Mukherjee,
  • Samir Bhattacharya,
  • Radha Raman Mondal,
  • Aditya Narayan Sen,
  • Bijan Saha and
  • Stergios Boussios

Background: Phyllodes tumors (PTs) of the breast are rare fibroepithelial tumors that are generally more prone to recurrence. Aims and objectives: This study aimed to assess the clinicopathological features, diagnostic modalities, and therapeutic int...

  • Systematic Review
  • Open Access
1 Citations
1,573 Views
16 Pages

Full-Thickness Chest Wall Resection and Reconstruction for Locally Invasive Phyllodes Tumors: A Systematic Review

  • Yun Sun Lim,
  • Ryan Tsui Hon Goh,
  • Breanna Wei Ning Ang,
  • Ailica Wan Xin Lee,
  • Eugene Kwong Fei Leong,
  • Lowell Leow,
  • Qin Xiang Ng and
  • Serene Si Ning Goh

8 June 2025

Background/Objectives: Phyllodes tumors (PTs) are rare fibroepithelial breast neoplasms with a high propensity for local recurrence, particularly in borderline and malignant forms. Although wide local excision with negative margins is standard, the r...

  • Communication
  • Open Access
2 Citations
2,608 Views
11 Pages

25 September 2023

Objective: Bladder lesions like urothelial carcinoma are rare in the first two decades of life. A biopsy of the bladder or urinary cytological examination is seldom required. Gross painless hematuria is the most relevant clinical syndrome. Methods: A...

  • Review
  • Open Access
40 Citations
5,219 Views
28 Pages

Cd34+ Stromal Cells/Telocytes in Normal and Pathological Skin

  • Lucio Díaz-Flores,
  • Ricardo Gutiérrez,
  • Maria Pino García,
  • Miriam González-Gómez,
  • Rosa Rodríguez-Rodriguez,
  • Nieves Hernández-León,
  • Lucio Díaz-Flores and
  • José Luís Carrasco

We studied CD34+ stromal cells/telocytes (CD34+SCs/TCs) in pathologic skin, after briefly examining them in normal conditions. We confirm previous studies by other authors in the normal dermis regarding CD34+SC/TC characteristics and distribution aro...

  • Review
  • Open Access
13 Citations
7,338 Views
14 Pages

Mimickers of Urothelial Carcinoma and the Approach to Differential Diagnosis

  • Claudia Manini,
  • Javier C. Angulo and
  • José I. López

25 February 2021

A broad spectrum of lesions, including hyperplastic, metaplastic, inflammatory, infectious, and reactive, may mimic cancer all along the urinary tract. This narrative collects most of them from a clinical and pathologic perspective, offering urologis...

  • Review
  • Open Access
11 Citations
5,991 Views
8 Pages

Malignant Phyllodes Tumor of the Breast and Pregnancy: A Rare Case Report and Literature Review

  • Laura Mustață,
  • Nicolae Gică,
  • Radu Botezatu,
  • Raluca Chirculescu,
  • Corina Gică,
  • Gheorghe Peltecu and
  • Anca Maria Panaitescu

26 December 2021

Phyllodes Tumor (PT) is a rare fibroepithelial breast tumor that can behave differently depending on its biologic features. Traditionally, PTs are classified by their histologic features into benign, borderline, and malignant. In most cases that were...