12 Results Found

The COVID-19 pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) increases the need for a rapid development of efficient vaccines. Among other vaccines in clinical trials, a recombinant VSV-∆G-spike vaccine was devel...

Microbial electrocatalysis reckons on microbes as catalysts for reactions occurring at electrodes. Microbial fuel cells and microbial electrolysis cells are well-known in this context; both prefer the oxidation of organic and inorganic matter for pro...

In the past 30 years, highly specific drugs, known as antibodies, have conquered the biopharmaceutical market. In addition to monoclonal antibodies (mAbs), antibody fragments are successfully applied. However, recombinant production faces challenges....

Significant progress in the manufacturing of biopharmaceuticals has been made by increasing the overall titers in the USP (upstream processing) titers without raising the cost of the USP. In addition, the development of platform processes led to a hi...

The bioconversion of lignocellulose and organic waste bagasse to lactic acid (LA) is an important alternative process requiring valorization as a potentially viable method in the production of pure LA, to be utilized for various purposes. Carob (Cera...

In this paper we present the simulative analysis of a 200 Gbps per wavelength (λ) 8-level pulse amplitude modulation (PAM-8) downstream communication over up to 20 km single mode fiber (SMF) in C-band based on direct detection (DD) achieving a...

Gag-based virus-like particles (VLPs) have high potential as scaffolds for the development of chimeric vaccines and delivery strategies. The production of purified preparations that can be preserved independently from cold chains is highly desirable...

Biopharmaceuticals are therapeutic drugs engineered to target specific sites within the body. Their manufacturing process comprises two primary stages: upstream processing (USP) and downstream processing (DSP). USP primarily involves cell culture and...

This study models two alternative downstream processes based on magnetic separation with the objective of understanding the economic feasibility of these processes compared to the traditional mAb process. The key focus lies in the economic understand...

Semiconductor optical amplifier (SOA) is considered an excellent candidate for power amplification at O-band due to its low cost and small footprint. In passive optical networks (PONs), SOA is popular as a booster and pre-amplifier to improve the lin...

Third-generation (3G) biorefineries harnessing industrial off-gases have received significant attention in the transition towards a sustainable circular economy. However, uncertainties surrounding their techno-economic feasibility are hampering wides...

This study investigates the impact of two comminution technologies—Vertical Shaft Impactors (VSI) and High-Pressure Grinding Rolls (HPGR)—on gold flotation performance, using ore samples from the Ballarat Gold Mine, Australia. The motivat...