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10 Results Found

  • Review
  • Open Access
1 Citations
5,757 Views
16 Pages

Recognition, Diagnosis, and Treatment of Clostridioides difficile Enterocolitis Presenting Without Diarrhea: A Literature Review

  • Ezgi Yılmaz,
  • Duygu Işıl Gencer,
  • Mustafa Salih Akın,
  • Meyha Şahin,
  • Bahadır Ceylan and
  • Ali Mert

12 February 2025

Diarrhea, as the well-known clinical feature of Clostridioides difficile infection (CDI), may be absent at the initial presentation, leading to delays in diagnosis. The delay is due to both underrecognition of such presentations and the dependence of...

(This article belongs to the Special Issue Clostridium Pathogenesis: Virulence, Host Responses, Microbiome, and Interventions)
  • Review
  • Open Access
14 Citations
4,356 Views
19 Pages

Clostridium difficile Induced Inflammasome Activation and Coagulation Derangements

  • Marta Mattana,
  • Riccardo Tomasello,
  • Claudia Cammarata,
  • Paola Di Carlo,
  • Teresa Fasciana,
  • Giulio Giordano,
  • Alessandro Lucchesi,
  • Sergio Siragusa and
  • Mariasanta Napolitano

C. difficile enterocolitis (CDAC) is the most common hospital infection, burdened by an increased incidence of coagulation-related complications such as deep vein thrombosis (DVT) and disseminated intravascular coagulation (DIC) as well as a signific...

(This article belongs to the Section Medical Microbiology)
  • Case Report
  • Open Access
545 Views
12 Pages

Fatal Systemic Infection Caused by Multidrug-Resistant Clostridioides difficile in a Domestic Rabbit: A Comprehensive Case Analysis

  • Vlad Iorgoni,
  • Livia Stanga,
  • Paula Nistor,
  • Ioan Cristian Dreghiciu,
  • Alexandru Gligor,
  • Bogdan Florea,
  • Janos Degi,
  • Ionica Iancu,
  • Horia Iorgoni and
  • Viorel Herman
  • + 2 authors

Background/Objectives: Rabbit farming in Romania is increasingly important for providing high-quality meat, yet productivity is frequently threatened by enteric diseases, particularly in young animals. Among bacterial etiologies, Clostridioides diffi...

(This article belongs to the Special Issue Challenges and Emerging Strategies to Tackle the Global Burden of Antimicrobial Resistance)
  • Article
  • Open Access
4 Citations
3,191 Views
7 Pages

Clinical Determinants Predicting Clostridioides difficile Infection among Patients with Chronic Kidney Disease

  • Łukasz Lis,
  • Andrzej Konieczny,
  • Michał Sroka,
  • Anna Ciszewska,
  • Kornelia Krakowska,
  • Tomasz Gołębiowski and
  • Zbigniew Hruby

The majority of recently published studies indicate a greater incidence rate and mortality due to Clostridioides difficile infection (CDI) in patients with chronic kidney disease (CKD). The aim of this study was to assess the clinical determinants pr...

(This article belongs to the Special Issue Clostridioides difficile Infection, 2nd Edition)
  • Article
  • Open Access
90 Citations
13,255 Views
13 Pages

Healthcare Associated Infections—A New Pathology in Medical Practice?

  • Septimiu Voidazan,
  • Sorin Albu,
  • Réka Toth,
  • Bianca Grigorescu,
  • Anca Rachita and
  • Iuliu Moldovan

Background: Hospital-acquired infections (HAI) contribute to the emotional stress and functional disorders of the patient and in some cases, can lead to a state of disability that reduces quality of life. Often, HAI are one of the factors that lead t...

(This article belongs to the Section Health Care Sciences & Services)
  • Article
  • Open Access
16 Citations
5,186 Views
12 Pages

Evaluating Healthcare-Associated Infections in Public Hospitals: A Cross-Sectional Study

  • Daniela Iancu,
  • Iuliu Moldovan,
  • Brîndușa Țilea and
  • Septimiu Voidăzan

2 December 2023

Background: Hospital-acquired infections (HAIs) pose a significant danger to global public health, mainly because their numbers are growing exponentially each year. Additionally, the rise of bacterial strains resistant to current treatment options fu...

(This article belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
  • Article
  • Open Access
4 Citations
2,521 Views
8 Pages

Predictive Factors for the First Recurrence of Clostridioides difficile Infection in the Elderly from Western Romania

  • Iosif Marincu,
  • Felix Bratosin,
  • Iulia Vidican,
  • Bianca Cerbu,
  • Mirela Turaiche,
  • Livius Tirnea and
  • Madalina Timircan

29 August 2020

Background and objectives: At present, Romania and parts of the European Union are facing an increasingly challenging public health problem consisting of nosocomial Clostridioides difficile infection (CDI), mostly in the elderly. Relapse cases have b...

(This article belongs to the Section Infectious Disease)
  • Review
  • Open Access
39 Citations
13,425 Views
21 Pages

Clostridial Diseases of Horses: A Review

  • Francisco A. Uzal,
  • Mauricio A. Navarro,
  • Javier Asin and
  • Eileen E. Henderson

17 February 2022

The clostridial diseases of horses can be divided into three major groups: enteric/enterotoxic, histotoxic, and neurotoxic. The main enteric/enterotoxic diseases include those produced by Clostridium perfringens type C and Clostridioides difficile, b...

  • Case Report
  • Open Access
528 Views
17 Pages

Renal Metastasis from Extrahepatic Cholangiocarcinoma Mimicking Renal Infarction: A Case Report and Literature Review

  • Mirela-Georgiana Perne,
  • Olga Hilda Orășan,
  • Cezara Andreea Gerdanovics,
  • Mircea Vasile Milaciu,
  • Călin Vasile Vlad,
  • Ioan Șimon,
  • Răzvan Togănel,
  • Nicolae Voicu Rednic,
  • Iuliana Georgiana Țifui and
  • Teodora Gabriela Alexescu
  • + 5 authors

Background: Cholangiocarcinoma (CCA) is a rare and aggressive malignancy of the biliary tree. Renal metastasis represents an exceptionally rare event, reported in fewer than 0.5% of cases. Its clinical and imaging presentation may closely mimic benig...

(This article belongs to the Special Issue Rare Cancers: Improving Diagnosis and Prognosis Through Collaborative Research)
  • Review
  • Open Access
692 Views
38 Pages

Nontoxigenic Bacteroides fragilis as a Next-Generation Probiotic: Mechanisms, Safety, and Therapeutic Potential

  • Dong Wang,
  • Zheng Nie,
  • Wenzheng Zhang,
  • Jinhui Liu,
  • Changqi Ge,
  • Yannan Zhang,
  • Yabin Lu,
  • Zhanhai Mai,
  • Xiaodong He and
  • Qingyong Guo
  • + 2 authors

Nontoxigenic Bacteroides fragilis (NTBF) is defined by the absence of the bft gene and corresponding B. fragilis toxin production; however, nontoxigenic status alone does not establish uniform safety or probiotic function. This review critically eval...

(This article belongs to the Special Issue Advances in Gut Microbiota–Host Interactions: Microbial Mechanisms, Modulators, and Translational Perspectives)