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11 Results Found

  • Article
  • Open Access
2 Citations
2,193 Views
8 Pages

No Association between the SORD Gene and Amyotrophic Lateral Sclerosis in a Chinese Cohort

  • Mubalake Yilihamu,
  • Ji He,
  • Lu Tang,
  • Yong Chen,
  • Xiaoxuan Liu and
  • Dongsheng Fan

18 November 2022

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. Recently a juvenile ALS patient was reported carrying the c.757delG mutation of the sorbitol dehydrogenase (SORD) gene, which was also a related mutation of Charcot-Marie-Toot...

  • Article
  • Open Access
12 Citations
3,415 Views
13 Pages

Serum Sorbitol Dehydrogenase as a Novel Prognostic Factor for Hepatocellular Carcinoma after Surgical Resection

  • Dongsub Jeon,
  • Won-Mook Choi,
  • Jin-Sun Kim,
  • Yusun Jung,
  • Su-Yeon Lee,
  • Haeng Ran Seo and
  • Kang Mo Kim

6 December 2021

The majority of patients with hepatocellular carcinoma (HCC) undergoing curative resection experience tumor recurrence. To examine the association between preoperative serum sorbitol dehydrogenase (SORD), a liver-derived enzyme that reflects liver da...

  • Article
  • Open Access
16 Citations
15,723 Views
17 Pages

The Role of Online Brand Community Engagement on the Consumer–Brand Relationship

  • Francisco J. Martínez-López,
  • Rocío Aguilar-Illescas,
  • Sebastián Molinillo,
  • Rafael Anaya-Sánchez,
  • J. Andres Coca-Stefaniak and
  • Irene Esteban-Millat

26 March 2021

The purpose of this study is to analyze the effects of online brand community (OBC) engagement on strategic aspects for the brand supporting the community. A total of 628 valid responses were collected through a self-administered questionnaire. The a...

  • Case Report
  • Open Access
1 Citations
2,916 Views
12 Pages

The Importance of Offering Exome or Genome Sequencing in Adult Neuromuscular Clinics

  • Laynie Dratch,
  • Tanya M. Bardakjian,
  • Kelsey Johnson,
  • Nareen Babaian,
  • Pedro Gonzalez-Alegre,
  • Lauren Elman,
  • Colin Quinn,
  • Michael H. Guo,
  • Steven S. Scherer and
  • Defne A. Amado

2 February 2024

Advances in gene-specific therapeutics for patients with neuromuscular disorders (NMDs) have brought increased attention to the importance of genetic diagnosis. Genetic testing practices vary among adult neuromuscular clinics, with multi-gene panel t...

  • Article
  • Open Access
16 Citations
2,860 Views
21 Pages

8 December 2022

Flower bud differentiation is crucial to reproductive success in plants. In the present study, RNA-Seq and nutrients quantification were used to identify the stage-specific genes for flower bud differentiation with buds which characterize the marked...

  • Review
  • Open Access
44 Citations
8,589 Views
14 Pages

29 October 2021

There is still no effective drug treatment available for Charcot-Marie-Tooth neuropathies (CMT). Current management relies on rehabilitation therapy, surgery for skeletal deformities, and symptomatic treatment of pain; fatigue and cramps are frequent...

  • Article
  • Open Access
17 Citations
5,362 Views
21 Pages

A hnRNP K–AR-Related Signature Reflects Progression toward Castration-Resistant Prostate Cancer

  • Matteo Capaia,
  • Ilaria Granata,
  • Mario Guarracino,
  • Andrea Petretto,
  • Elvira Inglese,
  • Carlo Cattrini,
  • Nicoletta Ferrari,
  • Francesco Boccardo and
  • Paola Barboro

The major challenge in castration-resistant prostate cancer (CRPC) remains the ability to predict the clinical responses to improve patient selection for appropriate treatments. The finding that androgen deprivation therapy (ADT) induces alterations...

  • Article
  • Open Access
13 Citations
2,671 Views
18 Pages

QTLs and Candidate Genes Associated with Semen Traits in Merino Sheep

  • Marnie J. Hodge,
  • Sara de las Heras-Saldana,
  • Sally J. Rindfleish,
  • Cyril P. Stephen and
  • Sameer D. Pant

12 July 2023

Ram semen traits play a significant role in conception outcomes, which in turn may influence reproductive efficiency and the overall productivity and profitability of sheep enterprises. Since hundreds of ewes may be inseminated from a single ejaculat...

  • Article
  • Open Access
2 Citations
3,163 Views
13 Pages

Designers Drugs—A New Challenge to Emergency Departments—An Observational Study in Poland

  • Rakesh Jalali,
  • Paula Dmochowska,
  • Izabela Godlewska,
  • Justyna Balmas,
  • Katarzyna Młynarska,
  • Krzysztof Narkun,
  • Andrzej Zawadzki and
  • Marcin Wojnar

17 July 2020

Background and Objective: In the last decade, the phenomenon of using new psychoactive substances (NPS), called designer drugs, has been on rise. Though their production and marketing in Poland is prohibited, reports of the Supreme Audit Office noted...

  • Article
  • Open Access
3 Citations
998 Views
36 Pages

24 October 2024

Interdecadal variations, since the middle of the 20th century, in the seasonal cycle of Southern Hemisphere extratropical synoptic scale weather systems, are studied and related to associated anomalies in Southern Australian rainfall over south-west...