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17 Results Found

  • Article
  • Open Access
36 Citations
5,871 Views
12 Pages

Terretonin N: A New Meroterpenoid from Nocardiopsis sp.

  • Abdelaaty Hamed,
  • Ahmed S. Abdel-Razek,
  • Marcel Frese,
  • Hans Georg Stammler,
  • Atef F. El-Haddad,
  • Tarek M. A. Ibrahim,
  • Norbert Sewald and
  • Mohamed Shaaban

31 January 2018

Terretonin N (1), a new highly oxygenated and unique tetracyclic 6-hydroxymeroterpenoid, was isolated together with seven known compounds from the ethyl acetate extract of a solid-state fermented culture of Nocardiopsis sp. Their structures were eluc...

  • Article
  • Open Access
9 Citations
3,599 Views
16 Pages

15 February 2023

Antarctic krill (Euphausia superba) of the Euphausiidae family comprise one of the largest biomasses in the world and play a key role in the Antarctic marine ecosystem. However, the study of E. superba-derived microbes and their secondary metabolites...

  • Article
  • Open Access
9 Citations
2,585 Views
11 Pages

Identification of Novel Sphydrofuran-Derived Derivatives with Lipid-Lowering Activity from the Active Crude Extracts of Nocardiopsis sp. ZHD001

  • Yuhong Tian,
  • Yongjun Jiang,
  • Zhengshun Wen,
  • Liping Guan,
  • Xiaokun Ouyang,
  • Wanjing Ding and
  • Zhongjun Ma

1 February 2023

Lipid-lowering is one of the most effective methods of prevention and treatment for cardiovascular diseases. However, most clinical lipid-lowering drugs have adverse effects and cannot achieve the desired efficacy in some complex hyperlipidemia patie...

  • Article
  • Open Access
1,036 Views
15 Pages

20 February 2025

Five novel 2-methyl-4-(1-glycerol)furan (MGF) dimers, namely nocardifuran A (1), 13-acetyl-nocardifuran A (2), 15-epi-nocardifuran A (3), nocardifuran B (4), and nocardifuran C (5), were isolated from the Gause liquid fermentation of the marine-deriv...

  • Article
  • Open Access
117 Citations
15,565 Views
14 Pages

22 May 2014

Two sponge-derived actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163, were grown in co-culture and the presence of induced metabolites monitored by 1H NMR. Ten known compounds, including angucycline, diketopiperazine and β-carboline...

  • Article
  • Open Access
31 Citations
7,027 Views
13 Pages

New Cytotoxic Cyclic Peptide from the Marine Sponge-Associated Nocardiopsis sp. UR67

  • Alyaa Hatem Ibrahim,
  • Eman Zekry Attia,
  • Dina Hajjar,
  • Mohamed A. Anany,
  • Samar Yehia Desoukey,
  • Mostafa Ahmed Fouad,
  • Mohamed Salah Kamel,
  • Harald Wajant,
  • Tobias A. M. Gulder and
  • Usama Ramadan Abdelmohsen

21 August 2018

A new cyclic hexapeptide, nocardiotide A (1), together with three known compounds—tryptophan (2), kynurenic acid (3), and 4-amino-3-methoxy benzoic acid (4)—were isolated and identified from the broth culture of Nocardiopsis sp. UR67 stra...

  • Article
  • Open Access
4 Citations
3,518 Views
18 Pages

Bioremediation of Oil-Contaminated Soils Using Biosurfactants Produced by Bacteria of the Genus Nocardiopsis sp.

  • Liliya Biktasheva,
  • Alexander Gordeev,
  • Arina Usova,
  • Anastasia Kirichenko,
  • Polina Kuryntseva and
  • Svetlana Selivanovskaya

9 December 2024

One of the effective and safe methods of soil cleanup from oil pollution is bioremediation by introducing microorganisms or their metabolites. In this study, the effect of biosurfactants produced by Nocardiopsis sp. 3mo on the rate of bioremediation...

  • Article
  • Open Access
50 Citations
8,467 Views
16 Pages

Nocapyrones: α- and γ-Pyrones from a Marine-Derived Nocardiopsis sp.

  • Youngju Kim,
  • Hiromu Ogura,
  • Kazuaki Akasaka,
  • Tsutomu Oikawa,
  • Nobuyasu Matsuura,
  • Chiaki Imada,
  • Hisato Yasuda and
  • Yasuhiro Igarashi

8 July 2014

One new α-pyrone (nocapyrone R (1)), and three known γ-pyrones (nocapyrones B, H and L (2–4)) were isolated from the culture extract of a Nocardiopsis strain collected from marine sediment. Structures of these compounds were determined on the basis...

  • Article
  • Open Access
50 Citations
6,291 Views
11 Pages

Borrelidins C–E: New Antibacterial Macrolides from a Saltern-Derived Halophilic Nocardiopsis sp.

  • Jungwoo Kim,
  • Daniel Shin,
  • Seong-Hwan Kim,
  • Wanki Park,
  • Yoonho Shin,
  • Won Kyung Kim,
  • Sang Kook Lee,
  • Ki-Bong Oh,
  • Jongheon Shin and
  • Dong-Chan Oh

6 June 2017

Chemical investigation of a halophilic actinomycete strain belonging to the genus Nocardiopsis inhabiting a hypersaline saltern led to the discovery of new 18-membered macrolides with nitrile functionality, borrelidins C–E (1–3), along with a previou...

  • Article
  • Open Access
6 Citations
3,003 Views
20 Pages

Evaluation of Antimicrobial Activity by Marine Nocardiopsis dassonvillei against Foodborne Listeria monocytogenes and Shiga Toxin-Producing Escherichia coli

  • Siyanda S. Ngema,
  • Solomuzi H. Khumalo,
  • Michael C. Ojo,
  • Ofentse J. Pooe,
  • Tsolanku S. Malilehe,
  • Albertus K. Basson and
  • Evelyn Madoroba

The emergence of multidrug-resistant pathogens creates public health challenges, prompting a continuous search for effective novel antimicrobials. This study aimed to isolate marine actinomycetes from South Africa, evaluate their in vitro antimicrobi...

  • Review
  • Open Access
27 Citations
6,885 Views
18 Pages

Secondary Metabolites from Marine-Derived Fungi and Actinobacteria as Potential Sources of Novel Colorectal Cancer Drugs

  • Elin Julianti,
  • Ikram Ammar Abrian,
  • Marlia Singgih Wibowo,
  • Muhammad Azhari,
  • Nadya Tsurayya,
  • Fauzia Izzati,
  • Ario Betha Juanssilfero,
  • Asep Bayu,
  • Siti Irma Rahmawati and
  • Masteria Yunovilsa Putra

12 January 2022

Colorectal cancer is one of the most common cancers diagnosed in the world. Chemotheraphy is one of the most common methods used for the pharmacological treatment of this cancer patients. Nevertheless, the adverse effect of chemotherapy is not optimi...

  • Proceeding Paper
  • Open Access
9 Citations
3,166 Views
6 Pages

Plants are affected by various biotic and abiotic stresses due to climate change. Tomato and carrots are important crops that are attacked by various pathogens. Fourteen plant-growth-promoting bacteria (PGPB) belonging to the genera Streptomyces sp....

  • Article
  • Open Access
24 Citations
5,591 Views
16 Pages

Exploration of Chemical Diversity and Antitrypanosomal Activity of Some Red Sea-Derived Actinomycetes Using the OSMAC Approach Supported by LC-MS-Based Metabolomics and Molecular Modelling

  • Noha M. Gamaleldin,
  • Walid Bakeer,
  • Ahmed M. Sayed,
  • Yara I. Shamikh,
  • Ahmed O. El-Gendy,
  • Hossam M. Hassan,
  • Hannes Horn,
  • Usama Ramadan Abdelmohsen and
  • Wael N. Hozzein

22 September 2020

In the present study, we investigated the actinomycetes associated with the Red Sea-derived soft coral Sarcophyton glaucum in terms of biological and chemical diversity. Three strains were cultivated and identified to be members of genera Micromonosp...

  • Article
  • Open Access
25 Citations
136 Views

Detection of Antibiotic-Producing Actinobacteria in the Sediment and Water of Ma'in Thermal Springs (Jordan)

  • Emad I. Hussein,
  • Jacob H. Jacob,
  • Muhamad Ali K. Shakhatreh,
  • Mutaz A. Abd Al-Razaq,
  • Abdul-Salam F. Juhmani and
  • Christopher T. Cornelison

3 December 2018

Introduction: Detection of new Actinobacteria is significant to discover new antibiotics because development of new antibiotics is connected to the characterization of novel bacterial taxa. This study has focused on the identification and isolation o...

  • Article
  • Open Access
38 Citations
4,764 Views
15 Pages

12 October 2021

Biotic stress caused by pathogenic microorganisms leads to damage in crops. Tomato and carrot are among the most important vegetables cultivated worldwide. These plants are attacked by several pathogens, affecting their growth and productivity. Fourt...

  • Article
  • Open Access
30 Citations
6,736 Views
29 Pages

Screening of the High-Rhizosphere Competent Limoniastrum monopetalum’ Culturable Endophyte Microbiota Allows the Recovery of Multifaceted and Versatile Biocontrol Agents

  • Houda Ben Slama,
  • Mohamed Ali Triki,
  • Ali Chenari Bouket,
  • Fedia Ben Mefteh,
  • Faizah N. Alenezi,
  • Lenka Luptakova,
  • Hafsa Cherif-Silini,
  • Armelle Vallat,
  • Tomasz Oszako and
  • Lassaad Belbahri
  • + 1 author

Halophyte Limoniastrum monopetalum, an evergreen shrub inhabiting the Mediterranean region, has well-documented phytoremediation potential for metal removal from polluted sites. It is also considered to be a medicinal halophyte with potent activity a...

  • Article
  • Open Access
18 Citations
5,019 Views
21 Pages

Exploring Core Genes by Comparative Transcriptomics Analysis for Early Diagnosis, Prognosis, and Therapies of Colorectal Cancer

  • Md. Ariful Islam,
  • Md. Bayazid Hossen,
  • Md. Abu Horaira,
  • Md. Alim Hossen,
  • Md. Kaderi Kibria,
  • Md. Selim Reza,
  • Khanis Farhana Tuly,
  • Md. Omar Faruqe,
  • Firoz Kabir and
  • Md. Nurul Haque Mollah
  • + 1 author

21 February 2023

Colorectal cancer (CRC) is one of the most common cancers with a high mortality rate. Early diagnosis and therapies for CRC may reduce the mortality rate. However, so far, no researchers have yet investigated core genes (CGs) rigorously for early dia...