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19 Results Found

  • Article
  • Open Access
2 Citations
2,266 Views
14 Pages

Paleo Distribution and Habitat Risks under Climate Change of Helleborus thibetanus

  • Xiaohua Shi,
  • Lihui Mao,
  • Miao Sun,
  • Guangying Ma and
  • Kaiyuan Zhu

20 March 2023

As an endemic species and the only Helleborus species in China, Helleborus thibetanus is highly valued in medicinal and ornamental applications, and basic research is needed for its further resource conservation and utilization. Considering the inter...

  • Article
  • Open Access
639 Views
25 Pages

Analysis of Phenotypic Diversity and Comprehensive Evaluation of 51 Helleborus L. Hybrid Individuals

  • Liuqing Qu,
  • Bingyu Yuan,
  • Xiaohui Wen,
  • Jia Guo,
  • Jianrang Luo and
  • Xiaohua Shi

20 October 2025

Helleborus orientalis L. is a valuable winter-flowering and understory landscape plant, but its application and breeding are hindered by poor heat tolerance and the lack of a robust germplasm evaluation system. In this study, 51 Helleborus L. hybrid...

  • Article
  • Open Access
462 Views
18 Pages

Substrate composition plays a vital role in the soilless cultivation of Helleborus; high-quality substrates can create optimal growth conditions and enhance plant quality. However, knowledge regarding suitable substrates for Helleborus remains limite...

  • Article
  • Open Access
5 Citations
2,524 Views
12 Pages

31 December 2021

Helleborus niger is an evergreen species, while H. odorus is an herbaceous understorey species. They both develop flowers before the forest canopy layer closes. Their sepals remain after flowering and have multiple biological functions. To further el...

  • Article
  • Open Access
3 Citations
1,960 Views
14 Pages

Deep Simple Epicotyl Morphophysiological Dormancy in Seeds of Endemic Chinese Helleborus thibetanus

  • Xueyan Zhao,
  • Fangyuan Wang,
  • Li Wang,
  • Qing Wang,
  • Ancheng Liu and
  • Yan Li

Helleborus thibetanus is an endemic species in China with important ornamental and medicinal value. However, the seeds have dormancy, and their germination percentage is low under natural conditions. This research was carried out to determine the see...

  • Communication
  • Open Access
1 Citations
852 Views
18 Pages

Preliminary Data on the Antiviral Activity of Helleborus bocconei subsp. intermedius Root Extracts Against Animal Herpesviruses

  • Paola Galluzzo,
  • Santina Di Bella,
  • Sergio Migliore,
  • Maria Valeria Raimondi,
  • Roberta Bivacqua,
  • Gigliola Borgonovo,
  • Salvatore Princiotto,
  • Antonella Girgenti,
  • Laura Palumbo and
  • Vincenza Cannella
  • + 4 authors

Orthoherpesviridae is a large family of enveloped DNA virus. Among the most significant animal-infecting viruses are bovine alphaherpesvirus 1 (BoAHV1), caprine alphaherpesvirus 1 (CpAHV1) and equid alphaherpesvirus 1 (EqAHV1). Research into new meth...

  • Article
  • Open Access
4 Citations
2,409 Views
20 Pages

3 August 2024

Floral nectar is mainly a reward in the form of food for pollinators. In early spring, when snow can still be present, pollinators have trouble finding food. The composition and productivity of nectar in flowers play an important role in a pollinator...

  • Article
  • Open Access
8 Citations
3,274 Views
15 Pages

Comparative Evaluation of the Potential Antitumor of Helleborus purpurascens in Skin and Breast Cancer

  • Ciprian Nicolae Pilut,
  • Aniko Manea,
  • Ioana Macasoi,
  • Amadeus Dobrescu,
  • Doina Georgescu,
  • Roxana Buzatu,
  • Alin Faur,
  • Stefania Dinu,
  • Doina Chioran and
  • Daniel Malița
  • + 3 authors

12 January 2022

In the field of oncology, the plant kingdom has an inexhaustible supply of bioactive compounds. Phytochemical compounds isolated from Helleborus species have been found to be useful in various chronic diseases. This has brought Helleborus to the atte...

  • Article
  • Open Access
5 Citations
2,637 Views
10 Pages

Immunomodulatory Effect of Helleborus purpurascens Waldst. & Kit.

  • Alice Grigore,
  • Corina Bubueanu,
  • Lucia Pirvu,
  • Georgeta Neagu,
  • Ionica Bejanaru,
  • Virginia Vulturescu,
  • Minerva Panteli and
  • Iuksel Rasit

23 September 2021

(1) Background: Helleborus purpurascens Waldst. & Kit. (hellebore) is a plant species found mainly in Balkans and the Carpathians, and it is traditionally used for a variety of ailments since the time of Hippocrates. The aim of this study was to...

  • Article
  • Open Access
21 Citations
4,329 Views
18 Pages

Genetic Diversity and Range Dynamics of Helleborus odorus subsp. cyclophyllus under Different Climate Change Scenarios

  • Georgia Fassou,
  • Konstantinos Kougioumoutzis,
  • Gregoris Iatrou,
  • Panayiotis Trigas and
  • Vasileios Papasotiropoulos

1 June 2020

Research Highlights: The effects of climate change on habitat loss, range shift and/or genetic impoverishment of mid-elevation plants has received less attention compared to alpine species. Moreover, genetic diversity patterns of mountain forest herb...

  • Article
  • Open Access
11 Citations
3,195 Views
31 Pages

Wild-Grown Romanian Helleborus purpurascens Approach to Novel Chitosan Phyto-Nanocarriers—Metabolite Profile and Antioxidant Properties

  • Adina-Elena Segneanu,
  • Gabriela Vlase,
  • Titus Vlase,
  • Crina Andreea Sicoe,
  • Maria Viorica Ciocalteu,
  • Dumitru Daniel Herea,
  • Ovidiu-Florin Ghirlea,
  • Ioan Grozescu and
  • Valentin Nanescu

4 October 2023

The current nanomedicinal approach combines medicinal plants and nanotechnology to create new scaffolds with enhanced bioavailability, biodistribution and controlled release. In an innovative approach to herb encapsulation in nanosized chitosan matri...

  • Article
  • Open Access
20 Citations
7,825 Views
18 Pages

Helleborus purpurascens—Amino Acid and Peptide Analysis Linked to the Chemical and Antiproliferative Properties of the Extracted Compounds

  • Adina-Elena Segneanu,
  • Ioan Grozescu,
  • Florentina Cziple,
  • Daniel Berki,
  • Daniel Damian,
  • Cristina Mariana Niculite,
  • Alexandru Florea and
  • Mircea Leabu

11 December 2015

There is a strong drive worldwide to discover and exploit the therapeutic potential of a large variety of plants. In this work, an alcoholic extract of Helleborus purpurascens (family Ranunculaceae) was investigated for the identification of amino ac...

  • Article
  • Open Access
1 Citations
1,090 Views
18 Pages

Divergent Photosynthetic Strategies of Lupinus polyphyllus and Helleborus viridis During Cold Acclimation and Freezing–Thaw Recovery

  • Pengyuan Xie,
  • Yining Zhao,
  • Xin Zhao,
  • Linbo Xu,
  • Kai Wang,
  • Ruidong Jia,
  • Yaping Kou,
  • Hong Ge,
  • Wenjun Wang and
  • Shuhua Yang

17 February 2025

Low temperatures can significantly affect the growth of ornamental plants, emphasizing the importance of improving their cold tolerance. However, comparative studies on the photosynthetic responses of sun and shade plants to low temperatures remain l...

  • Article
  • Open Access
11 Citations
2,698 Views
13 Pages

Energy Efficiency of LEDs during Micropropagation of Helleborus ‘Molly’s White’

  • Karolina Nowakowska,
  • Katarzyna Kowalczyk,
  • Anna Pawełczak and
  • Janina Gajc-Wolska

For many years, there has been a growing trend toward producing plants using tissue culture, the most efficient method at present. Every year, more and more protocols for micropropagation of economically valuable species are appearing. Many factors i...

  • Article
  • Open Access
1 Citations
1,836 Views
19 Pages

Furostanol Saponins and Ecdysteroids from Plants of the Genus Helleborus as Phagostimulants and Predator Deterrents for Larvae of Two Monophadnus Sawfly Species

  • Jose M. Prieto,
  • Alison M. Barker,
  • Urs Schaffner,
  • Joëlle Quetin-Leclercq,
  • Alessandra Braca and
  • Jean-Luc Boevé

12 August 2024

Sawfly species of the genus Monophadnus are specialised on Ranunculaceae plants from which the larvae can sequester furostanol saponins into the haemolymph, mainly (25R)-26-[(α-L-rhamnopyranosyl)oxy]-22α-methoxyfurost-5-en-3β-yl-O-&b...

  • Expression of Concern
  • Open Access
1 Citations
4,257 Views
1 Page

As Editor in Chief of Molecules and Academic Editor of the article [1], respectively, we wish to advise readers that Molecules has been informed that its authorship is currently in dispute and the subject of a formal lawsuit.[...]

  • Editorial
  • Open Access
3,688 Views
1 Page

10 January 2018

The article [1] published in Molecules was the subject of a law suit related to authorship. We previously published an Expression of Concern to highlight this fact to readers[...]

  • Article
  • Open Access
11 Citations
3,418 Views
22 Pages

Bioinformatics Tools for the Analysis of Active Compounds Identified in Ranunculaceae Species

  • Cătălina Mareş,
  • Ana-Maria Udrea,
  • Nicoleta Anca Şuţan and
  • Speranţa Avram

The chemical compounds from extracts of three Ranunculaceae species, Aconitum toxicum Rchb., Anemone nemorosa L. and Helleborus odorus Waldst. & Kit. ex Willd., respectively, were isolated using the HPLC purification technique and analyzed from a...

  • Article
  • Open Access
13 Citations
4,048 Views
24 Pages

16 November 2022

This study analyzed the use of plants and fungi, some wild and some cultivated, in three municipalities of Lika-Senj County (Perušić, Gospić and Lovinac). The range of the study area was about 60 km. Forty in-depth semi-structured in...