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4 Results Found

  • Article
  • Open Access
5 Citations
2,415 Views
14 Pages

Coleon U, Isolated from Plectranthus mutabilis Codd., Decreases P-Glycoprotein Activity Due to Mitochondrial Inhibition

  • Sofija Jovanović Stojanov,
  • Epole N. Ntungwe,
  • Jelena Dinić,
  • Ana Podolski-Renić and ,
  • Milica Pajović,
  • Patrícia Rijo and
  • Milica Pešić
  • + 2 authors+ 0 author

Multidrug resistance in cancer is often mediated by P-glycoprotein. Natural compounds have been suggested as a fourth generation of P-glycoprotein inhibitors. Coleon U, isolated from Plectranthus mutabilis Codd., was reported to modulate P-glycoprote...

(This article belongs to the Special Issue Bioactive Molecules from Plants: Discovery and Pharmaceutical Applications, 3rd Edition)
  • Article
  • Open Access
1 Citations
1,065 Views
9 Pages

Chemical Constituents from Coleus strobilifer and Their Xanthine Oxidase Inhibitory Activity

  • Jia-Xu Qin,
  • Yang Hong,
  • Xiao-Na Gan,
  • Ting-Zhao Li and ,
  • Meng-Qi Wang,
  • Xiang-Wei Zheng,
  • Bo Li,
  • Xin Fang and
  • Shuang Liang
  • + 4 authors+ 0 author

22 December 2025

Coleus strobilifer, the dried rhizome and root of Coleus strobilifer (Roxb.) A.J. Paton, is widely used for dampness-detoxification and detumescence in Chinese folklore. This study marks the first comprehensive investigation into the chemical composi...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
17 Citations
4,679 Views
12 Pages

Antimycobacterial, Cytotoxic, and Antioxidant Activities of Abietane Diterpenoids Isolated from Plectranthus madagascariensis

  • Kadidiatou O. Ndjoubi,
  • Rajan Sharma,
  • Jelili A. Badmus,
  • Ayesha Jacobs and ,
  • Audrey Jordaan,
  • Jeanine Marnewick,
  • Digby F. Warner and
  • Ahmed A. Hussein
  • + 3 authors+ 0 author

19 January 2021

Medicinal plants of the Plectranthus genus (Lamiaceae) are well known for their ethnomedicinal applications. Plectranthus madagascariensis, which is native to South Africa, is traditionally used in the treatment of respiratory conditions, scabies, an...

  • Communication
  • Open Access
23 Citations
7,247 Views
13 Pages

Comparison Study of Different Extracts of Plectranthus madagascariensis, P. neochilus and the Rare P. porcatus (Lamiaceae): Chemical Characterization, Antioxidant, Antimicrobial and Cytotoxic Activities

  • Diogo Matias,
  • Marisa Nicolai,
  • Ana Sofia Fernandes,
  • Nuno Saraiva and ,
  • Joana Almeida,
  • Lucília Saraiva,
  • Célia Faustino,
  • Ana María Díaz-Lanza,
  • Catarina P. Reis and
  • Patrícia Rijo
  • + 5 authors+ 0 author

Medicinal plants of the Plectranthus genus (Lamiaceae) are known for their ethnopharmacological relevance, mainly against infectious, dermatologic and gastrointestinal pathologies. Three Plectranthus species originated from South Africa, namely P. ma...

(This article belongs to the Section Natural and Bio-derived Molecules)