As Molecules (ISSN 1420-3049) is an open access journal, you have free and unlimited access to the full text of all articles. We invite you to read the following highly cited papers published in 2024–2025 in the “Organic Chemistry” Section:

1. “Research Progress on Benzimidazole Fungicides: A Review”
by Song Bai, Miaohe Zhang, Shouying Tang, Miao Li, Rong Wu, Suran Wan, Lijun Chen, Xian Wei and Feifei Li
Molecules 2024, 29(6), 1218; https://doi.org/10.3390/molecules29061218
Available online: https://www.mdpi.com/1420-3049/29/6/1218

2. “Imidazopyridine Family: Versatile and Promising Heterocyclic Skeletons for Different Applications”
by Giorgio Volpi, Enzo Laurenti and Roberto Rabezzana
Molecules 2024, 29(11), 2668; https://doi.org/10.3390/molecules29112668
Available online: https://www.mdpi.com/1420-3049/29/11/2668

3. “Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021–Present)”
by Heba T. Abdel-Mohsen, Manal M. Anwar, Nesreen S. Ahmed, Somaia S. Abd El-Karim and Sameh H. Abdelwahed
Molecules 2024, 29(4), 875; https://doi.org/10.3390/molecules29040875
Available online: https://www.mdpi.com/1420-3049/29/4/875

4. “Syn-Propanethial S-Oxide as an Available Natural Building Block for the Preparation of Nitro-Functionalized, Sulfur-Containing Five-Membered Heterocycles: An MEDT Study”
by Mikołaj Sadowski, Ewa Dresler, Karolina Zawadzińska, Aneta Wróblewska and Radomir Jasiński
Molecules 2024, 29(20), 4892; https://doi.org/10.3390/molecules29204892
Available online: https://www.mdpi.com/1420-3049/29/20/4892

5. “Hydrazides as Powerful Tools in Medicinal Chemistry: Synthesis, Reactivity, and Biological Applications”
by Sofia Teixeira, Elisabete M. S. Castanheira and M. Alice Carvalho
Molecules 2025, 30(13), 2852; https://doi.org/10.3390/molecules30132852
Available online: https://www.mdpi.com/1420-3049/30/13/2852

6. “Recent Advances in the Synthesis of Organic Thiocyano (SCN) and Selenocyano (SeCN) Compounds, Their Chemical Transformations and Bioactivity”
by Rodrigo Abonia, Daniel Insuasty, Juan-Carlos Castillo and Kenneth K. Laali
Molecules 2024, 29(22), 5365; https://doi.org/10.3390/molecules29225365
Available online: https://www.mdpi.com/1420-3049/29/22/5365

7. “Recent Progress on the Synthesis of Bipyridine Derivatives”
by Yoshinori Yamanoi
Molecules 2024, 29(3), 576; https://doi.org/10.3390/molecules29030576
Available online: https://www.mdpi.com/1420-3049/29/3/576

8. “Phthalocyanines Conjugated with Small Biologically Active Compounds for the Advanced Photodynamic Therapy: A Review”
by Kyrylo Chornovolenko and Tomasz Koczorowski
Molecules 2025, 30(15), 3297; https://doi.org/10.3390/molecules30153297
Available online: https://www.mdpi.com/1420-3049/30/15/3297

9. “Quinolin-4-ones: Methods of Synthesis and Application in Medicine”
by Katarzyna Gach-Janczak, Justyna Piekielna-Ciesielska, Jakub Waśkiewicz, Kamil Krakowiak, Karol Wtorek and Anna Janecka
Molecules 2025, 30(1), 163; https://doi.org/10.3390/molecules30010163
Available online: https://www.mdpi.com/1420-3049/30/1/163

10. “Recent Advancements in Photocatalytic Synthesis of Five Membered Nitrogen Heterocycles and Their Derivatives”
by Zeeshan Haider, Ravi Archana and Heongkyu Ju
Molecules 2025, 30(17), 3490; https://doi.org/10.3390/molecules30173490
Available online: https://www.mdpi.com/1420-3049/30/17/3490

11. “Medium-Sized Ring Expansion Strategies: Enhancing Small-Molecule Library Development”
by Hwiyeong Lee, Jonghoon Kim and Minseob Koh
Molecules 2024, 29(7), 1562; https://doi.org/10.3390/molecules29071562
Available online: https://www.mdpi.com/1420-3049/29/7/1562

12. “Synthesis, In Vivo Anticonvulsant Activity Evaluation and In Silico Studies of Some Quinazolin-4(3H)-One Derivatives”
by Raluca Pele, Gabriel Marc, Cristina Mogoșan, Anamaria Apan, Ioana Ionuț, Brîndușa Tiperciuc, Cristina Moldovan, Cătălin Araniciu, Ilioara Oniga, Adrian Pîrnău et al.
Molecules 2024, 29(9), 1951; https://doi.org/10.3390/molecules29091951
Available online: https://www.mdpi.com/1420-3049/29/9/1951

13. “Water-Soluble Trityl Radicals for Fluorescence Imaging”
by Mona E. Arnold, Larissa Schoeneburg, Markus Lamla and Alexander J. C. Kuehne
Molecules 2024, 29(5), 995; https://doi.org/10.3390/molecules29050995
Available online: https://www.mdpi.com/1420-3049/29/5/995

14. “New Library of Iodo-Quinoline Derivatives Obtained by an Alternative Synthetic Pathway and Their Antimicrobial Activity”
by Cristina Maria Al-Matarneh, Alina Nicolescu, Ioana Cristina Marinaş, Mădalina Diana Găboreanu, Sergiu Shova, Andrei Dascălu, Mihaela Silion and Mariana Pinteală
Molecules 2024, 29(4), 772; https://doi.org/10.3390/molecules29040772  
Available online: https://www.mdpi.com/1420-3049/29/4/772  

15. “BODIPY Compounds Substituted on Boron”
by Marko Bogomolec, Mladena Glavaš and Irena Škorić
Molecules 2024, 29(21), 5157; https://doi.org/10.3390/molecules29215157  
Available online: https://www.mdpi.com/1420-3049/29/21/5157