Pediatric Viral Gastroenteritis

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Human Virology and Viral Diseases".

Deadline for manuscript submissions: 31 January 2027 | Viewed by 8

Special Issue Editors


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Guest Editor
1. Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
2. Department of Family Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Interests: norovirus; rotavirus; gastroenteritis

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Guest Editor
UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Interests: childhood diarrhea; vaccines; nutrition

Special Issue Information

Dear Colleagues,

Children’s gastrointestinal tract is commonly infected with a wide range of viruses as demonstrated by deep sequencing studies of children’s stools. Fortunately, only a handful of these viruses have been associated with gastrointestinal symptoms in children. The most notorious is rotavirus, which infects nearly all children in the first 2 years of age causing vomiting and/or diarrhea that might lead to severe dehydration. Despite the availability of vaccines, it is estimated that rotavirus causes thousands of deaths in children younger than 5 years of age. The second most notorious is norovirus, which is another leading cause of pediatric acute gastroenteritis and the major cause of foodborne associated viral gastroenteritis worldwide. Efforts to develop a pediatric norovirus vaccine has been hampered by the rapid evolution of these viruses and the lack of cell culture systems that support vaccine production. Sapovirus is emerging as the second most common cause of pediatric acute gastroenteritis in the US, and Astrovirus and Adenovirus remain other important causes. Studies focused on pediatric acute gastroenteritis may increase our understanding of the molecular epidemiology of these viruses in early life, immune responses following natural infections, and the role of children’s environment in facilitating infections and disease.

This Special Issue aims to bring together cutting-edge research and comprehensive reviews on the epidemiology, pathogenesis, diagnostics, management, and prevention of viral gastroenteritis in children. We invite original research articles, reviews, and communications that address current challenges and future directions in the field.

Dr. Filemon Bucardo
Dr. Sylvia Becker-Dreps
Guest Editors

Manuscript Submission Information

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Keywords

  • gastrointestinal track
  • rotavirus
  • norovirus
  • sapovirus
  • astrovirus

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Published Papers

This special issue is now open for submission.
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