Hepatitis Virus Genetic Heterogeneity: Impact in Epidemiology and Clinical Pathology
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Human Virology and Viral Diseases".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 7
Special Issue Editors
Interests: viral hepatitis; innovation in the diagnosis of hepatitis; molecular epidemiology; epidemiology; the biology of viral hepatitis; vulnerable high-risk populations; indigenous populations
Special Issues, Collections and Topics in MDPI journals
Interests: viral hepatitis; COVID-19
Interests: PCR; molecular virology; nucleic acid extraction; virus replication; molecular epidemiology; virus diseases; viral infection; molecular cloning; virus cultivation; hepatitis viruses
Special Issue Information
Dear Colleagues,
Viral hepatitis (A-D) remains a global health concern, especially due to the clinical impact caused by chronic infections (B\D and C). In addition to clinical manifestations, molecular and epidemiological investigations have become essential tools for understanding viral diversity, transmission dynamics, geographical distribution and mutations associated with resistance. This Special Issue highlights advances in the genetic and epidemiological characterization of hepatitis viruses, with an emphasis on molecular surveillance, the distribution of genotypes and the impact of viral variants on diagnosis, treatment and public health strategies.
Despite the robust literature on viral hepatitis, there are still gaps in the distribution of these viruses in specific population groups; alternative diagnostic tests with high sensitivity, specificity and multiplex detection, that can help to identify active cases particularly in vulnerable populations; and genomic surveillance studies with epidemiological mapping of circulating genotypes, mutations associated with drug resistance and immune escape that can select specific viral populations, correlate with disease progression and risk of complications.
This Special Issue of Viruses invites original and review articles on viral hepatitis that contribute to the understanding of virus detection and genotypes. We are seeking studies that investigate the detection and characterization of hepatitis viruses using molecular tools, including innovative approaches. Emphasis will be placed on the application of sequencing technologies for viral genotyping and genomic surveillance. We also encourage submissions that address the identification of resistance-associated and immune escape mutations, as well as bioinformatics strategies to analyze viral diversity and transmission dynamics. The development and validation of diagnostic tools, especially those applicable in co-infection or resource-limited scenarios, are also of interest.
Dr. Livia Melo Villar
Dr. Lucas Lima da Silva
Dr. Diego Flichman
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- viral hepatitis
- molecular diagnostics
- genotyping
- molecular epidemiology
- antiviral therapy
- drug resistance
- genomic surveillance
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